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Yann Guérardel

Yann Guérardel

D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
8419
World Ranking
18045
National Ranking
811

Overview

Yann Guérardel is affiliated with the University of Lille in France and has contributed extensively to the fields of biochemistry, genetics, and molecular biology, with a research portfolio also covering medicine. Their work includes a substantial focus on molecular biology, infectious diseases, immunology, ecology, and epidemiology.

Their research interests and publications prominently feature several specific topics:

  • Glycosylation and Glycoproteins Research
  • Genomics and Phylogenetic Studies
  • Bacteriophages and microbial interactions
  • Mycobacterium research and diagnosis
  • Probiotics and Fermented Foods
  • Tuberculosis Research and Epidemiology
  • Bacterial Genetics and Biotechnology

Guérardel has published in various scientific venues with frequent contributions to bioRxiv (Cold Spring Harbor Laboratory), the Journal of Biological Chemistry, Carbohydrate Polymers, mBio, and the International Journal of Molecular Sciences.

Their recent papers include:

  • Complete Structure of the Enterococcal Polysaccharide Antigen (EPA) of Vancomycin-Resistant Enterococcus faecalis V583 Reveals that EPA Decorations Are Teichoic Acids Covalently Linked to a Rhamnopolysaccharide Backbone, 2020, mBio
  • The sps Genes Encode an Original Legionaminic Acid Pathway Required for Crust Assembly in Bacillus subtilis, 2020, mBio
  • Profiling of O-acetylated Gangliosides Expressed in Neuroectoderm Derived Cells, 2020, International Journal of Molecular Sciences
  • Glycopeptidolipid glycosylation controls surface properties and pathogenicity in Mycobacterium abscessus, 2022, Cell chemical biology
  • The endogenous galactofuranosidase GlfH1 hydrolyzes mycobacterial arabinogalactan, 2020, Journal of Biological Chemistry

Frequent collaborators in their research include Yannick Rossez, Emmanuel Maes, Clément Delannoy, Louis-David Leclercq, and Laurent Kremer, each having coauthored multiple publications with Guérardel.

Best Publications

  • Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harbouring drug-tolerant bacteria.

    Anil K. Ojha;Anthony D. Baughn;Dhinakaran Sambandan;Tsungda Hsu

  • Toll-Like Receptor 2 (TLR2)-Dependent-Positive and TLR2-Independent-Negative Regulation of Proinflammatory Cytokines by Mycobacterial Lipomannans

    Valerie J F Vj Quesniaux;Delphine Dm Nicolle;David Torres;Laurent Kremer

  • Mycobacterium tuberculosis Lipomannan Induces Apoptosis and Interleukin-12 Production in Macrophages

    D. N. Dao;L. Kremer;Y. Guérardel;A. Molano

  • Lipomannans, but not lipoarabinomannans, purified from Mycobacterium chelonae and Mycobacterium kansasii induce TNF-alpha and IL-8 secretion by a CD14-toll-like receptor 2-dependent mechanism.

    Cécile Vignal;Yann Guérardel;Laurent Kremer;Maryse Masson

  • Structural Study of Lipomannan and Lipoarabinomannan fromMycobacterium chelonae PRESENCE OF UNUSUAL COMPONENTS WITH α1,3-MANNOPYRANOSE SIDE CHAINS

    Yann Guérardel;Emmanuel Maes;Elisabeth Elass;Yves Leroy

  • Thiacetazone, an antitubercular drug that inhibits cyclopropanation of cell wall mycolic acids in mycobacteria

    Anuradha Alahari;Xavier Trivelli;Yann Guérardel;Lynn G. Dover

  • Enzymatic hydrolysis of trehalose dimycolate releases free mycolic acids during mycobacterial growth in biofilms.

    Anil K. Ojha;Xavier Trivelli;Yann Guerardel;Laurent Kremer

  • Gangliosides: Structures, Biosynthesis, Analysis, and Roles in Cancer.

