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Chemistry

D-Index
48
Citations
6794
World Ranking
15404
National Ranking
293

Overview

Nagula Shankaraiah is affiliated with the Indian Institute of Chemical Technology in India. Their research primarily spans the fields of Chemistry and Biochemistry, Genetics, and Molecular Biology, with a strong emphasis on Organic Chemistry and Molecular Biology as subfields. Their scientific contributions also extend into Materials Chemistry, Oncology, and Pharmacology.

Their work covers various key topics including:

  • Synthesis and biological activity
  • Catalytic C-H Functionalization Methods
  • Click Chemistry and Applications
  • Cancer therapeutics and mechanisms
  • Synthesis and bioactivity of alkaloids
  • Synthesis and Biological Evaluation
  • Synthesis and Characterization of Heterocyclic Compounds

Shankaraiah has published extensively, with notable recent papers including:

  • Recent advances in multi-component reactions and their mechanistic insights: a triennium review, 2021, Organic Chemistry Frontiers
  • Expedition of sulfur-containing heterocyclic derivatives as cytotoxic agents in medicinal chemistry: A decade update, 2021, Medicinal Research Reviews
  • Structural insights of oxindole based kinase inhibitors as anticancer agents: Recent advances, 2021, European Journal of Medicinal Chemistry
  • Anticancer potential of spirocompounds in medicinal chemistry: A pentennial expedition, 2021, European Journal of Medicinal Chemistry
  • An insight into medicinal attributes of dithiocarbamates: Bird's eye view, 2020, Bioorganic Chemistry

The venues where Shankaraiah's research is frequently published include:

  • Bioorganic Chemistry
  • Organic & Biomolecular Chemistry
  • ChemistrySelect
  • Asian Journal of Organic Chemistry
  • Bioorganic & Medicinal Chemistry Letters

Collaborations are a significant aspect of their work, with frequent co-authors being:

  • Akash P. Sakla
  • Ramya Tokala
  • Stephy Elza John
  • Darshana Bora
  • Jay Prakash Soni

Best Publications

  • Recent advances in multi-component reactions and their mechanistic insights: a triennium review

    Stephy Elza John;Shivani Gulati;Nagula Shankaraiah

  • Synthesis of 1,2,3-triazole-linked pyrrolobenzodiazepine conjugates employing 'click' chemistry : DNA-binding affinity and anticancer activity

    Ahmed Kamal;N. Shankaraiah;V. Devaiah;K. Laxma Reddy

  • Synthesis and anticancer activity of chalcone-pyrrolobenzodiazepine conjugates linked via 1,2,3-triazole ring side-armed with alkane spacers.

    Ahmed Kamal;S. Prabhakar;M. Janaki Ramaiah;P. Venkat Reddy

  • Spirooxindole-derived morpholine-fused-1,2,3-triazoles: Design, synthesis, cytotoxicity and apoptosis inducing studies.

    Kishna Ram Senwar;Pankaj Sharma;T. Srinivasa Reddy;Manish Kumar Jeengar

  • Solid-phase synthesis of new pyrrolobenzodiazepine-chalcone conjugates: DNA-binding affinity and anticancer activity.

    Ahmed Kamal;N. Shankaraiah;S. Prabhakar;Ch. Ratna Reddy

  • DNA-binding affinity and anticancer activity of β-carboline-chalcone conjugates as potential DNA intercalators: Molecular modelling and synthesis.

    Nagula Shankaraiah;K.P. Siraj;Shalini Nekkanti;Vunnam Srinivasulu

  • Expedition of sulfur-containing heterocyclic derivatives as cytotoxic agents in medicinal chemistry: A decade update.

    Kritika Laxmikeshav;Pooja Kumari;Nagula Shankaraiah

  • Water mediated Heck and Ullmann couplings by supported palladium nanoparticles: importance of surface polarity of the carbon spheres

    Ahmed Kamal;Vunnam Srinivasulu;B. N. Seshadri;Nagula Markandeya

  • Design and synthesis of dithiocarbamate linked β-carboline derivatives: DNA topoisomerase II inhibition with DNA binding and apoptosis inducing ability

    Ahmed Kamal;Manda Sathish;V. Lakshma Nayak;Vunnam Srinivasulu

  • Synthesis and biological evaluation of new benzimidazole-thiazolidinedione hybrids as potential cytotoxic and apoptosis inducing agents.

