Kohsuke Imai

Overview

Best Publications

• Human Tyrosine Kinase 2 Deficiency Reveals Its Requisite Roles in Multiple Cytokine Signals Involved in Innate and Acquired Immunity

  Yoshiyuki Minegishi;Masako Saito;Tomohiro Morio;Ken Watanabe

  804
  Citations

• Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination.

  Kohsuke Imai;Geir Slupphaug;Wen I. Lee;Wen I. Lee;Patrick Revy

  764
  Citations

• Autoantibodies neutralizing type I IFNs are present in ~ 4% of uninfected individuals over 70 years old and account for ~ 20% of COVID-19 deaths.

  Paul Bastard;Adrian Gervais;Adrian Gervais;Tom Le Voyer;Tom Le Voyer;Jérémie Rosain;Jérémie Rosain

  592
  Citations

• Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study.

  Tanya I Coulter;Anita Chandra;Chris M Bacon;Judith Babar

  468
  Citations

• Clinical course of patients with WASP gene mutations

  Kohsuke Imai;Tomohiro Morio;Yi Zhu;Yinzhu Jin

  466
  Citations

• Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4–insufficient subjects

  Charlotte Schwab;Annemarie Gabrysch;Peter Olbrich;Virginia Patiño

  443
  Citations

• AID mutant analyses indicate requirement for class-switch-specific cofactors

  Van-Thanh Ta;Hitoshi Nagaoka;Nadia Catalan;Anne Durandy

  382
  Citations

• Clinical and immunologic phenotype associated with activated phosphoinositide 3-kinase δ syndrome 2: A cohort study

  Elodie Elkaim;Elodie Elkaim;Benedicte Neven;Benedicte Neven;Benedicte Neven;Julie Bruneau;Julie Bruneau;Kanako Mitsui-Sekinaka

  283
  Citations

• WASP (Wiskott-Aldrich syndrome protein) gene mutations and phenotype.

  Kohsuke Imai;Shigeaki Nonoyama;Hans D. Ochs

  166
  Citations

• Hyper-IgM syndrome type 4 with a B lymphocyte–intrinsic selective deficiency in Ig class-switch recombination

  Kohsuke Imai;Nadia Catalan;Alessandro Plebani;László Maródi

  163
  Citations

• Multicenter experience in hematopoietic stem cell transplantation for serious complications of common variable immunodeficiency

  Claudia Wehr;Andrew R. Gennery;Caroline Lindemans;Ansgar Schulz

  159
  Citations

• Molecular and Virological Evidence of Viral Activation From Chromosomally Integrated Human Herpesvirus 6A in a Patient With X-Linked Severe Combined Immunodeficiency

  Akifumi Endo;Ken Watanabe;Tamae Ohye;Kyoko Suzuki

  154
  Citations

• Hematopoietic stem cell transplantation in patients with gain-of-function signal transducer and activator of transcription 1 mutations

  Jennifer W. Leiding;Satoshi Okada;David Hagin;Mario Abinun;Mario Abinun

  152
  Citations

• Repair of U/G and U/A in DNA by UNG2-associated repair complexes takes place predominantly by short-patch repair both in proliferating and growth-arrested cells

  Mansour Akbari;Marit Otterlei;Javier Peña-Diaz;Per Arne Aas

  141
  Citations

• SARS-CoV-2-related MIS-C: A key to the viral and genetic causes of Kawasaki disease?

  Vanessa Sancho-Shimizu;Petter Brodin;Aurélie Cobat;Aurélie Cobat;Aurélie Cobat;Catherine M Biggs

  139
  Citations

• B cells from hyper-IgM patients carrying UNG mutations lack ability to remove uracil from ssDNA and have elevated genomic uracil

  Bodil Kavli;Sonja Andersen;Marit Otterlei;Nina B. Liabakk

  138
  Citations

• Abnormal hematopoiesis and autoimmunity in human subjects with germline IKZF1 mutations.

  Akihiro Hoshino;Satoshi Okada;Kenichi Yoshida;Naonori Nishida

  137
  Citations

• Identification of Severe Combined Immunodeficiency by T-Cell Receptor Excision Circles Quantification Using Neonatal Guthrie Cards

  Yoichi Morinishi;Kohsuke Imai;Noriko Nakagawa;Hiroki Sato

  136
  Citations

• Flow cytometry-based diagnosis of primary immunodeficiency diseases

  Hirokazu Kanegane;Akihiro Hoshino;Tsubasa Okano;Takahiro Yasumi

  136
  Citations

• Analysis of class switch recombination and somatic hypermutation in patients affected with autosomal dominant hyper-IgM syndrome type 2

  Kohsuke Imai;Yi Zhu;Patrick Revy;Tomohiro Morio

  129
  Citations

• The Block in Immunoglobulin Class Switch Recombination Caused by Activation-Induced Cytidine Deaminase Deficiency Occurs Prior to the Generation of DNA Double Strand Breaks in Switch μ Region

  Nadia Catalan;Françoise Selz;Kohsuke Imai;Patrick Revy

  125
  Citations