2026 Kazunaga Agematsu: Immunology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Immunology	46	4611	4268	176	157	153	8571

Overview

Kazunaga Agematsu is affiliated with Shinshu University in Japan and has contributed to research primarily in the fields of Immunology and Microbiology as well as Medicine. Their publication record includes work related to subfields such as Immunology, Molecular Biology, Surgery, Hematology, and Pulmonary and Respiratory Medicine.

Their research focuses on multiple interconnected topics including:

Inflammasome and immune disorders
Interferon and immune responses
Immunodeficiency and Autoimmune Disorders
Immune Response and Inflammation
IL-33, ST2, and ILC Pathways
Eosinophilic Esophagitis
Kawasaki Disease and Coronary Complications

Agematsu has published in various scientific venues, including:

Scientific Reports
PubMed
Journal of Investigational Allergology and Clinical Immunology
Annals of the Rheumatic Diseases
Transplant Immunology

Notable recent papers by Agematsu include:

"KN3014, a piperidine-containing small compound, inhibits auto-secretion of IL-1β from PBMCs in a patient with Muckle-Wells syndrome," 2020, Scientific Reports
"[AN ADULT CASE OF PERIODIC FEVER, APHTHOUS STOMATITIS, PHARYNGITIS, AND ADENITIS (PFAPA) SYNDROME DEVELOPED IN CHILDHOOD AND DIAGNOSED AFTER PROGRESS MORE THAN 30 YEARS].," 2020, PubMed
"Early-Onset Inflammatory Bowel Disease Caused by Mutations in the X-Linked Gene IL2RG," 2020, Journal of Investigational Allergology and Clinical Immunology
"SAT0527 COMBINED EFFECT OF COMMON VARIANTS IN EXON 2 OR EXON 3 AND A PATHOGENIC MUTATION IN EXON 10 OF THE MEDITERRANEAN FEVER GENE ON INFLAMMASOME ACTIVATION IN JAPANESE PATIENTS WITH FAMILIAL MEDITERRANEAN FEVER," 2020, Annals of the Rheumatic Diseases
"Unrelated cord blood transplantation using minimal-intensity conditioning in a 1.5-month-old infant with X-linked severe combined immunodeficiency," 2024, Transplant Immunology

Frequent collaborators include researchers such as Tomonari Shigemura, Tomohiro Koga, Atsushi Kawakami, Akihiro Yachie, and Kiyoshi Migita. These coauthor relationships reflect a collaborative approach across overlapping fields related to immune function and inflammatory diseases.

Best Publications

Human Tyrosine Kinase 2 Deficiency Reveals Its Requisite Roles in Multiple Cytokine Signals Involved in Innate and Acquired Immunity

Yoshiyuki Minegishi;Masako Saito;Tomohiro Morio;Ken Watanabe

804
Citations
CD27: a memory B-cell marker

Unknown

437
Citations
B cell subpopulations separated by CD27 and crucial collaboration of CD27+ B cells and helper T cells in immunoglobulin production

Kazunaga Agematsu;Haruo Nagumo;Fen Chun Yang;Takayuki Nakazawa

380
Citations
Molecular explanation for the contradiction between systemic Th17 defect and localized bacterial infection in hyper-IgE syndrome

Yoshiyuki Minegishi;Masako Saito;Masayuki Nagasawa;Hidetoshi Takada

326
Citations
Regulation of Aged Humoral Immune Defense against Pneumococcal Bacteria by IgM Memory B Cell

Yuhui Shi;Takashi Yamazaki;Yoshio Okubo;Yoshio Uehara

321
Citations
Generation of Plasma Cells From Peripheral Blood Memory B Cells: Synergistic Effect of Interleukin-10 and CD27/CD70 Interaction

Kazunaga Agematsu;Haruo Nagumo;Haruo Nagumo;Haruo Nagumo;Yumiko Oguchi;Yumiko Oguchi;Yumiko Oguchi;Takayuki Nakazawa;Takayuki Nakazawa;Takayuki Nakazawa

312
Citations
Absence of IgD-CD27(+) memory B cell population in X-linked hyper-IgM syndrome.

Kazunaga Agematsu;Haruo Nagumo;Koji Shinozaki;Sho Hokibara

293
Citations
CD27-CD70 interactions regulate B-cell activation by T cells.

Tetsuji Kobata;Serge Jacquot;Stacy Kozlowski;Kazunaga Agematsu

281
Citations
Functional analysis of human memory B-cell subpopulations: IgD+CD27+ B cells are crucial in secondary immune response by producing high affinity IgM.

