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Gérard Jaouen

Gérard Jaouen

D-Index & Metrics

Chemistry

D-Index
70
Citations
18742
World Ranking
5815
National Ranking
190

Research.com Recognitions

  • 2014 - Member of the European Academy of Sciences
  • 2012 - Member of Academia Europaea
  • 2002 - Centenary Prize, Royal Society of Chemistry (UK)

Overview

Gérard Jaouen is affiliated with Chimie ParisTech in France and has an extensive research portfolio primarily focused on the chemistry of ferrocene and metal complexes. Their work spans several intersecting fields, including Chemistry, Medicine, and Materials Science, with key contributions in Organic Chemistry, Oncology, and Materials Chemistry.

Their research topics cover a broad array of areas:

  • Ferrocene Chemistry and Applications
  • Metal complexes synthesis and properties
  • Synthesis and Biological Evaluation
  • Click Chemistry and Applications
  • Dendrimers and Hyperbranched Polymers
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography

Gérard Jaouen has co-authored multiple papers with several frequent collaborators, including Pascal Pigeon, Michael J. McGlinchey, Élise Lepeltier, Catherine Passirani, and Anne Vessières.

Their published work appears in a variety of scientific venues, with repeated contributions to the International Journal of Pharmaceutics and The Cambridge Structural Database, as well as papers published in Cancers, Molecules, and Coordination Chemistry Reviews.

Noteworthy recent publications include:

  • Multifaceted chemical behaviour of metallocene (M = Fe, Os) quinone methides. Their contribution to biology, 2020, Coordination Chemistry Reviews
  • How does ferrocene correlate with ferroptosis? Multiple approaches to explore ferrocene-appended GPX4 inhibitors as anticancer agents, 2024, Chemical Science
  • Ferrocifen Loaded Lipid Nanocapsules: A Promising Anticancer Medication against Multidrug Resistant Tumors, 2021, Cancers
  • Thioredoxin Reductase and Organometallic Complexes: A Pivotal System to Tackle Multidrug Resistant Tumors?, 2023, Cancers
  • Diversity-oriented synthesis and bioactivity evaluation of N-substituted ferrocifen compounds as novel antiproliferative agents against TNBC cancer cells, 2022, European Journal of Medicinal Chemistry

The scientist's career has been recognized through several affiliations and awards, including membership in the European Academy of Sciences since 2014 and Academia Europaea since 2012. They were also honored with the Centenary Prize from the Royal Society of Chemistry (UK) in 2002.

Best Publications

  • Ferrocifen type anti cancer drugs.

    Gérard Jaouen;Anne Vessières;Anne Vessières;Siden Top;Siden Top

  • Synthesis, biochemical properties and molecular modelling studies of organometallic specific estrogen receptor modulators (SERMs), the ferrocifens and hydroxyferrocifens: evidence for an antiproliferative effect of hydroxyferrocifens on both hormone-dependent and hormone-independent breast cancer cell lines.

    Siden Top;Anne Vessières;Guy Leclercq;Jacques Quivy

  • Bioorganometallics : biomolecules, labeling, medicine

    Gérard Jaouen

  • Ferrocene‐Mediated Proton‐Coupled Electron Transfer in a Series of Ferrocifen‐Type Breast‐Cancer Drug Candidates

    Elizabeth Hillard;Anne Vessières;Laurent Thouin;Gérard Jaouen

  • Bioorganometallic chemistry: Structural diversity of organometallic complexes with bioligands and molecular recognition studies of several supramolecular hosts with biomolecules, alkali-metal ions, and organometallic pharmaceuticals

    Richard H. Fish ,†,‡ and;Gérard Jaouen

  • Bioorganometallic chemistry: a future direction for transition metal organometallic chemistry?

    Gerard Jaouen;Anne Vessieres;Ian S. Butler

  • The first organometallic selective estrogen receptor modulators (SERMs) and their relevance to breast cancer

    Gérard Jaouen;Siden Top;Anne Vessières;Guy Leclercq

  • Medicinal organometallic chemistry

    Gérard Jaouen;Nils Metzler-Nolte

  • Studies on organometallic selective estrogen receptor modulators. (SERMs) Dual activity in the hydroxy-ferrocifen series

    Siden Top;Anne Vessières;Claude Cabestaing;Ioanna Laïos

  • Ferrocenyl hydroxytamoxifen: a prototype for a new range of oestradiol receptor site-directed cytotoxics

    Siden Top;Jie Tang;Anne Vessières;Danièle Carrez

  • Modification of the estrogenic properties of diphenols by the incorporation of ferrocene. Generation of antiproliferative effects in vitro.

    Anne Vessières;Siden Top;Pascal Pigeon;Elizabeth Hillard

  • Rhenium Carbonyl Complexes of .beta.-Estradiol Derivatives with High Affinity for the Estradiol Receptor: An Approach to Selective Organometallic Radiopharmaceuticals

    Siden Top;Hassane El Hafa;Anne Vessieres;Jacques Quivy

  • Electrochemical parameters and techniques in drug development, with an emphasis on quinones and related compounds

    Elizabeth Anne Hillard;Fabiane Caxico de Abreu;Danielle Cristhina Melo Ferreira;Gérard Jaouen

  • Ferrocenyl Quinone Methides as Strong Antiproliferative Agents: Formation by Metabolic and Chemical Oxidation of Ferrocenyl Phenols

    Didier Hamels;Patrick M. Dansette;Elizabeth A. Hillard;Siden Top

  • FACILE ROUTE TO FERROCIFEN, 1-4-(2-DIMETHYLAMINOETHOXY)-1-(PHENYL-2-FERROCENYL-BUT-1-ENE), FIRST ORGANOMETALLIC ANALOGUE OF TAMOXIFEN, BY THE MCMURRY REACTION

    Siden Top;Bénédicte Dauer;Jacqueline Vaissermann;Gérard Jaouen

  • Bioorganometallics: Future Trends in Drug Discovery, Analytical Chemistry, and Catalysis†,‡

    Elizabeth A. Hillard;Gérard Jaouen

  • Ferrocifens and ferrocifenols as new potential weapons against breast cancer

    Anh Nguyen;Anne Vessières;Elisabeth A. Hillard;Siden Top

  • Facile syntheses of optically active 2-substituted indanones, indanols, tetralones, and tetralols via their chromium tricarbonyl complexes

    Gerard Jaouen;Andre Meyer

  • New paradigms for synthetic pathways inspired by bioorganometallic chemistry

    Gérard Jaouen;Siden Top;Anne Vessières;Roger Alberto

  • Metal complex SERMs (selective oestrogen receptor modulators). The influence of different metal units on breast cancer cell antiproliferative effects

    Anne Vessières;Siden Top;Wolfgang Beck;Elizabeth Hillard

  • Ferrocifen Type Anticancer Drugs

    Gerard Jaouen;Anne Vessieres;Siden Top

Frequent Co-Authors

Anne Vessières
Anne Vessières Université Paris Cité
Siden Top
Siden Top Chimie ParisTech
Michael J. McGlinchey
Michael J. McGlinchey University College Dublin
Ian S. Butler
Ian S. Butler McGill University
Christian Amatore
Christian Amatore École Normale Supérieure
Domenico Osella
Domenico Osella University of Eastern Piedmont Amadeo Avogadro
Patrick M. Dansette
Patrick M. Dansette Université Paris Cité
Helge Müller-Bunz
Helge Müller-Bunz University College Dublin
Alberto Bindoli
Alberto Bindoli University of Padua
Jean-Paul Mornon
Jean-Paul Mornon Sorbonne University

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