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Christophe Biot

Christophe Biot

D-Index & Metrics

Chemistry

D-Index
58
Citations
9593
World Ranking
10844
National Ranking
401

Overview

Christophe Biot is affiliated with the University of Lille in France and has contributed extensively to the field of Biochemistry, Genetics, and Molecular Biology, with a focus on Molecular Biology, Organic Chemistry, Materials Chemistry, Plant Science, and Radiology, Nuclear Medicine and Imaging.

Their main research topics include Glycosylation and Glycoproteins Research, Click Chemistry and Applications, Plant Gene Expression Analysis, Monoclonal and Polyclonal Antibodies Research, Carbohydrate Chemistry and Synthesis, Horticultural and Viticultural Research, and Crystallization and Solubility Studies.

Recent publications by Christophe Biot include:

  • "To View Your Biomolecule, Click inside the Cell" (2021), Angewandte Chemie International Edition
  • "UDP-GLYCOSYLTRANSFERASE 72E3 Plays a Role in Lignification of Secondary Cell Walls in Arabidopsis" (2020), International Journal of Molecular Sciences
  • "REPRISAL: mapping lignification dynamics using chemistry, data segmentation, and ratiometric analysis" (2021), PLANT PHYSIOLOGY
  • "To View Your Biomolecule, Click inside the Cell" (2021), Angewandte Chemie
  • "Structure-Based Design and Synthesis of Piperidinol-Containing Molecules as New Mycobacterium abscessus Inhibitors" (2020), ChemistryOpen

Christophe Biot collaborates frequently with several researchers, among whom are:

  • Cédric Lion
  • Corentin Spriet
  • Clémence Simon
  • Godfrey Neutelings
  • Vincent Rigolot

Their work has been published in various venues multiple times, including:

  • ChemBioChem
  • Zenodo (CERN European Organization for Nuclear Research)
  • The Cambridge Structural Database
  • Scientific Reports
  • Chemical Communications

Best Publications

  • Synthesis and antimalarial activity in vitro and in vivo of a new ferrocene-chloroquine analogue.

    C Biot;G Glorian;L A Maciejewski;J S Brocard

  • Design and Synthesis of Hydroxyferroquine Derivatives with Antimalarial and Antiviral Activities

    Christophe Biot;Wassim Daher;Natascha Chavain;Thierry Fandeur

  • Ferrocene Conjugates of Chloroquine and other Antimalarials: the Development of Ferroquine, a New Antimalarial

    Daniel Dive;Christophe Biot

  • 5-substituted tetrazoles as bioisosteres of carboxylic acids. Bioisosterism and mechanistic studies on glutathione reductase inhibitors as antimalarials.

    Christophe Biot;Holger Bauer;R Heiner Schirmer;Elisabeth Davioud-Charvet

  • In Vitro Antimalarial Activity of a New Organometallic Analog, Ferrocene-Chloroquine

    Olivier Domarle;Georgette Blampain;Huguette Agnaniet;T. Nzadiyabi

  • The antimalarial ferroquine: role of the metal and intramolecular hydrogen bond in activity and resistance.

    Faustine Dubar;Timothy J Egan;Bruno Pradines;David Kuter

  • Insights into the mechanism of action of ferroquine. Relationship between physicochemical properties and antiplasmodial activity.

    Christophe Biot;Donatella Taramelli;Isabelle Forfar-Bares;Lucien A. Maciejewski

  • The antimalarial ferroquine: from bench to clinic

    Christophe Biot;F. Nosten;L. Fraisse;D. Ter-Minassian

  • Ferroquine, an Ingenious Antimalarial Drug –Thoughts on the Mechanism of Action

    Faustine Dubar;Jamal Khalife;Jacques Brocard;Daniel Dive

  • A prodrug form of a Plasmodium falciparum glutathione reductase inhibitor conjugated with a 4-anilinoquinoline

    Elisabeth Davioud-Charvet;Sandrine Delarue;Christophe Biot;Babett Schwöbel

  • Synthesis and antifungal activity of a ferrocene-fluconazole analogue.

    Christophe Biot;Nadine François;Lucien Maciejewski;Jacques Brocard

  • The therapeutic potential of metal-based antimalarial agents: Implications for the mechanism of action

    Christophe Biot;Christophe Biot;William Castro;Cyrille Y. Botté;Cyrille Y. Botté;Maribel Navarro

  • In vitro and in vivo antimalarial activity of ferrochloroquine, a ferrocenyl analogue of chloroquine against chloroquine-resistant malaria parasites.

    Laurence Delhaes;Huguette Abessolo;Christophe Biot;Laurence Berry

  • Synthesis and antimalarial activity in vitro of potential metabolites of ferrochloroquine and related compounds.

    Christophe Biot;Laurence Delhaes;Cheikh M. N'Diaye;Lucien Maciejewski

  • Synthetic ferrocenic mefloquine and quinine analoguesas potential antimalarial agents.

    Christophe Biot;Laurence Delhaes;Lucien A Maciejewski;Marlène Mortuaire

  • Investigation of the Redox Behavior of Ferroquine, a New Antimalarial

    Natascha Chavain;Hervé Vezin;Daniel Dive;Nadia Touati

  • Bioorganometallic Compounds with Antimalarial Targets: Inhibiting Hemozoin Formation

    Maribel Navarro;William Castro;Christophe Biot

  • Histidine-Aromatic Interactions in Proteins and Protein-Ligand Complexes: Quantum Chemical Study of X-ray and Model Structures.

    Emilie Cauët;Marianne Rooman;René Wintjens;Jacques Liévin

  • Organometallic complexes: new tools for chemotherapy.

    N Chavain;C Biot

  • The Ferroquine Antimalarial Conundrum: Redox Activation and Reinvasion Inhibition

    Faustine Dubar;Christian Slomianny;Jamal Khalife;Daniel Dive

  • Synthesis of ferroquine enantiomers: first investigation of effects of metallocenic chirality upon antimalarial activity and cytotoxicity.

    Laurence Delhaes;Christophe Biot;Laurence Berry;Philippe Delcourt

Frequent Co-Authors

Yann Guérardel
Yann Guérardel University of Lille
Laurent Kremer
Laurent Kremer Institut de Recherche en Infectiologie de Montpellier
Bruno Pradines
Bruno Pradines Aix-Marseille University
Daniel Camus
Daniel Camus Institut Pasteur
Christian Slomianny
Christian Slomianny University of Lille
Kelly Chibale
Kelly Chibale University of Cape Town
Hervé Vezin
Hervé Vezin University of Lille
Czeslaw Wychowski
Czeslaw Wychowski University of Lille
Jean-Louis Herrmann
Jean-Louis Herrmann Versailles Saint-Quentin-en-Yvelines University
Peter Cloetens
Peter Cloetens European Synchrotron Radiation Facility

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