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Akihiro Yachie

Akihiro Yachie

D-Index & Metrics

Immunology

D-Index
70
Citations
18868
World Ranking
2401
National Ranking
92

Overview

Akihiro Yachie is affiliated with Kanazawa University in Japan and has contributed extensively to research in medicine and biochemistry, genetics, and molecular biology. Their scholarly output includes a focus on molecular biology, surgery, hematology, genetics, and immunology.

Their main research topics encompass:

  • Inflammasome and immune disorders
  • Kawasaki Disease and coronary complications
  • Autoimmune and inflammatory disorders research
  • Renal diseases and glomerulopathies
  • Vasculitis and related conditions
  • Heme Oxygenase-1 and carbon monoxide
  • Genomics and rare diseases

Among their recent papers are:

  • Heme Oxygenase-1 Deficiency and Oxidative Stress: A Review of 9 Independent Human Cases and Animal Models, 2021, International Journal of Molecular Sciences
  • Transferrin receptor 1 is a cellular receptor for human heme-albumin, 2020, Communications Biology
  • Six years' accomplishment of the Initiative on Rare and Undiagnosed Diseases: nationwide project in Japan to discover causes, mechanisms, and cures, 2022, Journal of Human Genetics
  • Pathogenic roles and diagnostic utility of interleukin-18 in autoinflammatory diseases, 2022, Frontiers in Immunology
  • Comparison of serum cytokine profiles in macrophage activation syndrome complicating different background rheumatic diseases in children, 2020, Lara D. Veeken

Yachie collaborates frequently with the following coauthors:

  • Masaki Shimizu
  • Mao Mizuta
  • Natsumi Inoue
  • Taizo Wada
  • Tomohiro Koga

Their work is published repeatedly in several key venues, including:

  • Lara D. Veeken
  • Pediatrics International
  • International Journal of Hematology
  • Journal of Human Genetics
  • Frontiers in Immunology

Best Publications

  • Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency

    Akihiro Yachie;Yo Niida;Taizo Wada;Noboru Igarashi

  • Human Tyrosine Kinase 2 Deficiency Reveals Its Requisite Roles in Multiple Cytokine Signals Involved in Innate and Acquired Immunity

    Yoshiyuki Minegishi;Masako Saito;Tomohiro Morio;Ken Watanabe

  • Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood.

    T Miyawaki;T Uehara;R Nibu;T Tsuji

  • Involvement of Reactive Oxygen Intermediates in Spontaneous and CD95(Fas/APO-1)–Mediated Apoptosis of Neutrophils

    Yoshihito Kasahara;Kazuyuki Iwai;Akihiro Yachie;Kunio Ohta

  • Differential expression of bcl-2 and susceptibility to anti-Fas-mediated cell death in peripheral blood lymphocytes, monocytes, and neutrophils

    Kazuyuki Iwai;Toshio Miyawaki;Takenori Takizawa;Akihiro Konno

  • Proposed guidelines for diagnosing chronic active epstein-barr virus infection

    Motohiko Okano;Keisei Kawa;Hiroshi Kimura;Akihiro Yachie

  • Prognostic Factors for Chronic Active Epstein-Barr Virus Infection

    Hiroshi Kimura;Tsuneo Morishima;Hirokazu Kanegane;Shouichi Ohga

  • Heme oxygenase-1 deficiency: the first autopsy case.

    Atsuhiro Kawashima;Yoshio Oda;Akihiro Yachie;Shoichi Koizumi

  • Distinct cytokine profiles of systemic-onset juvenile idiopathic arthritis-associated macrophage activation syndrome with particular emphasis on the role of interleukin-18 in its pathogenesis

    Masaki Shimizu;Tadafumi Yokoyama;Keiko Yamada;Hisashi Kaneda

  • Differential cellular targets of Epstein-Barr virus (EBV) infection between acute EBV-associated hemophagocytic lymphohistiocytosis and chronic active EBV infection.

    Yoshihito Kasahara;Akihiro Yachie;Kenkichi Takei;Chiharu Kanegane

  • Interleukin-18 for predicting the development of macrophage activation syndrome in systemic juvenile idiopathic arthritis.

    Masaki Shimizu;Yasuo Nakagishi;Natsumi Inoue;Mao Mizuta

  • Human heme oxygenase-1 deficiency presenting with hemolysis, nephritis, and asplenia.

    Nita Radhakrishnan;Satya Prakash Yadav;Anupam Sachdeva;Praveen K. Pruthi

  • The acute phase nature of interleukin 6: studies in Kawasaki disease and other febrile illnesses.

    Y Ueno;N Takano;H Kanegane;T Yokoi

  • Tocilizumab masks the clinical symptoms of systemic juvenile idiopathic arthritis-associated macrophage activation syndrome: the diagnostic significance of interleukin-18 and interleukin-6.

    Masaki Shimizu;Yasuo Nakagishi;Kazuko Kasai;Yuichi Yamasaki

  • Tubular injury as a cardinal pathologic feature in human heme oxygenase-1 deficiency.

    Kazuhide Ohta;Akihiro Yachie;Kayoko Fujimoto;Hisashi Kaneda

  • Sustained elevation of serum interleukin-18 and its association with hemophagocytic lymphohistiocytosis in XIAP deficiency.

    Taizo Wada;Hirokazu Kanegane;Kazuhide Ohta;Fumiyo Katoh

  • Distinct subsets of patients with systemic juvenile idiopathic arthritis based on their cytokine profiles.

    Masaki Shimizu;Yasuo Nakagishi;Akihiro Yachie

  • Regulation of B cell differentiation by T cell subsets defined with monoclonal OKT4 and OKT8 antibodies in human cord blood.

    A Yachie;T Miyawaki;T Nagaoki;T Yokoi

  • Cell type specific infection of Epstein-Barr virus (EBV) in EBV-associated hemophagocytic lymphohistiocytosis and chronic active EBV infection.

    Yoshihito Kasahara;Akihiro Yachie

  • Cytokine profile in adult-onset Still's disease: Comparison with systemic juvenile idiopathic arthritis

    Natsumi Inoue;Masaki Shimizu;Shinichiro Tsunoda;Mitsuhiro Kawano

  • Characterization of T-cell repertoire of the bone marrow in immune-mediated aplastic anemia: evidence for the involvement of antigen-driven T-cell response in cyclosporine-dependent aplastic anemia

    Weihua Zeng;Shinji Nakao;Hideyuki Takamatsu;Akihiro Yachie

Frequent Co-Authors

Kazunaga Agematsu
Kazunaga Agematsu Shinshu University
Hirokazu Kanegane
Hirokazu Kanegane Tokyo Medical and Dental University
Kiyoshi Migita
Kiyoshi Migita Fukushima Medical University
Toshio Miyawaki
Toshio Miyawaki University of Toyama
Tomohiro Morio
Tomohiro Morio Institute of Science Tokyo
Shinji Nakao
Shinji Nakao Kanazawa University
Atsushi Kawakami
Atsushi Kawakami Nagasaki University
Masakazu Yamagishi
Masakazu Yamagishi Osaka University of Human Sciences
Kohsuke Imai
Kohsuke Imai Tokyo Medical and Dental University
Katsumi Eguchi
Katsumi Eguchi Nagasaki University

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