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David S. Millington

David S. Millington

D-Index & Metrics

Biology and Biochemistry

D-Index
74
Citations
18705
World Ranking
5620
National Ranking
2670

Medicine

D-Index
73
Citations
17980
World Ranking
19675
National Ranking
9800

Overview

David S. Millington is affiliated with Duke University in the United States. Their research spans multiple areas within biochemistry, genetics, and molecular biology, with a particular focus on medical applications related to metabolism and genetic disorders. Millington has contributed to a diverse range of fields including molecular biology, clinical biochemistry, physiology, rheumatology, and cell biology.

Their work addresses several key topics such as metabolism and genetic disorders, folate and B vitamins research, lysosomal storage disorders research, proteoglycans and glycosaminoglycans research, metabolomics and mass spectrometry studies, neurogenetic and muscular disorders research, and carbohydrate chemistry and synthesis.

Millington has published extensively, with a number of recent papers that illustrate their ongoing research interests and collaborations. Notable publications include:

  • "Evaluation of X-Linked Adrenoleukodystrophy Newborn Screening in North Carolina," 2020, JAMA Network Open
  • "Successful Implementation of Expanded Newborn Screening in the Philippines Using Tandem Mass Spectrometry," 2022, International Journal of Neonatal Screening
  • "How mass spectrometry revolutionized newborn screening," 2024, Journal of Mass Spectrometry and Advances in the Clinical Lab
  • "Digital Microfluidics in Newborn Screening for Mucopolysaccharidoses: A Progress Report," 2020, International Journal of Neonatal Screening
  • "Addition of MPS-II to the Recommended Uniform Screening Panel in the United States," 2022, International Journal of Neonatal Screening

Their frequent publication venues highlight a strong presence in journals focused on neonatal screening and clinical protocols, including:

  • International Journal of Neonatal Screening
  • Current Protocols
  • JAMA Network Open
  • Journal of Mass Spectrometry and Advances in the Clinical Lab
  • Clinica Chimica Acta

Collaboration is a significant aspect of Millington's research, with recurring co-authors such as Sarah P. Young, Ashlee R. Stiles, James Beasley, Haoyue Zhang, and Iskren Menkovic. These partnerships indicate interdisciplinary and cross-institutional efforts within their field of study.

Best Publications

  • A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

    Christopher B. Newgard;Jie An;James R. Bain;Michael J. Muehlbauer

  • Pompe disease diagnosis and management guideline

    Priya S Kishnani;Robert D Steiner;Deeksha Bali;Kenneth Berger

  • Tandem mass spectrometry: A new method for acylcarnitine profiling with potential for neonatal screening for inborn errors of metabolism

    D. S. Millington;N. Kodo;D. L. Norwood;C. R. Roe

  • Rapid diagnosis of phenylketonuria by quantitative analysis for phenylalanine and tyrosine in neonatal blood spots by tandem mass spectrometry.

    D H Chace;D S Millington;N Terada;S G Kahler

  • Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance

    Jie An;Deborah M Muoio;Masakazu Shiota;Yuka Fujimoto

  • Identity and yields of major halogenated products of aquatic fulvic acid chlorination.

    R F Christman;D L Norwood;D S Millington;J D Johnson

  • Rapid diagnosis of maple syrup urine disease in blood spots from newborns by tandem mass spectrometry.

    D H Chace;S L Hillman;D S Millington;S G Kahler

  • The tandem mass spectrometry newborn screening experience in North Carolina: 1997-2005

    D. M. Frazier;D. S. Millington;S. E. McCandless;D. D. Koeberl

  • Application of fast atom bombardment with tandem mass spectrometry and liquid chromatography/ mass spectrometry to the analysis of acylcarnitines in human urine, blood, and tissue

    D.S. Millington;D.L. Norwood;N. Kodo;C.R. Roe

  • Targeted disruption of mouse long-chain acyl-CoA dehydrogenase gene reveals crucial roles for fatty acid oxidation

    D. M. Kurtz;P. Rinaldo;W. J. Rhead;Liqun Tian

  • Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency: diagnosis by acylcarnitine analysis in blood.

    J. L. K. Van Hove;Wen Zhang;S. G. Kahler;C. R. Roe

  • The structure of the molybdenum cofactor. Characterization of di-(carboxamidomethyl)molybdopterin from sulfite oxidase and xanthine oxidase.

    S P Kramer;J L Johnson;A A Ribeiro;D S Millington

  • The analysis of diagnostic markers of genetic disorders in human blood and urine using tandem mass spectrometry with liquid secondary ion mass spectrometry

    David S. Millington;Naoki Kodo;Naoto Terada;Diane Roe

  • Rapid diagnosis of homocystinuria and other hypermethioninemias from newborns' blood spots by tandem mass spectrometry.

    D H Chace;S L Hillman;D S Millington;S G Kahler

  • Acute fatty liver of pregnancy and long-chain 3-hydroxyacyl–coenzyme A dehydrogenase deficiency

    William R. Treem;Piero Rinaldo;Daniel E. Hale;Charles A. Stanley

  • Recognition of medium-chain acyl-CoA dehydrogenase deficiency in asymptomatic siblings of children dying of sudden infant death or Reye-like syndromes

    Charles R. Roe;David S. Millington;David A. Maltby;P. Kinnebrew

  • L-carnitine enhances excretion of propionyl coenzyme A as propionylcarnitine in propionic acidemia.

    Charles R. Roe;David S. Millington;David A. Maltby;Timothy P. Bohan

  • Acute fatty liver of pregnancy, hemolysis, elevated liver enzymes, and low platelets syndrome, and long chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency

    William R. Treem;Marie E. Shoup;Daniel E. Hale;Michael J. Bennett

  • Diagnostic and Therapeutic Implications of Medium-Chain Acylcarnitines in the Medium-Chain Acyl-CoA Dehydrogenase Deficiency

    Charles R Roe;David S Millington;David A Maltby;Timothy P Bohan

  • Valproylcarnitine: a novel drug metabolite identified by fast atom bombardment and thermospray liquid chromatography-mass spectrometry.

    David S. Millington;Timothy P. Bohan;Charles R. Roe;Alfred L. Yergey

Frequent Co-Authors

Yuan-Tsong Chen
Yuan-Tsong Chen Harbor–UCLA Medical Center
Priya S. Kishnani
Priya S. Kishnani Duke University
Piero Rinaldo
Piero Rinaldo Mayo Clinic
Jerry Vockley
Jerry Vockley University of Pittsburgh
Dietrich Matern
Dietrich Matern Mayo Clinic
Jer-Yuarn Wu
Jer-Yuarn Wu Academia Sinica
Michael J. Bennett
Michael J. Bennett University Hospital Southampton NHS Foundation Trust
Ivan Spasojevic
Ivan Spasojevic Duke University
Niels Gregersen
Niels Gregersen Aarhus University Hospital

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