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David R. Bundle

David R. Bundle

D-Index & Metrics

Chemistry

D-Index
72
Citations
16115
World Ranking
5353
National Ranking
132

Biology and Biochemistry

D-Index
73
Citations
16394
World Ranking
6034
National Ranking
213

Research.com Recognitions

  • 1995 - Fellow of the Royal Society of Canada Academy of Science

Overview

David R. Bundle is a researcher affiliated with the University of Alberta in Canada, specializing in immunology and microbiology. Their research focuses extensively on areas such as immune cell function and interaction, immune response and inflammation, as well as the diagnosis, epidemiology, and treatment of Brucella infections. They have also contributed to studies on Escherichia coli and influenza virus, as well as bacteriophages and microbial interactions, and monoclonal and polyclonal antibodies.

The scientist has authored several papers, with recent publications including: The lipid globotriaosylceramide promotes germinal center B cell responses and antiviral immunity (2024) published in Science; The Tip of Brucella O-Polysaccharide Is a Potent Epitope in Response to Brucellosis Infection and Enables Short Synthetic Antigens to Be Superior Diagnostic Reagents (2022) in Microorganisms; Towards Understanding the Basis of Brucella Antigen-Antibody Specificity (2025) in Molecules; and The lipid Gb3 promotes germinal center B cell responses and anti-viral immunity (2023) available on bioRxiv (Cold Spring Harbor Laboratory).

The research venues where David R. Bundle has frequently published include Science, Microorganisms, Molecules, and bioRxiv (Cold Spring Harbor Laboratory).

Coauthorships have played a role in their research output, with frequent collaborators including Xiaolong Zhang, Kévin Ly, Yuxiang Zhang, Yu Hu, and Adam Yongxin Ye, each contributing to multiple joint publications.

The scientist's work is multidisciplinary within life sciences, covering subfields such as immunology, small animals, endocrinology, epidemiology, and ecology. Their studies incorporate a variety of biological topics that interface with immune mechanisms and infectious diseases.

David R. Bundle was recognized as a Fellow of the Royal Society of Canada in 1995, under the Academy of Science, marking a professional distinction in their scientific career.

  • Immune Cell Function and Interaction
  • Immune Response and Inflammation
  • Brucella: diagnosis, epidemiology, treatment
  • Escherichia coli research studies
  • Influenza Virus Research Studies
  • Bacteriophages and microbial interactions
  • Monoclonal and Polyclonal Antibodies Research

  • The lipid globotriaosylceramide promotes germinal center B cell responses and antiviral immunity (2024, Science)
  • The Tip of Brucella O-Polysaccharide Is a Potent Epitope in Response to Brucellosis Infection and Enables Short Synthetic Antigens to Be Superior Diagnostic Reagents (2022, Microorganisms)
  • Towards Understanding the Basis of Brucella Antigen-Antibody Specificity (2025, Molecules)
  • The lipid Gb3 promotes germinal center B cell responses and anti-viral immunity (2023, bioRxiv [Cold Spring Harbor Laboratory])

  • Xiaolong Zhang
  • Kévin Ly
  • Yuxiang Zhang
  • Yu Hu
  • Adam Yongxin Ye

  • Science
  • Microorganisms
  • Molecules
  • bioRxiv (Cold Spring Harbor Laboratory)

  • Immunology
  • Small Animals
  • Endocrinology
  • Epidemiology
  • Ecology

Best Publications

  • Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands

    Pavel I. Kitov;Joanna M. Sadowska;George Mulvey;Glen D. Armstrong

  • On the Nature of the Multivalency Effect: A Thermodynamic Model

    Pavel I Kitov;David R Bundle

  • Properties of a synthetic antigen related to the human blood-group Lewis a

    R. U. Lemieux;D. R. Bundle;D. A. Baker

  • Recognition of a cell-surface oligosaccharide of pathogenic Salmonella by an antibody Fab fragment.