    Pankaj Sharma;T. Srinivasa Reddy;Dinesh Thummuri;Kishna Ram Senwar

  • Design and synthesis of C3-tethered 1,2,3-triazolo-β-carboline derivatives: Anticancer activity, DNA-binding ability, viscosity and molecular modeling studies.

    Nagula Shankaraiah;Chetna Jadala;Shalini Nekkanti;Kishna Ram Senwar

  • Structural insights of oxindole based kinase inhibitors as anticancer agents: Recent advances.

    Prajwal Dhokne;Akash P. Sakla;Nagula Shankaraiah

  • Anticancer potential of spirocompounds in medicinal chemistry: A pentennial expedition.

    Darshana Bora;Anjali Kaushal;Nagula Shankaraiah

  • Conventional and microwave-assisted synthesis of new 1H-benzimidazole-thiazolidinedione derivatives: A potential anticancer scaffold

    Pankaj Sharma;T. Srinivasa Reddy;Niggula Praveen Kumar;Kishna Ram Senwar

  • Design and synthesis of C3-pyrazole/chalcone-linked beta-carboline hybrids: antitopoisomerase I, DNA-interactive, and apoptosis-inducing anticancer agents.

    Ahmed Kamal;Vunnam Srinivasulu;V. Lakshma Nayak;Manda Sathish

  • An insight into medicinal attributes of dithiocarbamates: Bird's eye view.

    Sangita Dattatray Shinde;Akash P. Sakla;Nagula Shankaraiah

  • Novel Supramolecular Palladium Catalyst for the Asymmetric Reduction of Imines in Aqueous Media

    Wender A. da Silva;Manoel T. Rodrigues;N. Shankaraiah;Renan B. Ferreira

  • Copper Oxide Nanoparticles Supported on Graphene Oxide‐ Catalyzed S‐Arylation: An Efficient and Ligand‐Free Synthesis of Aryl Sulfides

    Ahmed Kamal;Vunnam Srinivasulu;J. N. S. R. C Murty;Nagula Shankaraiah

  • Exploration of carbamide derived pyrimidine-thioindole conjugates as potential VEGFR-2 inhibitors with anti-angiogenesis effect

    Sravani Sana;Velma Ganga Reddy;Sonal Bhandari;T. Srinivasa Reddy

  • Synthesis of podophyllotoxin linked β-carboline congeners as potential anticancer agents and DNA topoisomerase II inhibitors

    Manda Sathish;Botla Kavitha;V. Lakshma Nayak;Yellaiah Tangella

  • Recent Advances in the Solid-Phase Combinatorial Synthetic Strategies for the Quinoxaline, Quinazoline and Benzimidazole Based Privileged Structures

    A Kamal;K.L Reddy;Devaiah;N Shankaraiah

  • Design, synthesis and apoptosis inducing effect of novel (Z)-3-(3′-methoxy-4′-(2-amino-2-oxoethoxy)-benzylidene)indolin-2-ones as potential antitumour agents

    Kishna Ram Senwar;T. Srinivasa Reddy;Dinesh Thummuri;Pankaj Sharma

  • H2O-mediated isatin spiro-epoxide ring opening with NaCN: Synthesis of novel 3-tetrazolylmethyl-3-hydroxy-oxindole hybrids and their anticancer evaluation.

    Pankaj Sharma;Kishna Ram Senwar;Manish Kumar Jeengar;T. Srinivasa Reddy

  • Recent advances in the solid-phase combinatorial synthetic strategies for the benzodiazepine based privileged structures.

    Ahmed Kamal;K. L. Reddy;V. Devaiah;N. Shankaraiah

Frequent Co-Authors

Ahmed Kamal
Ahmed Kamal Jamia Hamdard
Suresh K. Bhargava
Suresh K. Bhargava RMIT University
Marcos N. Eberlin
Marcos N. Eberlin Universidade Presbiteriana Mackenzie
Balasubramanian Sridhar
Balasubramanian Sridhar Indian Institute of Chemical Technology
Paul Knochel
Paul Knochel Ludwig-Maximilians-Universität München
G. Narahari Sastry
G. Narahari Sastry North East Institute of Science and Technology

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