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Valentina Gandin

Valentina Gandin

D-Index & Metrics

Chemistry

D-Index
45
Citations
8827
World Ranking
16317
National Ranking
613

Overview

Valentina Gandin is affiliated with the University of Padua in Italy, with a research profile primarily focused within the fields of Chemistry and Medicine. Their work spans multiple subfields including Organic Chemistry, Oncology, Materials Chemistry, Molecular Biology, and Inorganic Chemistry.

Their research topics cover a breadth of areas such as:

  • Metal complexes synthesis and properties
  • Ferrocene Chemistry and Applications
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Synthesis and Characterization of Heterocyclic Compounds
  • Click Chemistry and Applications
  • Organometallic Complex Synthesis and Catalysis

Gandin's publication record includes numerous contributions to specialized scientific journals. Frequent venues for their research dissemination include:

  • The Cambridge Structural Database
  • International Journal of Molecular Sciences
  • Dalton Transactions
  • European Journal of Medicinal Chemistry
  • Journal of Medicinal Chemistry

Recent papers authored or co-authored by Gandin demonstrate contributions to medicinal chemistry and anticancer research, including:

  • In vitro and in vivo anticancer activity of tridentate thiosemicarbazone copper complexes: Unravelling an unexplored pharmacological target (2020, European Journal of Medicinal Chemistry)
  • Optimized Red-Absorbing Dyes for Imaging and Sensing (2023, Journal of the American Chemical Society)
  • Are Pt(IV) Prodrugs That Release Combretastatin A4 True Multi-action Prodrugs? (2021, Journal of Medicinal Chemistry)
  • Easily Available, Amphiphilic Diiron Cyclopentadienyl Complexes Exhibit in Vitro Anticancer Activity in 2D and 3D Human Cancer Cells through Redox Modulation Triggered by CO Release (2021, Chemistry - A European Journal)
  • 1,2,4-Amino-triazine derivatives as pyruvate dehydrogenase kinase inhibitors: Synthesis and pharmacological evaluation (2023, European Journal of Medicinal Chemistry)

Their collaboration network includes frequent co-authors such as Michele De Franco, Cristina Marzano, Lorenzo Biancalana, Fabio Marchetti, and Maura Pellei, reflecting ongoing partnerships in chemistry and pharmacological studies.

Best Publications

  • Advances in copper complexes as anticancer agents.

    Carlo Santini;Maura Pellei;Valentina Gandin;Marina Porchia

  • Selenium compounds as therapeutic agents in cancer

    Aristi P. Fernandes;Valentina Gandin

  • Organic selenium compounds as potential chemotherapeutic agents for improved cancer treatment.

    Valentina Gandin;Prajakta Khalkar;Jeremy Braude;Aristi P. Fernandes

  • Cancer cell death induced by phosphine gold(I) compounds targeting thioredoxin reductase.

    Valentina Gandin;Aristi Potamitou Fernandes;Maria Pia Rigobello;Barbara Dani

  • Pt( iv ) derivatives of cisplatin and oxaliplatin with phenylbutyrate axial ligands are potent cytotoxic agents that act by several mechanisms of action

    Raji Raveendran;Jeremy Phillip Braude;Ezequiel Wexselblatt;Vojtech Novohradsky

  • Synthesis, characterization, and in vitro antitumor properties of tris(hydroxymethyl)phosphine copper(I) complexes containing the new bis(1,2,4-triazol-1-yl)acetate ligand.

    Cristina Marzano;Maura Pellei;Davide Colavito;Simone Alidori

  • Triple action Pt(IV) derivatives of cisplatin: a new class of potent anticancer agents that overcome resistance

    Emanuele Petruzzella;Roman Sirota;Irene Solazzo;Valentina Gandin

  • In vitro antitumor activity of the water soluble copper(I) complexes bearing the tris(hydroxymethyl)phosphine ligand.

