Domenico Osella spends much of his time researching Stereochemistry, Electrochemistry, Molecule, Platinum and Medicinal chemistry. His specific area of interest is Stereochemistry, where Domenico Osella studies Nuclear magnetic resonance spectroscopy. Domenico Osella has researched Electrochemistry in several fields, including Redox, Organic chemistry, Electron transfer and Polymer chemistry.
His Molecule research is multidisciplinary, incorporating elements of Crystallography, Metal, Analytical chemistry, Computational chemistry and Chemical shift. His Platinum research includes elements of Prodrug, Lipophilicity and Moiety. His biological study spans a wide range of topics, including Yield, Hydrogen, Pentene, Photochemistry and Ethyl acetate.
The scientist’s investigation covers issues in Stereochemistry, Crystallography, Medicinal chemistry, Molecule and Electrochemistry. Domenico Osella interconnects Alkyne, Platinum, Ligand and Cisplatin in the investigation of issues within Stereochemistry. His Crystallography study also includes
Domenico Osella combines subjects such as Reactivity and Catalysis with his study of Medicinal chemistry. His study in Molecule is interdisciplinary in nature, drawing from both Computational chemistry, Transition metal and Analytical chemistry. His Electrochemistry research incorporates elements of Inorganic chemistry, Redox and Organic chemistry.
Domenico Osella mainly focuses on Prodrug, Cisplatin, Stereochemistry, Conjugate and Combinatorial chemistry. His research in Prodrug intersects with topics in Cancer cell, In vitro, Platinum and Efflux. His work deals with themes such as Adjuvant, Cancer research, IC50 and Pharmacology, which intersect with Cisplatin.
His Stereochemistry research integrates issues from Biological activity, Hydrolysis, Medicinal chemistry and Cytotoxicity. The various areas that Domenico Osella examines in his Combinatorial chemistry study include Nanoparticle, Organic chemistry and Niche. Domenico Osella combines subjects such as Molecule and Ligand with his study of Tandem mass spectrometry.
Domenico Osella spends much of his time researching Stereochemistry, Prodrug, Cisplatin, Lipophilicity and Platinum. His primary area of study in Stereochemistry is in the field of Nuclear magnetic resonance spectroscopy. His studies in Prodrug integrate themes in fields like Oral administration and Glutamine.
His Cisplatin study frequently intersects with other fields, such as Biological activity. The concepts of his Lipophilicity study are interwoven with issues in DNA, Efflux, Cell growth and Cytotoxicity. His studies deal with areas such as Quantitative structure–activity relationship, Molecular interaction fields, Partial least squares regression, Hydrogen bond and Computational chemistry as well as Platinum.
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On the mechanism of the antitumor activity of ferrocenium derivatives
Domenico Osella;Marco Ferrali;Piero Zanello;Franco Laschi.
Inorganica Chimica Acta (2000)
Uptake of antitumor platinum(II)-complexes by cancer cells, assayed by inductively coupled plasma mass spectrometry (ICP-MS).
AnnaRita Ghezzi;Maurizio Aceto;Claudio Cassino;Elisabetta Gabano.
Journal of Inorganic Biochemistry (2004)
Water stability and cytotoxic activity relationship of a series of ferrocenium derivatives. ESR insights on the radical production during the degradation process.
Giovanni Tabbì;Claudio Cassino;Giorgio Cavigiolio;Donato Colangelo.
Journal of Medicinal Chemistry (2002)
Deoxyribonucleic acid (DNA) biosensors for environmental risk assessment and drug studies.
Graziana Bagni;Domenico Osella;Elena Sturchio;Marco Mascini.
Analytica Chimica Acta (2006)
Antiproliferative Pt(IV) complexes: synthesis, biological activity, and quantitative structure–activity relationship modeling
Paola Gramatica;Ester Papa;Mara Luini;Elena Monti.
Journal of Biological Inorganic Chemistry (2010)
Cytotoxicity of cis-platinum(II) conjugate models. The effect of chelating arms and leaving groups on cytotoxicity: a quantitative structure-activity relationship approach.
Elena Monti;Marzia Gariboldi;Alessandro Maiocchi;Emilio Marengo.
Journal of Medicinal Chemistry (2005)
The RP-HPLC measurement and QSPR analysis of logPo/w values of several Pt(II) complexes
James A. Platts;Steven P. Oldfield;Maria M. Reif;Alessandra Palmucci.
Journal of Inorganic Biochemistry (2006)
Inhibition of Stat3 increases doxorubicin sensitivity in a human metastatic breast cancer cell line.
Marzia B. Gariboldi;Raffaella Ravizza;Roberta Molteni;Domenico Osella.
Cancer Letters (2007)
Stepwise Reduction of Dinitrogen Occurring on a Divanadium Model Compound: A Synthetic, Structural, Magnetic, Electrochemical, and Theoretical Investigation on the [VNNV]n+ [n = 4−6] Based Complexes
Richard Ferguson;Euro Solari;Carlo Floriani;Domenico Osella.
Journal of the American Chemical Society (1997)
Electronic interactions in organometallic dimers. An electrochemical approach
Domenico Osella;Luciano Milone;Carlo Nervi;Mauro Ravera.
Journal of Organometallic Chemistry (1995)
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