P. Anton van der Merwe

Overview

Best Publications

• A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts.

  Michael L Dustin;Michael W Olszowy;Amy D Holdorf;Jun Li

  891
  Citations

• The interaction properties of costimulatory molecules revisited.

  Alison V. Collins;Douglas W. Brodie;Robert J.C. Gilbert;Andrea Iaboni

  836
  Citations

• CD80 (B7-1) Binds Both CD28 and CTLA-4 with a Low Affinity and Very Fast Kinetics

  P A van der Merwe;D L Bodian;S Daenke;P Linsley

  700
  Citations

• Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G

  Mitsunori Shiroishi;Kouhei Tsumoto;Kimie Amano;Yasuo Shirakihara

  666
  Citations

• The kinetic-segregation model: TCR triggering and beyond

  S J Davis;P A van der Merwe

  604
  Citations

• Molecular Interactions Mediating T Cell Antigen Recognition

  P. Anton van der Merwe;Simon J. Davis

  601
  Citations

• Mechanisms for T cell receptor triggering

  P. Anton van der Merwe;Omer Dushek

  575
  Citations

• 2B4, the Natural Killer and T Cell Immunoglobulin Superfamily Surface Protein, Is a Ligand for CD48

  Marion H. Brown;Kent Boles;P. Anton van der Merwe;Vinay Kumar

  519
  Citations

• The structure and ligand interactions of CD2: implications for T-cell function

  S J Davis;P A van der Merwe

  518
  Citations

• Production of soluble alphabeta T-cell receptor heterodimers suitable for biophysical analysis of ligand binding.

  B E Willcox;G F Gao;Wyer;C A O'Callaghan

  517
  Citations

• T-cell receptor triggering is critically dependent on the dimensions of its peptide-MHC ligand.

  Kaushik Choudhuri;David Wiseman;Marion H. Brown;Keith Gould

  410
  Citations

• TCR binding to peptide-MHC stabilizes a flexible recognition interface.

  Benjamin E. Willcox;George F. Gao;Jessica R. Wyer;John Edward Simon Durham Ladbury

  380
  Citations

• Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition.

  P.Anton van der Merwe;Simon J. Davis;Andrey S. Shaw;Michael L. Dustin

  342
  Citations

• Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines

  Ji-Li Chen;Guillaume Stewart-Jones;Giovanna Bossi;Nikolai M. Lissin

  330
  Citations

• Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics.

  Michael I Barton;Stuart A MacGowan;Mikhail A Kutuzov;Omer Dushek

  315
  Citations

• The nature of molecular recognition by T cells

  Simon J. Davis;Shinji Ikemizu;Edward J. Evans;Lars Fugger

  306
  Citations

• The mast cell tumor necrosis factor α response to FimH-expressing Escherichia coli is mediated by the glycosylphosphatidylinositol-anchored molecule CD48

  Ravi Malaviya;Zhimin Gao;Krishnan Thankavel;P. Anton van der Merwe

  302
  Citations

• CDR3 loop flexibility contributes to the degeneracy of TCR recognition.

  Jean-Baptiste Reiser;Claudine Darnault;Claude Grégoire;Thomas Mosser

  302
  Citations

• Siglecs: a family of sialic-acid binding lectins.

  P R Crocker;E A Clark;M Filbin;S Gordon

  297
  Citations

• Transient intercellular adhesion: the importance of weak protein-protein interactions.

  P A van der Merwe;A N Barclay

  291
  Citations