Yuhui Shi;Kazunaga Agematsu;Hans D Ochs;Kazuo Sugane

234
Citations
Mechanism of Hypergammaglobulinemia by HIV Infection: Circulating Memory B-Cell Reduction with Plasmacytosis

Hisashi Nagase;Kazunaga Agematsu;Kiyoshi Kitano;Masaya Takamoto

189
Citations
Absence of memory B cells in patients with common variable immunodeficiency.

Kazunaga Agematsu;Takeshi Futatani;Sho Hokibara;Norimoto Kobayashi

180
Citations
Theophylline accelerates human granulocyte apoptosis not via phosphodiesterase inhibition.

K. Yasui;B. Hu;T. Nakazawa;K. Agematsu

178
Citations
Clinical and laboratory features of fatal rapidly progressive interstitial lung disease associated with juvenile dermatomyositis

Norimoto Kobayashi;Shunichiro Takezaki;Ichiro Kobayashi;Naomi Iwata

164
Citations
Neutrophil-specific granule deficiency: homozygous recessive inheritance of a frameshift mutation in the gene encoding transcription factor CCAAT/enhancer binding protein--epsilon.

Adrian F. Gombart;Masaaki Shiohara;Scott H. Kwok;Kazunaga Agematsu

159
Citations
Defective IL-10 signaling in hyper-IgE syndrome results in impaired generation of tolerogenic dendritic cells and induced regulatory T cells

Masako Saito;Masayuki Nagasawa;Hidetoshi Takada;Toshiro Hara

158
Citations
Novel mutations in a Japanese patient with CD19 deficiency

H Kanegane;K Agematsu;T Futatani;M M Sira

155
Citations
Genetic defect in human X-linked agammaglobulinemia impedes a maturational evolution of pro-B cells into a later stage of pre-B cells in the B-cell differentiation pathway.

Keiko Nomura;Hirokazu Kanegane;Hajime Karasuyama;Satoshi Tsukada

131
Citations
Familial Mediterranean fever: genotype-phenotype correlations in Japanese patients.

Kiyoshi Migita;Kazunaga Agematsu;Masahide Yazaki;Fumiaki Nonaka

130
Citations
Quantification of κ-deleting recombination excision circles in Guthrie cards for the identification of early B-cell maturation defects

Noriko Nakagawa;Kohsuke Imai;Hirokazu Kanegane;Hiroki Sato

127
Citations
CD27/CD70 interaction directly drives B cell IgG and IgM synthesis

Kazunaga Agematsu;Tetsuji Kobata;Feng‐Chun ‐C Yang;Takayuki Nakazawa

125
Citations
Detection of Bruton's tyrosine kinase mutations in hypogammaglobulinaemic males registered as common variable immunodeficiency (CVID) in the Japanese Immunodeficiency Registry

H Kanegane;S Tsukada;T Iwata;T Futatani

115
Citations
CD27/CD70 interaction directly induces natural killer cell killing activity.

F.C. Yang;K. Agematsu;T. Nakazawa;T. Mori

102
Citations

Frequent Co-Authors

Kiyoshi Migita Fukushima Medical University

Akihiro Yachie Kanazawa University

Atsushi Kawakami Nagasaki University

Katsumi Eguchi Nagasaki University

Toshio Miyawaki University of Toyama

Hirokazu Kanegane Tokyo Medical and Dental University

Chikao Morimoto Juntendo University

Tetsuji Kobata Tokyo Medical and Dental University

Koh-ichiro Yoshiura Nagasaki University

Osamu Ohara Chiba University

External Links

Personal website of Kazunaga Agematsu

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