K. Lenhard Rudolph

Overview

Best Publications

• Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis

  Hashem B. El–Serag;K. Lenhard Rudolph

  6541
  Citations

• Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis

  Stefanie U. Wiemann;Ande Satyanarayana;Martina Tsahuridu;Hans L. Tillmann

  641
  Citations

• Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation

  Aaheli Roy Choudhury;Zhenyu Ju;Meta W. Djojosubroto;Andrea Schienke

  509
  Citations

• DNA damage checkpoints in stem cells, ageing and cancer

  Tobias Sperka;Jianwei Wang;Jianwei Wang;K. Lenhard Rudolph;K. Lenhard Rudolph

  498
  Citations

• Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment

  Zhenyu Ju;Hong Jiang;Maike Jaworski;Chozhavendan Rathinam

  393
  Citations

• A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage.

  Jianwei Wang;Qian Sun;Yohei Morita;Hong Jiang

  392
  Citations

• Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation.

  Kwok Kin Wong;Sandy Chang;Sarah R. Weiler;Shridar Ganesan

  381
  Citations

• Loss of p53 in Enterocytes Generates an Inflammatory Microenvironment Enabling Invasion and Lymph Node Metastasis of Carcinogen-Induced Colorectal Tumors

  Sarah Schwitalla;Paul K. Ziegler;David Horst;Valentin Becker

  285
  Citations

• Telomere length is reset during early mammalian embryogenesis.

  Sonja Schaetzlein;Andrea Lucas-Hahn;Erika Lemme;Wilfried A. Kues

  269
  Citations

• Effect of cytotoxic chemotherapy on markers of molecular age in patients with breast cancer.

  Hanna K. Sanoff;Allison M. Deal;Janakiraman Krishnamurthy;Chad Torrice

  268
  Citations

• Impaired Endothelial Repair Capacity of Early Endothelial Progenitor Cells in Prehypertension. Relation to Endothelial Dysfunction

  Giovanna Giannotti;Carola Doerries;Carola Doerries;Pavani S. Mocharla;Maja F. Mueller;Maja F. Mueller

  257
  Citations

• Cellular and epigenetic drivers of stem cell ageing.

  Maria Ermolaeva;Francesco Neri;Alessandro Ori;K Lenhard Rudolph

  229
  Citations

• Impact of genomic damage and ageing on stem cell function

  Axel Behrens;Jan M. van Deursen;K. Lenhard Rudolph;Bjoern Schumacher

  226
  Citations

• Telomere dysfunction triggers developmentally regulated germ cell apoptosis.

  Michael T. Hemann;Karl Lenhard Rudolph;Margaret A. Strong;Ronald A. DePinho

  222
  Citations

• The role of telomeres in stem cells and cancer.

  Cagatay Günes;K. Lenhard Rudolph

  212
  Citations

• Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease

  Hong Jiang;Eric Schiffer;Zhangfa Song;Jianwei Wang

  205
  Citations

• Telomerase antagonists GRN163 and GRN163L inhibit tumor growth and increase chemosensitivity of human hepatoma

  Meta W. Djojosubroto;Allison C. Chin;Ning Go;Sonja Schaetzlein

  200
  Citations

• Telomerase gene mutations are associated with cirrhosis formation.

  Daniel Hartmann;Daniel Hartmann;Ujala Srivastava;Michaela Thaler;Karin N. Kleinhans

  195
  Citations

• Telomeres and telomerase: a dual role in hepatocarcinogenesis.

  Ande Satyanarayana;Michael P. Manns;K. Lenhard Rudolph

  194
  Citations

• Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis

  Satyanarayana Ande;Stefanie Wiemann;Martina Tsahuridu;Hans Tillmann

  0
  Citations