D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 42 Citations 10,228 100 World Ranking 17016 National Ranking 1351

Overview

What is he best known for?

The fields of study he is best known for:

  • Amino acid
  • Biochemistry
  • Antibody

P. Anton van der Merwe mostly deals with Cell biology, T-cell receptor, Receptor, T cell and Molecular biology. The Cell biology study combines topics in areas such as Cell surface receptor and MHC class I. His T-cell receptor research includes themes of Biophysics and Major histocompatibility complex.

His Receptor research integrates issues from Plasma protein binding and Antigen. The study incorporates disciplines such as CD8, Leukocyte Immunoglobulin-like Receptor B1, Cytoskeleton and Protein tyrosine phosphatase in addition to T cell. When carried out as part of a general Molecular biology research project, his work on Glycoprotein is frequently linked to work in CD48, therefore connecting diverse disciplines of study.

His most cited work include:

  • A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts. (624 citations)
  • Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G (438 citations)
  • Molecular Interactions Mediating T Cell Antigen Recognition (431 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include T-cell receptor, Receptor, Cell biology, T cell and Biophysics. His T-cell receptor research is multidisciplinary, relying on both Signal transduction and Major histocompatibility complex, Antigen. The concepts of his Receptor study are interwoven with issues in Plasma protein binding and Cytoplasm.

His research in Cell biology focuses on subjects like Cell adhesion, which are connected to Selectin. His T cell study integrates concerns from other disciplines, such as CD58, Molecular biology, Reaction rate constant and CD8. His Biophysics research is multidisciplinary, incorporating elements of Jurkat cells, Cell surface receptor and Biochemistry.

He most often published in these fields:

  • T-cell receptor (46.24%)
  • Receptor (39.78%)
  • Cell biology (38.71%)

What were the highlights of his more recent work (between 2013-2021)?

  • T-cell receptor (46.24%)
  • Receptor (39.78%)
  • Biophysics (29.03%)

In recent papers he was focusing on the following fields of study:

His main research concerns T-cell receptor, Receptor, Biophysics, T cell and Antigen. His T-cell receptor study combines topics in areas such as Kinetic proofreading, HEK 293 cells, Cell biology, Molecular simulation and Major histocompatibility complex. His research integrates issues of Protein structure, Allosteric regulation and Immune system in his study of Cell biology.

His studies deal with areas such as Lymphatic system and Lymphatic Endothelium as well as Receptor. P. Anton van der Merwe has researched T cell in several fields, including CD8 and Tyrosine phosphorylation. His Antigen research includes elements of SH2 domain and Proto-oncogene tyrosine-protein kinase Src.

Between 2013 and 2021, his most popular works were:

  • Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis (103 citations)
  • Phenotypic models of T cell activation (99 citations)
  • An induced rebinding model of antigen discrimination (49 citations)

In his most recent research, the most cited papers focused on:

  • Amino acid
  • Biochemistry
  • Antibody

P. Anton van der Merwe focuses on Kinetic proofreading, Receptor, Biophysics, T-cell receptor and Peptide. His study in Kinetic proofreading is interdisciplinary in nature, drawing from both Peptide-MHC, Plasma protein binding, Lymphocyte activation and Immunology, Antigen. A large part of his Receptor studies is devoted to Ligand.

P. Anton van der Merwe has researched Biophysics in several fields, including Integrin, Biochemistry, Phagocytic cup and Second messenger system. In his works, P. Anton van der Merwe conducts interdisciplinary research on T-cell receptor and Mathematical model. In his study, which falls under the umbrella issue of Peptide, Binding site and Streptavidin is strongly linked to Supramolecular chemistry.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts.

Michael L Dustin;Michael W Olszowy;Amy D Holdorf;Jun Li.
Cell (1998)

827 Citations

The interaction properties of costimulatory molecules revisited.

Alison V. Collins;Douglas W. Brodie;Robert J.C. Gilbert;Andrea Iaboni.
Immunity (2002)

756 Citations

Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G

Mitsunori Shiroishi;Kouhei Tsumoto;Kimie Amano;Yasuo Shirakihara.
Proceedings of the National Academy of Sciences of the United States of America (2003)

600 Citations

Molecular Interactions Mediating T Cell Antigen Recognition

P. Anton van der Merwe;Simon J. Davis.
Annual Review of Immunology (2003)

567 Citations

2B4, the Natural Killer and T Cell Immunoglobulin Superfamily Surface Protein, Is a Ligand for CD48

Marion H. Brown;Kent Boles;P. Anton van der Merwe;Vinay Kumar.
Journal of Experimental Medicine (1998)

493 Citations

Mechanisms for T cell receptor triggering

P. Anton van der Merwe;Omer Dushek.
Nature Reviews Immunology (2011)

473 Citations

TCR binding to peptide-MHC stabilizes a flexible recognition interface.

Benjamin E. Willcox;George F. Gao;Jessica R. Wyer;John Edward Simon Durham Ladbury.
Immunity (1999)

370 Citations

T-cell receptor triggering is critically dependent on the dimensions of its peptide-MHC ligand.

Kaushik Choudhuri;David Wiseman;Marion H. Brown;Keith Gould.
Nature (2005)

353 Citations

Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition.

P.Anton van der Merwe;Simon J. Davis;Andrey S. Shaw;Michael L. Dustin.
Seminars in Immunology (2000)

313 Citations

The mast cell tumor necrosis factor α response to FimH-expressing Escherichia coli is mediated by the glycosylphosphatidylinositol-anchored molecule CD48

Ravi Malaviya;Zhimin Gao;Krishnan Thankavel;P. Anton van der Merwe.
Proceedings of the National Academy of Sciences of the United States of America (1999)

296 Citations

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