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David E. Thurston

D-Index & Metrics

Chemistry

D-Index
59
Citations
9742
World Ranking
10385
National Ranking
590

David E. Thurston publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where David E. Thurston sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 255 publications — 51st percentile

51% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

David E. Thurston D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where David E. Thurston sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 59 D-Index — 44th percentile

44% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

David E. Thurston is affiliated with King's College London in the United Kingdom. Their research primarily focuses on Medicine, with a notable emphasis on Oncology, Radiology, Nuclear Medicine and Imaging, Molecular Biology, Organic Chemistry, and Genetics as subfields.

The scientist's main research topics include the exploration of HER2/EGFR in Cancer Research, Monoclonal and Polyclonal Antibodies Research, Cancer therapeutics and mechanisms, CAR-T cell therapy research, Synthesis and pharmacology of benzodiazepine derivatives, Chronic Lymphocytic Leukemia Research, and Multiple Myeloma Research and Treatments.

David E. Thurston's recent publications include:

  • Target Antigen Attributes and Their Contributions to Clinically Approved Antibody-Drug Conjugates (ADCs) in Haematopoietic and Solid Cancers, 2023, Cancers
  • A Novel Antibody-Drug Conjugate (ADC) Delivering a DNA Mono-Alkylating Payload to Chondroitin Sulfate Proteoglycan (CSPG4)-Expressing Melanoma, 2020, Cancers
  • Rapid conjugation of antibodies to toxins to select candidates for the development of anticancer Antibody-Drug Conjugates (ADCs), 2020, Scientific Reports
  • Anti-EGFR Antibody-Drug Conjugate Carrying an Inhibitor Targeting CDK Restricts Triple-Negative Breast Cancer Growth, 2024, Clinical Cancer Research
  • UPLC-based assay to assess the hydrophobicity of Antibody-Drug Conjugate (ADC) payloads, 2020, Journal of Chromatography B

Their frequent co-authors include Khondaker Miraz Rahman, Paul J. Jackson, Paolo Andriollo, George Procopiou, and Sophia N. Karagiannis. These collaborations have been sustained across multiple publications.

David E. Thurston has published in several venues with some frequency, primarily in Cancer Research, followed by Cancers, Scientific Reports, Clinical Cancer Research, and Haematologica.

Best Publications

  • A Potent Anti-CD70 Antibody–Drug Conjugate Combining a Dimeric Pyrrolobenzodiazepine Drug with Site-Specific Conjugation Technology

    Scott C. Jeffrey;Patrick J. Burke;Robert P. Lyon;David W. Meyer

  • Design, synthesis, and evaluation of a novel pyrrolobenzodiazepine DNA-interactive agent with highly efficient cross-linking ability and potent cytotoxicity.

    Stephen J. Gregson;Philip W. Howard;John A. Hartley;Natalie A. Brooks

  • Targeting protein–protein interactions for therapeutic intervention: a challenge for the future

    Giovanna Zinzalla;David E Thurston

  • Chemical approaches to the discovery and development of cancer therapies

    Stephen Neidle;David E. Thurston

  • Synthesis of DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepines (PBDs).

    Dyeison Antonow;David E Thurston

  • From Anthramycin to Pyrrolobenzodiazepine (PBD)-Containing Antibody-Drug Conjugates (ADCs).

    Julia Mantaj;Paul J. M. Jackson;Khondaker M. Rahman;David E. Thurston

  • Rational design of a highly efficient irreversible DNA interstrand cross-linking agent based on the pyrrolobenzodiazepine ring system

    D. Subhas Bose;Andrew S. Thompson;Jingshan Ching;John A. Hartley

  • Synthesis of Sequence-Selective C8-Linked Pyrrolo[2,1-c][1,4]benzodiazepine DNA Interstrand Cross-Linking Agents.

    David E. Thurston;D. Subhas Bose;Andrew S. Thompson;Philip W. Howard

  • SJG-136 (NSC 694501), a Novel Rationally Designed DNA Minor Groove Interstrand Cross-Linking Agent with Potent and Broad Spectrum Antitumor Activity: Part 1: Cellular Pharmacology, In vitro and Initial In vivo Antitumor Activity

    John A. Hartley;Victoria J. Spanswick;Natalie Brooks;Peter H. Clingen

  • Linker length modulates DNA cross-linking reactivity and cytotoxic potency of C8/C8' ether-linked C2-exo-unsaturated pyrrolo[2,1-c][1,4]benzodiazepine (PBD) dimers.