    Miroslaw Cygler;David R. Rose;David R. Bundle

  • Synthetic glycopeptide vaccines combining β-mannan and peptide epitopes induce protection against candidiasis

    Hong Xin;Sebastian Dziadek;David R. Bundle;Jim E. Cutler

  • Structure of the O‐chain of the phenol‐phase soluble cellular lipopolysaccharide of Yersinia enterocolitica serotype O:9

    Martine Caroff;David R. Bundle;Malcolm B. Perry

  • Antigenic S-type lipopolysaccharide of Brucella abortus 1119-3.

    M Caroff;D R Bundle;M B Perry;J W Cherwonogrodzky

  • Linear PADRE T Helper Epitope and Carbohydrate B Cell Epitope Conjugates Induce Specific High Titer IgG Antibody Responses

    J Alexander;M F del Guercio;A Maewal;L Qiao

  • Acid-catalysed benzylation and allylation by alkyl trichloroacetimidates

    Hans-Peter Wessel;Tommy Iversen;David R. Bundle

  • Benzyl trichloroacetimidate, a versatile reagent for acid-catalysed benzylation of hydroxy-groups

    Tommy Iversen;David R. Bundle

  • Structure of a single-chain antibody variable domain (Fv) fragment complexed with a carbohydrate antigen at 1.7-A resolution.

    A. Zdanov;Y. Li;D. R. Bundle;Su-Jun Deng

  • Determination of the Structure and Conformation of Bacterial Polysaccharides by Carbon 13 Nuclear Magnetic Resonance STUDIES ON THE GROUP-SPECIFIC ANTIGENS OF NEISSERIA MENINGITIDIS SEROGROUPS A AND X

    David R. Bundle;Ian C.P. Smith;Harold J. Jennings

  • Analysis by Surface Plasmon Resonance of the Influence of Valence on the Ligand Binding Affinity and Kinetics of an Anti-carbohydrate Antibody

    C. Roger MacKenzie;Tomoko Hirama;Su-jun Deng;David R. Bundle

  • Selection of antibody single-chain variable fragments with improved carbohydrate binding by phage display.

    Su-Jun Deng;C. R. Mackenzie;J. Sadowska;J. Michniewicz

  • Assessment in Mice of the Therapeutic Potential of Tailored, Multivalent Shiga Toxin Carbohydrate Ligands

    George L Mulvey;Paola Marcato;Pavel I Kitov;Joanna Sadowska

  • THE CARBON-13 NUCLEAR MAGNETIC RESONANCE SPECTRA OF 2-ACETAMIDO-2-DEOXY-D-HEXOSES AND SOME SPECIFICALLY DEUTERIATED, O-ACETYLATED, AND PHOSPHORYLATED DERIVATIVES

    D. R. Bundle;H. J. Jennings;Ian C. P. Smith

  • Micro-Scale Frontal Affinity Chromatography with Mass Spectrometric Detection: A New Method for the Screening of Compound Libraries.

    David C. Schriemer;David R. Bundle;Liang Li;Ole Hindsgaul

  • The in situ activation of thioglycosides with bromine: an improved glycosylation method

    Jan O. Kihlberg;David A. Leigh;David R. Bundle

  • 1,2-Orthoacetate intermediates in silver trifluoromethanesulphonate promoted Koenigs–Knorr synthesis of disaccharide glycosides

    Joseph Banoub;David R. Bundle

  • Evidence for the extended helical nature of polysaccharide epitopes. The 2.8 A resolution structure and thermodynamics of ligand binding of an antigen binding fragment specific for alpha-(2-->8)-polysialic acid.

    S.V Evans;B.W Sigurskjold;H.J Jennings;J.R Brisson

Frequent Co-Authors

Malcolm B. Perry
Malcolm B. Perry National Research Council Canada
Ole Hindsgaul
Ole Hindsgaul University of Alberta
John S. Klassen
John S. Klassen University of Alberta
N. Martin Young
N. Martin Young National Research Council Canada
Jean-Robert Brisson
Jean-Robert Brisson National Research Council Canada
Monica M. Palcic
Monica M. Palcic Carlsberg Laboratory
Todd L. Lowary
Todd L. Lowary University of Alberta
Peter J. Meikle
Peter J. Meikle Baker IDI Heart and Diabetes Institute
Alf A. Lindberg
Alf A. Lindberg Karolinska Institute
Jim E. Cutler
Jim E. Cutler Louisiana State University

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