World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
55
Citations
10828
World Ranking
12124
National Ranking
685

Overview

Lloyd R. Kelland was affiliated with University College London in the United Kingdom. Their academic career included research activities primarily based at this institution.

Available records do not list specific recent papers, frequent co-authors, or notable publication venues associated with their work. Similarly, there is no detailed information on particular fields of study, subfields, or main research topics documented.

No book publications or awards attributed to Lloyd R. Kelland have been recorded. The absence of such data suggests a limited publicly accessible bibliographic and recognition footprint.

The researcher is deceased, and all information reflects a completed academic record without ongoing contributions.

Best Publications

  • Discovery and development of anticancer aptamers.

    Christopher R. Ireson;Lloyd R. Kelland

  • Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors

    M Read;RJ Harrison;B Romagnoli;FA Tanious

  • DT-Diaphorase Expression and Tumor Cell Sensitivity to 17-Allylamino,17-demethoxygeldanamycin, an Inhibitor of Heat Shock Protein 90

    Lloyd R. Kelland;Swee Y. Sharp;Paul M. Rogers;Timothy G. Myers

  • Preclinical perspectives on platinum resistance.

    Lloyd R. Kelland

  • A G-quadruplex-interactive potent small-molecule inhibitor of telomerase exhibiting in vitro and in vivo antitumor activity.

    Sharon M. Gowan;John R. Harrison;Lisa Patterson;Melanie Valenti

  • Platinum-based drugs in cancer therapy

    Lloyd R. Kelland;Nicholas P. Farrell

  • The relationships between glutathione, glutathione-S-transferase and cytotoxicity of platinum drugs and melphalan in eight human ovarian carcinoma cell lines

    P. Mistry;L. R. Kelland;G. Abel;S. Sidhar

  • Design, synthesis, and evaluation of a novel pyrrolobenzodiazepine DNA-interactive agent with highly efficient cross-linking ability and potent cytotoxicity.

    Stephen J. Gregson;Philip W. Howard;John A. Hartley;Natalie A. Brooks

  • The dose-rate effect in human tumour cells.

    G. Gordon Steel;Judith M. Deacon;Gillian M. Duchesne;Alan Horwich

  • 2,7-Disubstituted amidofluorenone derivatives as inhibitors of human telomerase.

    Philip J. Perry;Martin A. Read;Rhian T. Davies;Sharon M. Gowan

  • A new class of symmetric bisbenzimidazole-based DNA minor groove-binding agents showing antitumor activity.

    John Mann;Anne Baron;Yaw Opoku-Boahen;Eric Johansson

  • Potent inhibition of telomerase by small-molecule pentacyclic acridines capable of interacting with G-quadruplexes.

    Sharon M. Gowan;Robert Heald;Malcolm F. G. Stevens;Lloyd R. Kelland

  • Mini-review: discovery and development of platinum complexes designed to circumvent cisplatin resistance

    Lloyd R. Kelland;Swee Y. Sharp;Ciaran F. O’Neill;Florence I. Raynaud

  • Activation of the trans geometry in platinum antitumor complexes: a survey of the cytotoxicity of trans complexes containing planar ligands in murine L1210 and human tumor panels and studies on their mechanism of action.

    N Farrell;L R Kelland;J D Roberts;M Van Beusichem

  • BBR 3464: a novel triplatinum complex, exhibiting a preclinical profile of antitumor efficacy different from cisplatin.

    C Manzotti;G Pratesi;E Menta;R Di Domenico

  • Trisubstituted acridine derivatives as potent and selective telomerase inhibitors.

    R John Harrison;Javier Cuesta;Gianni Chessari;Martin A Read

  • Biological properties of ten human ovarian carcinoma cell lines: calibration in vitro against four platinum complexes.

    C A Hills;L R Kelland;G Abel;J Siracky

  • Antitumor properties of some 2-[(dimethylamino)methyl]phenylgold(III) complexes.

    Robert G. Buckley;Amanda M. Elsome;Simon P. Fricker;Graham R. Henderson

  • Ammine/amine platinum(IV) dicarboxylates: a novel class of platinum complex exhibiting selective cytotoxicity to intrinsically cisplatin-resistant human ovarian carcinoma cell lines.

    Lloyd R. Kelland;Barry A. Murrer;George Abel;Christen M. Giandomenico

  • Human telomerase inhibition by substituted acridine derivatives.

    R. John Harrison;Sharon M. Gowan;Lloyd R. Kelland;Stephen Neidle

  • Human Telomerase Inhibition by Regioisomeric Disubstituted Amidoanthracene-9,10-diones

    Philip J. Perry;Anthony P. Reszka;Alexis A. Wood;Martin A. Read

  • Reduced drug accumulation as a major mechanism of acquired resistance to cisplatin in a human ovarian carcinoma cell line: circumvention studies using novel platinum (II) and (IV) ammine/amine complexes.

    S. Y. Loh;P. Mistry;L. R. Kelland;G. Abel

  • 1,4- and 2,6-Disubstituted Amidoanthracene-9,10-dione Derivatives as Inhibitors of Human Telomerase

    Philip J. Perry;Sharon M. Gowan;Anthony P. Reszka;Paolo Polucci

  • A G-quadruplex telomere targeting agent produces p16-associated senescence and chromosomal fusions in human prostate cancer cells.

    Christopher M Incles;Christoph M Schultes;Helena Kempski;Heike Koehler

  • SJG-136 (NSC 694501), a Novel Rationally Designed DNA Minor Groove Interstrand Cross-Linking Agent with Potent and Broad Spectrum Antitumor Activity: Part 1: Cellular Pharmacology, In vitro and Initial In vivo Antitumor Activity

    John A. Hartley;Victoria J. Spanswick;Natalie Brooks;Peter H. Clingen

  • A Novel trans-Platinum Coordination Complex Possessing in Vitro and in Vivo Antitumor Activity

    Lloyd R. Kelland;Christopher F. J. Barnard;Kirste J. Mellish;Mervyn Jones

Frequent Co-Authors

Stephen Neidle
Stephen Neidle University College London
David E. Thurston
David E. Thurston King's College London
Florence I. Raynaud
Florence I. Raynaud Institute of Cancer Research
Paul Workman
Paul Workman Institute of Cancer Research
John A. Hartley
John A. Hartley University College London
Ian Judson
Ian Judson Institute of Cancer Research
Nicholas Farrell
Nicholas Farrell Virginia Commonwealth University
John R. Griffiths
John R. Griffiths University of Manchester
Richard J. Harrison
Richard J. Harrison University of Cambridge
Malcolm F. G. Stevens
Malcolm F. G. Stevens University of Nottingham

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Best Scientists Citing Lloyd R. Kelland