D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 40 Citations 6,013 229 World Ranking 13010 National Ranking 456

Overview

What is he best known for?

The fields of study he is best known for:

  • Organic chemistry
  • Enzyme
  • Oxygen

Domenico Osella spends much of his time researching Stereochemistry, Electrochemistry, Molecule, Platinum and Medicinal chemistry. His specific area of interest is Stereochemistry, where Domenico Osella studies Nuclear magnetic resonance spectroscopy. Domenico Osella has researched Electrochemistry in several fields, including Redox, Organic chemistry, Electron transfer and Polymer chemistry.

His Molecule research is multidisciplinary, incorporating elements of Crystallography, Metal, Analytical chemistry, Computational chemistry and Chemical shift. His Platinum research includes elements of Prodrug, Lipophilicity and Moiety. His biological study spans a wide range of topics, including Yield, Hydrogen, Pentene, Photochemistry and Ethyl acetate.

His most cited work include:

  • On the mechanism of the antitumor activity of ferrocenium derivatives (206 citations)
  • Uptake of antitumor platinum(II)-complexes by cancer cells, assayed by inductively coupled plasma mass spectrometry (ICP-MS). (189 citations)
  • Water stability and cytotoxic activity relationship of a series of ferrocenium derivatives. ESR insights on the radical production during the degradation process. (144 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Stereochemistry, Crystallography, Medicinal chemistry, Molecule and Electrochemistry. Domenico Osella interconnects Alkyne, Platinum, Ligand and Cisplatin in the investigation of issues within Stereochemistry. His Crystallography study also includes

  • Ruthenium which is related to area like Photochemistry,
  • Inorganic compound which intersects with area such as Spin–lattice relaxation and Physical chemistry.

Domenico Osella combines subjects such as Reactivity and Catalysis with his study of Medicinal chemistry. His study in Molecule is interdisciplinary in nature, drawing from both Computational chemistry, Transition metal and Analytical chemistry. His Electrochemistry research incorporates elements of Inorganic chemistry, Redox and Organic chemistry.

He most often published in these fields:

  • Stereochemistry (30.45%)
  • Crystallography (17.65%)
  • Medicinal chemistry (16.61%)

What were the highlights of his more recent work (between 2012-2021)?

  • Prodrug (7.61%)
  • Cisplatin (13.15%)
  • Stereochemistry (30.45%)

In recent papers he was focusing on the following fields of study:

Domenico Osella mainly focuses on Prodrug, Cisplatin, Stereochemistry, Conjugate and Combinatorial chemistry. His research in Prodrug intersects with topics in Cancer cell, In vitro, Platinum and Efflux. His work deals with themes such as Adjuvant, Cancer research, IC50 and Pharmacology, which intersect with Cisplatin.

His Stereochemistry research integrates issues from Biological activity, Hydrolysis, Medicinal chemistry and Cytotoxicity. The various areas that Domenico Osella examines in his Combinatorial chemistry study include Nanoparticle, Organic chemistry and Niche. Domenico Osella combines subjects such as Molecule and Ligand with his study of Tandem mass spectrometry.

Between 2012 and 2021, his most popular works were:

  • Pros and cons of bifunctional platinum(IV) antitumor prodrugs: two are (not always) better than one (74 citations)
  • A New Entry to Asymmetric Platinum(IV) Complexes via Oxidative Chlorination (50 citations)
  • Antiproliferative activity of Pt(IV)-bis(carboxylato) conjugates on malignant pleural mesothelioma cells (46 citations)

In his most recent research, the most cited papers focused on:

  • Organic chemistry
  • Enzyme
  • Oxygen

Domenico Osella spends much of his time researching Stereochemistry, Prodrug, Cisplatin, Lipophilicity and Platinum. His primary area of study in Stereochemistry is in the field of Nuclear magnetic resonance spectroscopy. His studies in Prodrug integrate themes in fields like Oral administration and Glutamine.

His Cisplatin study frequently intersects with other fields, such as Biological activity. The concepts of his Lipophilicity study are interwoven with issues in DNA, Efflux, Cell growth and Cytotoxicity. His studies deal with areas such as Quantitative structure–activity relationship, Molecular interaction fields, Partial least squares regression, Hydrogen bond and Computational chemistry as well as Platinum.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

On the mechanism of the antitumor activity of ferrocenium derivatives

Domenico Osella;Marco Ferrali;Piero Zanello;Franco Laschi.
Inorganica Chimica Acta (2000)

295 Citations

Uptake of antitumor platinum(II)-complexes by cancer cells, assayed by inductively coupled plasma mass spectrometry (ICP-MS).

AnnaRita Ghezzi;Maurizio Aceto;Claudio Cassino;Elisabetta Gabano.
Journal of Inorganic Biochemistry (2004)

256 Citations

Water stability and cytotoxic activity relationship of a series of ferrocenium derivatives. ESR insights on the radical production during the degradation process.

Giovanni Tabbì;Claudio Cassino;Giorgio Cavigiolio;Donato Colangelo.
Journal of Medicinal Chemistry (2002)

201 Citations

Deoxyribonucleic acid (DNA) biosensors for environmental risk assessment and drug studies.

Graziana Bagni;Domenico Osella;Elena Sturchio;Marco Mascini.
Analytica Chimica Acta (2006)

150 Citations

Antiproliferative Pt(IV) complexes: synthesis, biological activity, and quantitative structure–activity relationship modeling

Paola Gramatica;Ester Papa;Mara Luini;Elena Monti.
Journal of Biological Inorganic Chemistry (2010)

123 Citations

Cytotoxicity of cis-platinum(II) conjugate models. The effect of chelating arms and leaving groups on cytotoxicity: a quantitative structure-activity relationship approach.

Elena Monti;Marzia Gariboldi;Alessandro Maiocchi;Emilio Marengo.
Journal of Medicinal Chemistry (2005)

98 Citations

The RP-HPLC measurement and QSPR analysis of logPo/w values of several Pt(II) complexes

James A. Platts;Steven P. Oldfield;Maria M. Reif;Alessandra Palmucci.
Journal of Inorganic Biochemistry (2006)

98 Citations

Inhibition of Stat3 increases doxorubicin sensitivity in a human metastatic breast cancer cell line.

Marzia B. Gariboldi;Raffaella Ravizza;Roberta Molteni;Domenico Osella.
Cancer Letters (2007)

97 Citations

Stepwise Reduction of Dinitrogen Occurring on a Divanadium Model Compound: A Synthetic, Structural, Magnetic, Electrochemical, and Theoretical Investigation on the [VNNV]n+ [n = 4−6] Based Complexes

Richard Ferguson;Euro Solari;Carlo Floriani;Domenico Osella.
Journal of the American Chemical Society (1997)

97 Citations

Electronic interactions in organometallic dimers. An electrochemical approach

Domenico Osella;Luciano Milone;Carlo Nervi;Mauro Ravera.
Journal of Organometallic Chemistry (1995)

92 Citations

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