D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 59 Citations 10,789 413 World Ranking 6880 National Ranking 191

Overview

What is he best known for?

The fields of study he is best known for:

  • Organic chemistry
  • Enzyme
  • DNA

His main research concerns Stereochemistry, Platinum, Cisplatin, DNA and Adduct. His Stereochemistry research includes elements of Conformational isomerism, Molecule and Ligand. His Platinum research integrates issues from Crystallography, Crystal structure, Inorganic chemistry, Adsorption and Reactivity.

His Cisplatin study incorporates themes from Biochemistry, Intracellular, Oxaliplatin, Cytotoxicity and Biological activity. His DNA study integrates concerns from other disciplines, such as In vitro, Guanine and Amine gas treating. His biological study spans a wide range of topics, including Nucleotide excision repair, Enantiomer, Docking and Leaving group.

His most cited work include:

  • Biomimetic Hydroxyapatite–Drug Nanocrystals as Potential Bone Substitutes with Antitumor Drug Delivery Properties† (254 citations)
  • Mechanistic insight into the cellular uptake and processing of cisplatin 30 years after its approval by FDA (201 citations)
  • Current status of trans-platinum compounds in cancer therapy (170 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Stereochemistry, Platinum, Ligand, Medicinal chemistry and Cisplatin. His research in Stereochemistry intersects with topics in Conformational isomerism, Adduct, Guanine and DNA. His Platinum study which covers Molecule that intersects with Hydrazone.

His studies deal with areas such as Chelation, Diamine, Ring and Phenanthroline as well as Ligand. His Medicinal chemistry research includes themes of Olefin fiber, Ethylene, Photochemistry, Cationic polymerization and Nucleophile. In his research, Chaperone is intimately related to ATOX1, which falls under the overarching field of Cisplatin.

He most often published in these fields:

  • Stereochemistry (51.17%)
  • Platinum (48.12%)
  • Ligand (25.59%)

What were the highlights of his more recent work (between 2009-2020)?

  • Stereochemistry (51.17%)
  • Cisplatin (17.84%)
  • Platinum (48.12%)

In recent papers he was focusing on the following fields of study:

Giovanni Natile mostly deals with Stereochemistry, Cisplatin, Platinum, DNA and Biochemistry. Giovanni Natile combines subjects such as Adduct, Ligand, Reactivity and Cytotoxicity with his study of Stereochemistry. The various areas that Giovanni Natile examines in his Cisplatin study include Cancer cell, Glutathione, Oxaliplatin, ATOX1 and Cytotoxic T cell.

The study incorporates disciplines such as Crystallography, Photochemistry, Metal, Combinatorial chemistry and Nucleophile in addition to Platinum. The DNA study combines topics in areas such as Biophysics and Ligand. His Biochemistry research incorporates themes from Targeted drug delivery and Drug.

Between 2009 and 2020, his most popular works were:

  • Probing the interaction of cisplatin with the human copper chaperone Atox1 by solution and in-cell NMR spectroscopy. (97 citations)
  • Translocation of Platinum Anticancer Drugs by Human Copper ATPases ATP7A and ATP7B (57 citations)
  • Platinum(II) complexes with bioactive carrier ligands having high affinity for the translocator protein. (56 citations)

In his most recent research, the most cited papers focused on:

  • Organic chemistry
  • Enzyme
  • DNA

Giovanni Natile focuses on Stereochemistry, Cisplatin, Platinum, DNA and Biochemistry. Giovanni Natile interconnects Adduct, Ligand and Medicinal chemistry in the investigation of issues within Stereochemistry. His work carried out in the field of Adduct brings together such families of science as Crystallography, Nuclear magnetic resonance spectroscopy, Metal and Chemical shift.

The concepts of his Cisplatin study are interwoven with issues in Cancer cell, Oxaliplatin, Efflux, Cytotoxicity and Diamine. His Platinum research integrates issues from Combinatorial chemistry and Reducing agent. His DNA study combines topics from a wide range of disciplines, such as Nucleotide and Ligand.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Biomimetic Hydroxyapatite–Drug Nanocrystals as Potential Bone Substitutes with Antitumor Drug Delivery Properties†

Barbara Palazzo;Michele Iafisco;Mariarita Laforgia;Nicola Margiotta.
Advanced Functional Materials (2007)

375 Citations

Mechanistic insight into the cellular uptake and processing of cisplatin 30 years after its approval by FDA

Fabio Arnesano;Giovanni Natile.
Coordination Chemistry Reviews (2009)

303 Citations

Current status of trans-platinum compounds in cancer therapy

Giovanni Natile;Mauro Coluccia.
Coordination Chemistry Reviews (2001)

282 Citations

A trans-platinum complex showing higher antitumor activity than the cis congeners.

Mauro Coluccia;Anna Nassi;Francesco Loseto;Angela Boccarelli.
Journal of Medicinal Chemistry (1993)

253 Citations

Trans-Platinum Complexes in Cancer Therapy

Mauro Coluccia;Giovanni Natile.
Anti-cancer Agents in Medicinal Chemistry (2007)

191 Citations

Mechanistic and Stereochemical Investigation of Imino Ethers Formed by Alcoholysis of Coordinated Nitriles: X-ray Crystal Structures of cis- and trans-Bis(1-imino-1-methoxyethane)dichloroplatinum(II)

Renzo Cini;Paola A. Caputo;Francesco P. Intini;Giovanni Natile.
Inorganic Chemistry (1995)

145 Citations

Probing the interaction of cisplatin with the human copper chaperone Atox1 by solution and in-cell NMR spectroscopy.

Fabio Arnesano;Lucia Banci;Ivano Bertini;Isabella C. Felli.
Journal of the American Chemical Society (2011)

142 Citations

Five-coordinate alkene complexes of palladium(II) and platinum(II)

Vincenzo G. Albano;Giovanni Natile;Achille Panunzi.
Coordination Chemistry Reviews (1994)

137 Citations

DNA-protein cross-linking by trans-[PtCl2(E-iminoether)2]. A concept for activation of the trans geometry in platinum antitumor complexes

Olga Novakova;Jana Kasparkova;Jaroslav Malina;Giovanni Natile.
Nucleic Acids Research (2003)

127 Citations

Interaction between platinum complexes and a methionine motif found in copper transport proteins.

Fabio Arnesano;Simone Scintilla;Giovanni Natile.
Angewandte Chemie (2007)

126 Citations

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