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Chemistry
Italy
2025

D-Index & Metrics

Chemistry

D-Index
100
Citations
39135
World Ranking
1266
National Ranking
23

Research.com Recognitions

  • 2025 - Research.com Chemistry in Italy Leader Award
  • 2022 - Research.com Chemistry in Italy Leader Award

Overview

Silvio Aime is affiliated with the University of Turin in Italy. Their research spans multiple disciplines, principally within medicine and materials science, with a notable focus on imaging techniques and material chemistry.

The scientist has authored numerous publications in prominent venues, with frequent contributions to:

  • Angewandte Chemie International Edition
  • Angewandte Chemie
  • Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
  • The Cambridge Structural Database
  • Cancers

Silvio Aime's work covers several main fields of study:

  • Medicine
  • Materials Science

Within these broader fields, key subfields include:

  • Radiology, Nuclear Medicine and Imaging
  • Materials Chemistry
  • Biophysics
  • Spectroscopy
  • Molecular Biology

The main topics addressed in their research include:

  • Advanced MRI Techniques and Applications
  • Lanthanide and Transition Metal Complexes
  • Advanced NMR Techniques and Applications
  • Electron Spin Resonance Studies
  • MRI in cancer diagnosis
  • Magnetism in coordination complexes
  • Nanoplatforms for cancer theranostics

Frequent coauthors collaborating with Silvio Aime are:

  • Eleonora Cavallari
  • Carla Carrera
  • Eliana Gianolio
  • Enza Di Gregorio
  • Giuseppe Ferrauto

Recent significant papers include:

  • Review and consensus recommendations on clinical APT-weighted imaging approaches at 3T: Application to brain tumors, 2022, published in Magnetic Resonance in Medicine
  • Rapid hyperpolarization and purification of the metabolite fumarate in aqueous solution, 2021, published in Proceedings of the National Academy of Sciences
  • Rare earth elements (REE) in biology and medicine, 2020, published in RENDICONTI LINCEI
  • Hydrogenative-PHIP polarized metabolites for biological studies, 2021, published in Magnetic Resonance Materials in Physics Biology and Medicine
  • Nanocarriers as Magic Bullets in the Treatment of Leukemia, 2020, published in Nanomaterials

Best Publications

  • Challenges for Molecular Magnetic Resonance Imaging

    Enzo Terreno;Daniela Delli Castelli;Alessandra Viale;Silvio Aime

  • Lanthanide(III) chelates for NMR biomedical applications

    Silvio Aime;Mauro Botta;Mauro Fasano;Enzo Terreno

  • Biodistribution of gadolinium-based contrast agents, including gadolinium deposition.

    Silvio Aime;Peter Caravan

  • Paramagnetic lanthanide(III) complexes as pH-sensitive chemical exchange saturation transfer (CEST) contrast agents for MRI applications.

    Silvio Aime;Alessandro Barge;Daniela Delli Castelli;Franco Fedeli

  • Conformational and Coordination Equilibria on DOTA Complexes of Lanthanide Metal Ions in Aqueous Solution Studied by 1H-NMR Spectroscopy

    Silvio Aime;Mauro Botta;Mauro Fasano;M. Paula M. Marques

  • Gd(III)-BASED CONTRAST AGENTS FOR MRI

    Silvio Aime;Mauro Botta;Enzo Terreno

  • NMR study of solution structures and dynamics of lanthanide(III) complexes of DOTA

    Silvio Aime;Mauro Botta;Giuseppe Ermondi

  • Insights into the use of paramagnetic Gd(III) complexes in MR-molecular imaging investigations.

    Silvio Aime;Claudia Cabella;Sebastiano Colombatto;Simonetta Geninatti Crich

  • The Selectivity of Reversible Oxy-Anion Binding in Aqueous Solution at a Chiral Europium and Terbium Center: Signaling of Carbonate Chelation by Changes in the Form and Circular Polarization of Luminescence Emission

    James I. Bruce;Rachel S. Dickins;Linda J. Govenlock;Thorfinnur Gunnlaugsson

  • Pushing the Sensitivity Envelope of Lanthanide-Based Magnetic Resonance Imaging (MRI) Contrast Agents for Molecular Imaging Applications

    Silvio Aime;Daniela Delli Castelli;Simonetta Geninatti Crich;Eliana Gianolio

  • High sensitivity lanthanide(III) based probes for MR-medical imaging

    S. Aime;S. Geninatti Crich;E. Gianolio;G.B. Giovenzana

  • Compartmentalization of a gadolinium complex in the apoferritin cavity: a route to obtain high relaxivity contrast agents for magnetic resonance imaging.

    Silvio Aime;Luca Frullano;Simonetta Geninatti Crich

  • Structural, Luminescence, and NMR Studies of the Reversible Binding of Acetate, Lactate, Citrate, and Selected Amino Acids to Chiral Diaqua Ytterbium, Gadolinium, and Europium Complexes

    Rachel S. Dickins;Silvio Aime;Andrei S. Batsanov;Andrew Beeby

  • pH-dependent modulation of relaxivity and luminescence in macrocyclic gadolinium and europium complexes based on reversible intramolecular sulfonamide ligation.

    Mark P. Lowe;David Parker;Ofer Reany;Silvio Aime

  • NMR, Relaxometric, and Structural Studies of the Hydration and Exchange Dynamics of Cationic Lanthanide Complexes of Macrocyclic Tetraamide Ligands

    Silvio Aime;Alessandro Barge;James I. Bruce;Mauro Botta

  • ParaHydrogen Induced Polarization of 13C carboxylate resonance in acetate and pyruvate.

    Francesca Reineri;Tommaso Boi;Silvio Aime

  • [Gd-AAZTA]-: a new structural entry for an improved generation of MRI contrast agents.

    Silvio Aime;Luisella Calabi;Camilla Cavallotti;Eliana Gianolio

  • Novel pH‐Reporter MRI Contrast Agents

    Silvio Aime;Daniela Delli Castelli;Enzo Terreno

  • Novel Contrast Agents for Magnetic Resonance Imaging. Synthesis and Characterization of the Ligand BOPTA and Its Ln(III) Complexes (Ln = Gd, La, Lu). X-ray Structure of Disodium (TPS-9-145337286-C-S)-[4-Carboxy-5,8,11-tris(carboxymethyl)-1-phenyl-2-oxa- 5,8,11-triazatridecan-13-oato(5-)]gadolinate(2-) in a Mixture with Its Enantiomer

    Fulvio Uggeri;Silvio Aime;Pier Lucio Anelli;Mauro Botta

  • PROTOTROPIC AND WATER-EXCHANGE PROCESSES IN AQUEOUS SOLUTIONS OF GD(III) CHELATES

    Silvio Aime;Mauro Botta;Mauro Fasano;Enzo Terreno

Frequent Co-Authors

Mauro Botta
Mauro Botta University of Eastern Piedmont Amadeo Avogadro
Enzo Terreno
Enzo Terreno University of Turin
Roberto Gobetto
Roberto Gobetto University of Turin
Eliana Gianolio
Eliana Gianolio University of Turin
Domenico Osella
Domenico Osella University of Eastern Piedmont Amadeo Avogadro
Mauro Fasano
Mauro Fasano University of Insubria
David Parker
David Parker Durham University
Giovanni Palmisano
Giovanni Palmisano Khalifa University
Gaetano Granozzi
Gaetano Granozzi University of Padua
Kenneth N. Raymond
Kenneth N. Raymond Lawrence Berkeley National Laboratory

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