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Todd L. Lowary

Todd L. Lowary

D-Index & Metrics

Chemistry

D-Index
63
Citations
11450
World Ranking
8613
National Ranking
221

Research.com Recognitions

  • 2020 - Fellow of the Royal Society of Canada Academy of Science
  • 2011 - Fellow of the American Chemical Society
  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Todd L. Lowary is affiliated with the University of Alberta in Canada and has made numerous contributions in the fields of biochemistry, genetics, molecular biology, and medicine. Their research spans several subfields including molecular biology, organic chemistry, epidemiology, infectious diseases, and ecology.

The primary topics of their work include:

  • Glycosylation and glycoproteins research
  • Carbohydrate chemistry and synthesis
  • Bacteriophages and microbial interactions
  • Mycobacterium research and diagnosis
  • Tuberculosis research and epidemiology
  • Monoclonal and polyclonal antibodies research
  • Biochemical and molecular research

Lowary has authored papers in well-known publication venues. Their frequent venues of publication include:

  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biological Chemistry
  • Nature Chemical Biology
  • Proceedings of the National Academy of Sciences

Recent notable papers authored or co-authored by Lowary include:

  • "Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2", 2021, Nature Chemical Biology
  • "Diagnostic accuracy of 3 urine lipoarabinomannan tuberculosis assays in HIV-negative outpatients", 2020, Journal of Clinical Investigation
  • "Genetically encoded multivalent liquid glycan array displayed on M13 bacteriophage", 2021, Nature Chemical Biology
  • "Capsular glycan recognition provides antibody-mediated immunity against tuberculosis", 2020, Journal of Clinical Investigation
  • "Cryo-EM Structures and Regulation of Arabinofuranosyltransferase AftD from Mycobacteria", 2020, Molecular Cell

Frequent co-authors collaborating with Lowary include:

  • Chris Whitfield
  • Lori J. West
  • Matthew S. Macauley
  • Mirat Sojitra
  • Ratmir Derda

Throughout their career, Lowary has been recognized by several prestigious organizations. Awards include:

  • Fellow of the Royal Society of Canada, 2020, Academy of Science
  • Fellow of the American Chemical Society, 2011
  • Fellow of the American Association for the Advancement of Science (AAAS), 2010

Best Publications

  • Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2.

    Linh Nguyen;Kelli A McCord;Duong T Bui;Kim M Bouwman

  • Chemistry and biology of galactofuranose-containing polysaccharides.

    Michele R. Richards;Todd L. Lowary

  • Novel lipoarabinomannan point-of-care tuberculosis test for people with HIV: a diagnostic accuracy study.

    Tobias Broger;Bianca Sossen;Elloise du Toit;Elloise du Toit;Andrew D Kerkhoff

  • Selective detection and site-analysis of O-GlcNAc-modified glycopeptides by beta-elimination and tandem electrospray mass spectrometry.

    Kenneth D. Greis;Bradley K. Hayes;Frank I. Comer;Marion Kirk

  • DC-SIGN(+) Macrophages Control the Induction of Transplantation Tolerance.

    Patricia Conde;Mercedes Rodriguez;William van der Touw;Ana Jimenez

  • Computational analysis of the potential energy surfaces of glycerol in the gas and aqueous phases: effects of level of theory, basis set, and solvation on strongly intramolecularly hydrogen-bonded systems.

    Christopher S. Callam;Sherwin J. Singer;Todd L. Lowary;Christopher M. Hadad

  • Recent advances in the synthesis of 2-deoxy-glycosides.

    Dianjie Hou;Todd L. Lowary

  • Synthesis of the docosanasaccharide arabinan domain of mycobacterial arabinogalactan and a proposed octadecasaccharide biosynthetic precursor.

    Maju Joe;Yu Bai;Ruel C Nacario;Todd L Lowary

  • The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium–host interaction

    B. J. Appelmelk;J. Den Dunnen;N. N. Driessen;R. Ummels

  • Conformational analysis of furanoside-containing mono- and oligosaccharides.

