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Biology and Biochemistry

D-Index
65
Citations
15709
World Ranking
9124
National Ranking
4050

Overview

Dan Mercola is affiliated with the University of California, Irvine in the United States. Their research spans multiple fields within medical and biological sciences, with a particular emphasis on cancer.

The main fields of study for Dan Mercola include Medicine and Biochemistry, Genetics and Molecular Biology. Within these areas, they have focused on several subfields, such as Cancer Research, Pulmonary and Respiratory Medicine, Molecular Biology, Oncology, and Reproductive Medicine.

The scientist's work concentrates on multiple key topics. These include Cancer-related molecular mechanisms research, Prostate Cancer Treatment and Research, Molecular Biology Techniques and Applications, Ovarian cancer diagnosis and treatment, Cancer Immunotherapy and Biomarkers, Renal cell carcinoma treatment, and Reproductive System and Pregnancy.

Dan Mercola has contributed to a range of recent papers, notable for their focus on cancer and molecular biology. These papers include:

  • Transcriptome Analysis of Ovarian and Uterine Clear Cell Malignancies, 2020, Frontiers in Oncology
  • RNA expression differences in prostate tumors and tumor-adjacent stroma between Black and White Americans, 2021, Oncotarget
  • Expression of Endogenous Retroviral RNA in Prostate Tumors has Prognostic Value and Shows Differences among Americans of African Versus European/Middle Eastern Ancestry, 2021, Cancers
  • Spatial Profiling of the Prostate Cancer Tumor Microenvironment Reveals Multiple Differences in Gene Expression and Correlation with Recurrence Risk, 2022, Cancers
  • Patterns in whole genome RNA sequencing of clear cell ovarian and uterine malignancies and correlations with PD-L1 expression and immunologic microenvironment, 2020, Gynecologic Oncology

The frequent co-authors collaborating with Dan Mercola include Farah Rahmatpanah, Michael McClelland, Gabriela De Robles, Michael B. Lilly, and Vinay Kumar.

Dan Mercola's publications have appeared repeatedly in several venues, with most frequent appearances in Cancers and Cancer Research. Additional publication venues include Frontiers in Oncology, Oncotarget, and Gynecologic Oncology.

Best Publications

  • Insulin: The Structure in the Crystal and its Reflection in Chemistry and Biology by

    Tom Blundell;Guy Dodson;Dorothy Hodgkin;Dan Mercola

  • Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

    Tod Smeal;Bernard Binetruy;Bernard Binetruy;Daniel A. Mercola;Michael Birrer

  • The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling

    Virolle T;Adamson Ed;Baron;Birle D

  • Eradication of established intracranial rat gliomas by transforming growth factor beta antisense gene therapy

    Habib Fakhrai;Oliver Dorigo;Daniel L. Shawler;Hong Lin

  • Oncoprotein-mediated signalling cascade stimulates c-Jun activity by phosphorylation of serines 63 and 73.

    T Smeal;B Binetruy;D Mercola;A Grover-Bardwick

  • The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGFbeta1, PTEN, p53, and fibronectin.

    Baron;E D Adamson;A Calogero;G Ragona

  • Atomic Positions in Rhombohedral 2-Zinc Insulin Crystals

    Blundell Tl;Cutfield Jf;Cutfield Sm;Dodson Ej

  • Plasma-derived exosomal survivin, a plausible biomarker for early detection of prostate cancer.

    Salma Khan;Jessica M. S. Jutzy;Malyn May A. Valenzuela;David Turay

  • Structure of insulin in 4-zinc insulin

    Graham Bentley;Eleanor Dodson;Guy Dodson;Dorothy Hodgkin

  • Decreased Egr‐1 expression in human, mouse and rat mammary cells and tissues correlates with tumor formation

    Ruo-Pan Huang;Yan Fan;Ian De Belle;Christina Niemeyer

  • Suppression of growth and transformation and induction of apoptosis by EGR-1.

    C Liu;V M Rangnekar;E Adamson;D Mercola

  • The Jun kinase/stress-activated protein kinase pathway functions to regulate DNA repair and inhibition of the pathway sensitizes tumor cells to cisplatin.

    Olga Potapova;Ali Haghighi;Frédéric Bost;Chaoting Liu

  • Siah2-dependent concerted activity of HIF and FoxA2 regulates formation of neuroendocrine phenotype and neuroendocrine prostate tumors.

    Jianfei Qi;Koh Nakayama;Robert D. Cardiff;Alexander D. Borowsky

  • In silico dissection of cell-type-associated patterns of gene expression in prostate cancer

    Robert O. Stuart;William Wachsman;William Wachsman;Charles C. Berry;Jessica Wang-Rodriguez;Jessica Wang-Rodriguez

  • Identification of promoters bound by c-Jun/ATF2 during rapid large-scale gene activation following genotoxic stress.

    Jun Hayakawa;Shalu Mittal;Yipeng Wang;Kemal S. Korkmaz

  • Inhibition of extracellular signal-regulated protein kinase or c-Jun N-terminal protein kinase cascade, differentially activated by cisplatin, sensitizes human ovarian cancer cell line.

    Jun Hayakawa;Masahide Ohmichi;Hirohisa Kurachi;Hiromasa Ikegami

  • Transcription factor EGR-1 suppresses the growth and transformation of human HT-1080 fibrosarcoma cells by induction of transforming growth factor beta 1.

    Chaoting Liu;Eileen Adamson;Dan Mercola

  • The activation of c-Jun NH2-terminal kinase (JNK) by DNA-damaging agents serves to promote drug resistance via activating transcription factor 2 (ATF2)-dependent enhanced DNA repair.

    Jun Hayakawa;Chantal Depatie;Masahide Ohmichi;Dan Mercola

  • Molecular determinants of AHPN (CD437)-induced growth arrest and apoptosis in human lung cancer cell lines.

    Yin Li;Bingzhen Lin;Anissa Agadir;Ru Liu

  • The JUN Kinase/Stress-activated Protein Kinase Pathway Is Required for Epidermal Growth Factor Stimulation of Growth of Human A549 Lung Carcinoma Cells

    Frédéric Bost;Robert McKay;Nicholas Dean;Dan Mercola

Frequent Co-Authors

Michael McClelland
Michael McClelland University of California, Irvine
Eileen D. Adamson
Eileen D. Adamson Sanford Burnham Prebys Medical Discovery Institute
James A. Koziol
James A. Koziol Scripps Research Institute
Guy Dodson
Guy Dodson University of York
Tom L. Blundell
Tom L. Blundell University of Cambridge
Olga Potapova
Olga Potapova National Institutes of Health
Shizhong Xu
Shizhong Xu University of California, Riverside
Eleanor J. Dodson
Eleanor J. Dodson University of York
John C. Reed
John C. Reed Johnson & Johnson (United States)
Nicholas M. Dean
Nicholas M. Dean Ionis Pharmaceuticals (United States)

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