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John S. Klassen

John S. Klassen

D-Index & Metrics

Chemistry

D-Index
53
Citations
8042
World Ranking
13271
National Ranking
361

Overview

John S. Klassen is affiliated with the University of Alberta in Canada. Their research mainly spans the fields of Biochemistry, Genetics and Molecular Biology, with a significant focus on Molecular Biology and Medicine.

Klassen's recent publications cover a range of topics related to glycobiology, viral entry mechanisms, and protein interactions. Selected recent papers include:

  • Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2, 2021, Nature Chemical Biology
  • A versatile soluble siglec scaffold for sensitive and quantitative detection of glycan ligands, 2020, Nature Communications
  • Carbohydrate Sulfation As a Mechanism for Fine-Tuning Siglec Ligands, 2021, ACS Chemical Biology
  • Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation, 2020, Nature Communications
  • Submicron Emitters Enable Reliable Quantification of Weak Protein-Glycan Interactions by ESI-MS, 2021, Analytical Chemistry

Their research topics reflect a strong emphasis on:

  • Glycosylation and Glycoproteins Research
  • Carbohydrate Chemistry and Synthesis
  • SARS-CoV-2 and COVID-19 Research
  • Monoclonal and Polyclonal Antibodies Research
  • Mass Spectrometry Techniques and Applications
  • Bacterial biofilms and quorum sensing
  • Enzyme Structure and Function

Klassen frequently collaborates with several other researchers, among them:

  • Elena N. Kitova (33 publications)
  • Duong T. Bui (22 publications)
  • Matthew S. Macauley (19 publications)
  • Lara K. Mahal (17 publications)
  • Ling Han (15 publications)

Publication venues where Klassen's work predominantly appears include:

  • Analytical Chemistry (10 publications)
  • Nature Communications (7 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (7 publications)
  • ACS Chemical Biology (3 publications)
  • Journal of the American Chemical Society (3 publications)

The scientist's subfields of study are diverse and include:

  • Molecular Biology
  • Infectious Diseases
  • Organic Chemistry
  • Spectroscopy
  • Radiology, Nuclear Medicine and Imaging

Best Publications

  • Reliable Determinations of Protein–Ligand Interactions by Direct ESI-MS Measurements. Are We There Yet?

    Elena N. Kitova;Amr El-Hawiet;Paul D. Schnier;John S. Klassen

  • Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2.

    Linh Nguyen;Kelli A McCord;Duong T Bui;Kim M Bouwman

  • Method for distinguishing specific from nonspecific protein-ligand complexes in nanoelectrospray ionization mass spectrometry.

    Jiangxiao Sun;Elena N Kitova;Weijie Wang;John S Klassen

  • Influence of Solution and Gas Phase Processes on Protein−Carbohydrate Binding Affinities Determined by Nanoelectrospray Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

    Weijie Wang;Elena N. Kitova;John S. Klassen

  • The Peptidisc, a simple method for stabilizing membrane proteins in detergent-free solution.

    Michael Luke Carlson;John William Young;Zhiyu Zhao;Lucien Fabre

  • Thermal decomposition of a gaseous multiprotein complex studied by blackbody infrared radiative dissociation. Investigating the origin of the asymmetric dissociation behavior.

    Natalia Felitsyn;Elena N. Kitova;John S. Klassen

  • Activation energies for dissociation of double strand oligonucleotide anions: evidence for watson-crick base pairing in vacuo.

    Paul D. Schnier;John S. Klassen;Eric F. Strittmatter;Evan R. Williams

  • Optogenetic control with a photocleavable protein, PhoCl

    Wei Zhang;Alexander W Lohman;Yevgeniya Zhuravlova;Xiaocen Lu

  • Functional Characterization of Bacterial Oligosaccharyltransferases Involved in O-Linked Protein Glycosylation

    Amirreza Faridmoayer;Messele A. Fentabil;Dominic C. Mills;John S. Klassen

  • Reaction Enthalpies for M+L = M+ + L, Where M+ = Na+ and K+ and L = Acetamide, N-Methylacetamide, N,N-Dimethylacetamide, Glycine, and Glycylglycine, from Determinations of the Collision-Induced Dissociation Thresholds

    John S. Klassen;Stephen G. Anderson;and Arthur T. Blades;Paul Kebarle

  • Collision-Induced Dissociation Threshold Energies of Protonated Glycine, Glycinamide, and Some Related Small Peptides and Peptide Amino Amides

    John S. Klassen;Paul Kebarle

  • Method for stabilizing protein-ligand complexes in nanoelectrospray ionization mass spectrometry.

    Jiangxiao Sun;Elena N. Kitova;John S. Klassen

  • Hydrophobic protein-ligand interactions preserved in the gas phase.

    Lan Liu;Dhanashri Bagal;Elena N. Kitova;Paul D. Schnier

  • DETERMINATIONS OF ION-MOLECULE EQUILIBRIA INVOLVING IONS PRODUCED BY ELECTROSPRAY. HYDRATION OF PROTONATED AMINES, DIAMINES, AND SOME SMALL PEPTIDES

    John S. Klassen;Arthur T. Blades;Paul Kebarle

  • Hydration of Gas-Phase Gramicidin S (M + 2H)2+ Ions Formed by Electrospray: The Transition From Solution to Gas-Phase Structure

    Sandra E. Rodriguez-Cruz;John S. Klassen;Evan R. Williams

  • Nonspecific protein-carbohydrate complexes produced by nanoelectrospray ionization. Factors influencing their formation and stability.

    Weijie Wang;Elena N. Kitova;John S. Klassen

  • Droplet Electrospray Mass Spectrometry

    Darcy B. Hager;Norman J. Dovichi;John. Klassen;Paul. Kebarle

  • Ligand specificity of CS-35, a monoclonal antibody that recognizes mycobacterial lipoarabinomannan: a model system for oligofuranoside-protein recognition.

    Christoph Rademacher;Glen K. Shoemaker;Hyo-Sun Kim;Ruixiang Blake Zheng

  • FREE ENERGIES OF HYDRATION IN THE GAS PHASE OF THE ANIONS OF SOME OXO ACIDS OF C, N, S, P, CL, AND I

    Arthur T. Blades;John S. Klassen;Paul Kebarle

  • Determination of protein-ligand association thermochemistry using variable-temperature nanoelectrospray mass spectrometry.

    Rambod Daneshfar;Elena N Kitova;John S Klassen

  • Trapping and characterization of covalent intermediates of mutant retaining glycosyltransferases

    Naoto Soya;Ying Fang;Monica M Palcic;John S Klassen

Frequent Co-Authors

Xi Jiang
Xi Jiang Cincinnati Children's Hospital Medical Center
Ming Tan
Ming Tan Cincinnati Children's Hospital Medical Center
Todd L. Lowary
Todd L. Lowary University of Alberta
Gilbert G. Privé
Gilbert G. Privé University of Toronto
David R. Bundle
David R. Bundle University of Alberta
Paul Kebarle
Paul Kebarle University of Alberta
Evan R. Williams
Evan R. Williams University of California, Berkeley
Monica M. Palcic
Monica M. Palcic Carlsberg Laboratory
P. Lynne Howell
P. Lynne Howell University of Toronto
Jeroen D. C. Codée
Jeroen D. C. Codée Leiden University

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