    Stephen J Gregson;Philip W Howard;Darren R Gullick;Anzu Hamaguchi

  • SYNTHESIS OF DNA-INTERACTIVE PYRROLO2,1-C1,4BENZODIAZEPINES

    Unknown

  • Effect of A-ring modifications on the DNA-binding behavior and cytotoxicity of pyrrolo[2,1-c][1,4]benzodiazepines.

    Thurston De;Bose Ds;Howard Pw;Jenkins Tc

  • Pyrrolo[1,4]benzodiazepine antitumor antibiotics: relationship of DNA alkylation and sequence specificity to the biological activity of natural and synthetic compounds.

    Laurence H. Hurley;Teri Reck;David E. Thurston;David R. Langley

  • Antibody structure and engineering considerations for the design and function of Antibody Drug Conjugates (ADCs).

    Ricarda M Hoffmann;Ben G T Coumbe;Ben G T Coumbe;Debra H Josephs;Silvia Mele

  • Chemistry and Pharmacology of Anticancer Drugs

    David E. Thurston

  • Design, synthesis, and biophysical and biological evaluation of a series of Pyrrolobenzodiazepine - Poly(N-methylpyrrole) conjugates

    Geoff Wells;Christopher R H Martin;Philip W Howard;Zara A Sands

  • A versatile and efficient synthesis of carbinolamine-containing pyrrolo[1,4]benzodiazepines via the cyclization of N-(2-aminobenzoyl)pyrrolidine-2-carboxaldehyde diethyl thioacetals: total synthesis of prothracarcin

    David R. Langley;David E. Thurston

  • The pyrrolobenzodiazepine dimer SJG-136 forms sequence-dependent intrastrand DNA cross-links and monoalkylated adducts in addition to interstrand cross-links.

    Khondaker M. Rahman;Andrew S. Thompson;Colin H. James;Mathangi Narayanaswamy

  • Structure of a covalent DNA minor groove adduct with a pyrrolobenzodiazepine dimer: evidence for sequence-specific interstrand cross-linking.

    Terence C. Jenkins;Laurence H. Hurley;Laurence H. Hurley;Stephen Neidle;Stephen Neidle;David E. Thurston;David E. Thurston

  • SJG-136 (NSC 694501), A Novel Rationally Designed DNA Minor Groove Interstrand Cross-Linking Agent with Potent and Broad Spectrum Antitumor Activity: Part 2: Efficacy Evaluations

    Michael C. Alley;Melinda G. Hollingshead;Christine M. Pacula-Cox;William R. Waud

  • Inhibition of bacteriophage T7 RNA polymerase in vitro transcription by DNA-binding pyrrolo[2,1-c][1,4]benzodiazepines.

    Madhu S. Puvvada;Stephen A. Forrow;John A. Hartley;Pauline Stephenson

Frequent Co-Authors

John A. Hartley
John A. Hartley University College London
Stephen Neidle
Stephen Neidle University College London
Lloyd R. Kelland
Lloyd R. Kelland University College London
Laurence H. Hurley
Laurence H. Hurley University of Arizona
Keith R. Fox
Keith R. Fox University of Southampton
Pier Giovanni Baraldi
Pier Giovanni Baraldi University of Ferrara
Sophia N. Karagiannis
Sophia N. Karagiannis King's College London
Gary N. Parkinson
Gary N. Parkinson University College London
Andrew Tutt
Andrew Tutt Institute of Cancer Research
Nicoletta Bianchi
Nicoletta Bianchi University of Ferrara

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Best Scientists Citing David E. Thurston

John A. Hartley

John A. Hartley

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Stephen Neidle

Stephen Neidle

University College London

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Nagula Shankaraiah

Nagula Shankaraiah

Indian Institute of Chemical Technology

Publications: 18

Peter D. Senter

Peter D. Senter

Seattle Genetics (United States)

Publications: 16

Marie-Paule Teulade-Fichou

Marie-Paule Teulade-Fichou

University of Paris-Saclay

Publications: 11

W. David Wilson

W. David Wilson

Georgia State University

Publications: 11

Laurence H. Hurley

Laurence H. Hurley

University of Arizona

Publications: 10

J. William Lown

J. William Lown

University of Alberta

Publications: 9

Herren Wu

Herren Wu

AstraZeneca (United Kingdom)

Publications: 9

Pier Giovanni Baraldi

Pier Giovanni Baraldi

University of Ferrara

Publications: 9

Christoph Rader

Christoph Rader

Scripps Research Institute

Publications: 8

David R. Liu

David R. Liu

Broad Institute

Publications: 8

Romeo Romagnoli

Romeo Romagnoli

University of Ferrara

Publications: 8

Alain Beck

Alain Beck

University of Strasbourg

Publications: 7

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Seik Weng Ng

University of Malaya

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Genentech

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