    Cristina Marzano;Valentina Gandin;Maura Pellei;Davide Colavito

  • In vitro and in vivo anticancer activity of copper(I) complexes with homoscorpionate tridentate tris(pyrazolyl)borate and auxiliary monodentate phosphine ligands.

    Valentina Gandin;Francesco Tisato;Alessandro Dolmella;Maura Pellei

  • Selenium induces a multi-targeted cell death process in addition to ROS formation

    Marita Wallenberg;Sougat Misra;Agata M Wasik;Cristina Marzano

  • A Quadruple-Action Platinum(IV) Prodrug with Anticancer Activity Against KRAS Mutated Cancer Cell Lines.

    Emanuele Petruzzella;Jeremy Phillip Braude;Janice R. Aldrich-Wright;Valentina Gandin

  • In Vitro Antitumour Activity of Water Soluble Cu(I), Ag(I) and Au(I) Complexes Supported by Hydrophilic Alkyl Phosphine Ligands

    Carlo Santini;Maura Pellei;Grazia Papini;Barbara Morresi

  • Synthesis and biological activity of ester- and amide-functionalized imidazolium salts and related water-soluble coinage metal N-heterocyclic carbene complexes.

    Maura Pellei;Valentina Gandin;Marika Marinelli;Cristina Marzano

  • Selenium-containing chrysin and quercetin derivatives: attractive scaffolds for cancer therapy.

    Inês L Martins;Catarina Charneira;Valentina Gandin;João L Ferreira da Silva

  • In vitro and in vivo anticancer activity of tridentate thiosemicarbazone copper complexes: Unravelling an unexplored pharmacological target.

    Mauro Carcelli;Matteo Tegoni;Jennifer Bartoli;Cristina Marzano

  • Smart delivery of antitumoral platinum complexes from biomimetic hydroxyapatite nanocrystals

    Michele Iafisco;Michele Iafisco;Barbara Palazzo;Barbara Palazzo;Marco Marchetti;Nicola Margiotta

  • Treatment of human cancer cells with selenite or tellurite in combination with auranofin enhances cell death due to redox shift.

    Maria Pia Rigobello;Valentina Gandin;Alessandra Folda;Anna-Klara Rundlöf

  • Synthesis and in vitro antitumor activity of water soluble sulfonate- and ester-functionalized silver(I) N-heterocyclic carbene complexes

    Valentina Gandin;Maura Pellei;Marika Marinelli;Cristina Marzano

  • Optimized Red-Absorbing Dyes for Imaging and Sensing

    Unknown

  • Revisiting [PtCl2(cis-1,4-DACH)]: an underestimated antitumor drug with potential application to the treatment of oxaliplatin-refractory colorectal cancer

    Nicola Margiotta;Cristina Marzano;Valentina Gandin;Domenico Osella

  • Synthesis and structural characterization of copper(I) complexes bearing N-methyl-1,3,5-triaza-7-phosphaadamantane (mPTA): cytotoxic activity evaluation of a series of water soluble Cu(I) derivatives containing PTA, PTAH and mPTA ligands

    Marina Porchia;Franco Benetollo;Fiorenzo Refosco;Francesco Tisato

Frequent Co-Authors

Cristina Marzano
Cristina Marzano University of Padua
Giovanni Natile
Giovanni Natile University of Bari Aldo Moro
Dan Gibson
Dan Gibson Hebrew University of Jerusalem
Alberto Bindoli
Alberto Bindoli University of Padua
Michele Iafisco
Michele Iafisco National Research Council (CNR)
Norberto Roveri
Norberto Roveri University of Bologna
Domenico Osella
Domenico Osella University of Eastern Piedmont Amadeo Avogadro
Stefano Dall’Acqua
Stefano Dall’Acqua University of Padua
Viktor Brabec
Viktor Brabec Czech Academy of Sciences
Roberta Seraglia
Roberta Seraglia National Research Council (CNR)

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