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Gilbert G. Privé

Gilbert G. Privé

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
14795
World Ranking
13021
National Ranking
443

Overview

Gilbert G. Privé is affiliated with the University of Toronto in Canada. Their research spans multiple fields, including Biochemistry, Genetics and Molecular Biology, and Medicine. Within these broad areas, their work has a focus on subfields such as Molecular Biology, Oncology, Materials Chemistry, Immunology, and Pathology and Forensic Medicine.

The scientist's research topics cover areas like Ubiquitin and proteasome pathways, Protein Degradation and Inhibitors, Glycosylation and Glycoproteins Research, CAR-T cell therapy research, Lymphoma Diagnosis and Treatment, Perovskite Materials and Applications, and Immune Cell Function and Interaction.

Gilbert G. Privé has contributed to various scientific publications, including recent papers:

  • Machine-Learning-Accelerated Perovskite Crystallization (2020) published in Matter
  • TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate (2020) published in Cell
  • Fungal-Selective Resorcylate Aminopyrazole Hsp90 Inhibitors: Optimization of Whole-Cell Anticryptococcal Activity and Insights into the Structural Origins of Cryptococcal Selectivity (2021) published in Journal of Medicinal Chemistry
  • Structure-guided approaches to targeting stress responses in human fungal pathogens (2020) published in Journal of Biological Chemistry
  • Combined EZH2 Inhibition and IKAROS Degradation Leads to Enhanced Antitumor Activity in Diffuse Large B-cell Lymphoma (2021) published in Clinical Cancer Research

The scientist frequently publishes in venues such as Clinical Lymphoma Myeloma & Leukemia, Nature Communications, Proceedings of the National Academy of Sciences, Zenodo (CERN European Organization for Nuclear Research), and Matter.

Collaborations have formed a significant part of their work. Frequent co-authors include:

  • D.A. Kuntz
  • Darren Yong
  • Neil C. Pomroy
  • Brian Raught
  • Ahmed Mamai

Best Publications

  • Sequence and structural analysis of BTB domain proteins

    Peter J Stogios;Gregory S Downs;Jimmy J S Jauhal;Sukhjeen K Nandra

  • A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter.

    Yongjian Liu;Doris Peter;Ali Roghani;Shimon Schuldiner

  • Detergents for the stabilization and crystallization of membrane proteins.

    Gilbert G. Privé

  • The integrated landscape of driver genomic alterations in glioblastoma

    Veronique Frattini;Vladimir Trifonov;Joseph Minhow Chan;Angelica Castano

  • The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila

    Susan Zollman;Dorothea Godt;Gilbert G. Prive;Jean-Louis Couderc

  • Helix geometry, hydration, and G.A mismatch in a B-DNA decamer.

    Gilbert G. Privé;Udo Heinemann;Srinivasan Chandrasegaran;Lou Sing Kan

  • Three-dimensional structures of the ligand-binding domain of the bacterial aspartate receptor with and without a ligand.

    Michael V. Milburn;Gilbert G. Prive;Daniel L. Milligan;William G. Scott

  • Nramp defines a family of membrane proteins.

    M Cellier;G Privé;A Belouchi;T Kwan

  • Solution Structure and Dynamics of the Outer Membrane Enzyme PagP by NMR

    Peter M. Hwang;Wing-Yiu Choy;Eileen I. Lo;Lu Chen

  • Crystal structure of the BTB domain from PLZF

    Ahmad Kf;Engel Ck;Privé Gg

  • Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells.

    Jose M Polo;Tania Dell'Oso;Stella Maris Ranuncolo;Leandro Cerchietti

  • STRUCTURE OF THE B-DNA DECAMER C-C-A-A-C-G-T-T-G-G AND COMPARISON WITH ISOMORPHOUS DECAMERS C-C-A-A-G-A-T-T-G-G AND C-C-A-G-G-C-C-T-G-G

    Gilbert G. Privé;Kazunori Yanagi;Richard E. Dickerson

  • Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain.

    K.Farid Ahmad;K.Farid Ahmad;Ari Melnick;Stuart Lax;Denis Bouchard

  • A small-molecule inhibitor of BCL6 kills DLBCL cells in vitro and in vivo.

    Leandro C. Cerchietti;Alexandru F. Ghetu;Xiao-Han Zhu;Gustavo F. Da Silva

  • Analysis of local helix geometry in three B-DNA decamers and eight dodecamers.

    Kazunori Yanagi;Gilbert G. Privé;Richard E. Dickerson

  • Structure of an alternating-B DNA helix and its relationship to A-tract DNA

    Chun Yoon;Gilbert G. Prive;David S. Goodsell;Richard E. Dickerson

  • Critical residues within the BTB domain of PLZF and Bcl-6 modulate interaction with corepressors

    Ari Melnick;Graeme Carlile;K. Farid Ahmad;Chih Li Kiang

  • Crystal structure of saposin B reveals a dimeric shell for lipid binding

    Victoria E. Ahn;Kym F. Faull;Julian P. Whitelegge;Arvan L. Fluharty

  • Ubiquitylome analysis identifies dysregulation of effector substrates in SPOP-mutant prostate cancer

    Jean Philippe P Theurillat;Jean Philippe P Theurillat;Namrata D. Udeshi;Wesley J. Errington;Wesley J. Errington;Tanya Svinkina

  • In-Depth Mutational Analysis of the Promyelocytic Leukemia Zinc Finger BTB/POZ Domain Reveals Motifs and Residues Required for Biological and Transcriptional Functions

    Ari Melnick;K. Farid Ahmad;K. Farid Ahmad;Sally Arai;Adam Polinger

Frequent Co-Authors

Ari Melnick
Ari Melnick Cornell University
H. Ronald Kaback
H. Ronald Kaback University of California, Los Angeles
Richard E. Dickerson
Richard E. Dickerson University of California, Los Angeles
Régis Pomès
Régis Pomès University of Toronto
Jonathan D. Licht
Jonathan D. Licht University of Florida
Sung-Hou Kim
Sung-Hou Kim University of California, Berkeley
Kirsten Jung
Kirsten Jung Ludwig-Maximilians-Universität München
Jose M. Polo
Jose M. Polo Monash University
Kym F. Faull
Kym F. Faull University of California, Los Angeles
Julian P. Whitelegge
Julian P. Whitelegge University of California, Los Angeles

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