    Hashem A. Taha;Michele R. Richards;Todd L. Lowary

  • Association of Human Antibodies to Arabinomannan With Enhanced Mycobacterial Opsonophagocytosis and Intracellular Growth Reduction.

    Tingting Chen;Caroline Blanc;Anke Z. Eder;Rafael Prados-Rosales

  • Expression, purification, and characterization of a galactofuranosyltransferase involved in Mycobacterium tuberculosis arabinogalactan biosynthesis.

    Natisha L Rose;Gladys C Completo;Shuang-Jun Lin;Michael McNeil

  • Galactosyl Transferases in Mycobacterial Cell Wall Synthesis

    Martina Belánová;Petronela Dianisková;Patrick J Brennan;Gladys C Completo

  • 2,3-Anhydro sugars in glycoside bond synthesis. Highly stereoselective syntheses of oligosaccharides containing α-and β-arabinofuranosyl linkages

    Rajendrakumar Reddy Gadikota;Christopher S Callam;Timothy Wagner;Brian Del Fraino

  • Recognition of synthetic O-methyl, epimeric, and amino analogues of the acceptor α-L-Fucp-(1 → 2)-β-D-Galp-OR glycosyltransferases☆☆☆

    Todd L. Lowary;Ole Hindsgaul

  • Biosynthesis of mycobacterial arabinogalactan : identification of a novel α(1→3) arabinofuranosyltransferase

    Helen L. Birch;Luke J. Alderwick;Apoorva Bhatt;Doris Rittmann

  • Oligosaccharide Mimetics Obtained by Novel, Rapid Screening of Carboxylic Acid Encoded Glycopeptide Libraries

    Phaedria M. St. Hilaire;Todd L. Lowary;and Morten Meldal;Klaus Bock

  • Identification of the mycobacterial carbohydrate structure that binds the C-type lectins DC-SIGN, L-SIGN and SIGNR1.

    Estella A Koppel;Irene S Ludwig;Marta Sanchez Hernandez;Todd L Lowary

  • A Novel Sensitive Immunoassay Targeting the 5-Methylthio-d-Xylofuranose-Lipoarabinomannan Epitope Meets the WHO's Performance Target for Tuberculosis Diagnosis.

    George B. Sigal;Abraham Pinter;Todd L. Lowary;Masanori Kawasaki

  • Conserved glycolipid termini in capsular polysaccharides synthesized by ATP-binding cassette transporter-dependent pathways in Gram-negative pathogens

    Lisa M. Willis;Jacek Stupak;Michele R. Richards;Todd L. Lowary

  • Basis for selection of improved carbohydrate-binding single-chain antibodies from synthetic gene libraries

    Su-Jun Deng;C. R. Mackenzie;T. Hirama;R. Brousseau

  • Sequence Analysis of the GntII (Subsidiary) System for Gluconate Metabolism Reveals a Novel Pathway for l-Idonic Acid Catabolism in Escherichia coli

    Christoph Bausch;Norbert Peekhaus;Cristina Utz;Tessa Blais

Frequent Co-Authors

Jillian M. Buriak
Jillian M. Buriak University of Alberta
Christopher M. Hadad
Christopher M. Hadad The Ohio State University
Gurdyal S. Besra
Gurdyal S. Besra University of Birmingham
Chris Whitfield
Chris Whitfield University of Guelph
John S. Klassen
John S. Klassen University of Alberta
Francis D'Souza
Francis D'Souza University of North Texas
Michael R. McNeil
Michael R. McNeil Colorado State University
Michael J. Ferguson
Michael J. Ferguson University of Alberta
Ole Hindsgaul
Ole Hindsgaul University of Alberta
Abraham Pinter
Abraham Pinter Rutgers, The State University of New Jersey

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