    Sophie Groux-Degroote;Yann Guérardel;Philippe Delannoy

  • The nematode Caenorhabditis elegans synthesizes unusual O-linked glycans: identification of glucose-substituted mucin-type O-glycans and short chondroitin-like oligosaccharides.

    Yann Guérardel;Luis Balanzino;Emmanuel Maes;Yves Leroy

  • Modulation of intestinal inflammation by yeasts and cell wall extracts: strain dependence and unexpected anti-inflammatory role of glucan fractions.

    Samir Jawhara;Samir Jawhara;Khalid Habib;Khalid Habib;François Maggiotto;François Maggiotto;Georges Pignede

  • Mycobacterial lipomannan induces granuloma macrophage fusion via a TLR2-dependent, ADAM9- and beta1 integrin-mediated pathway.

    Marie-Pierre Puissegur;Guillaume Lay;Martine Gilleron;Laure Botella

  • Evolution of Plant-Like Crystalline Storage Polysaccharide in the Protozoan Parasite Toxoplasma gondii Argues for a Red Alga Ancestry

    Alexandra Coppin;Jean-Stéphane Varré;Luc Lienard;David Dauvillée

  • The Ferroquine Antimalarial Conundrum: Redox Activation and Reinvasion Inhibition

    Faustine Dubar;Christian Slomianny;Jamal Khalife;Daniel Dive

  • TLR2-dependent eosinophil interactions with mycobacteria : role of α-defensins

    Virginie Driss;Fanny Legrand;Emmanuel Hermann;Sylvie Loiseau

  • Differences in Lactococcal Cell Wall Polysaccharide Structure Are Major Determining Factors in Bacteriophage Sensitivity

    Stuart Ainsworth;Irina Sadovskaya;Evguenii Vinogradov;Pascal Courtin;Pascal Courtin

  • Lipomannan and Lipoarabinomannan from a Clinical Isolate of Mycobacterium kansasii NOVEL STRUCTURAL FEATURES AND APOPTOSIS-INDUCING PROPERTIES

    Yann Guérardel;Emmanuel Maes;Volker Briken;Frédéric Chirat

  • Platinum(II) and palladium(II) complexes with (N,N') and (C,N,N')- ligands derived from pyrazole as anticancer and antimalarial agents: synthesis, characterization and in vitro activities.

    Josefina Quirante;Daniel Ruiz;Asensio Gonzalez;Concepción López

  • Quantification of the extracellular matrix of the Listeria monocytogenes biofilms of different phylogenic lineages with optimization of culture conditions

    Typhaine Combrouse;Typhaine Combrouse;Typhaine Combrouse;Irina Sadovskaya;Christine Faille;Ossarath Kol

  • A new piperidinol derivative targeting mycolic acid transport in Mycobacterium abscessus.

    Christian Dupont;Christian Dupont;Albertus Viljoen;Faustine Dubar;Mickaël Blaise

  • Identification of a New Family of Genes Involved in β-1,2-Mannosylation of Glycans in Pichia pastoris and Candida albicans

    Céline Mille;Piotr Bobrowicz;Pierre-André Trinel;Huijuan Li

Frequent Co-Authors

Laurent Kremer
Laurent Kremer Institut de Recherche en Infectiologie de Montpellier
Christophe Biot
Christophe Biot University of Lille
Daniel Poulain
Daniel Poulain University of Lille
Philippe Delannoy
Philippe Delannoy University of Lille
Gérard Strecker
Gérard Strecker University of Lille
Boualem Sendid
Boualem Sendid University of Lille
Kay-Hooi Khoo
Kay-Hooi Khoo National Taiwan University
Christian Slomianny
Christian Slomianny University of Lille
Manfred Wuhrer
Manfred Wuhrer Leiden University Medical Center
Jean-Louis Herrmann
Jean-Louis Herrmann Versailles Saint-Quentin-en-Yvelines University

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