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Biology and Biochemistry

D-Index
87
Citations
27668
World Ranking
2827
National Ranking
1453

Overview

Kym F. Faull is affiliated with the University of California, Los Angeles in the United States. Their research spans multiple domains within medicine and biochemistry, genetics, and molecular biology.

Their recent scholarly work includes publications in notable journals such as:

  • Gut microbiota Turicibacter strains differentially modify bile acids and host lipids, 2023, Nature Communications
  • Skeletal muscle regeneration via the chemical induction and expansion of myogenic stem cells in situ or in vitro, 2021, Nature Biomedical Engineering
  • A randomized, phase 1, placebo-controlled trial of APG-157 in oral cancer demonstrates systemic absorption and an inhibitory effect on cytokines and tumor-associated microbes, 2020, Cancer
  • Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair, 2021, Journal of Clinical Investigation
  • Small molecules disaggregate alpha-synuclein and prevent seeding from patient brain-derived fibrils, 2023, Proceedings of the National Academy of Sciences

Their primary fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Subfields of particular focus are:

  • Molecular Biology
  • Physiology
  • Infectious Diseases
  • Materials Chemistry
  • Neurology

Topics covered extensively in their works are:

  • Gut microbiota and health
  • Air Quality and Health Impacts
  • Clostridium difficile and Clostridium perfringens research
  • Curcumin's Biomedical Applications
  • RNA Research and Splicing
  • RNA modifications and cancer
  • Fatty Acid Research and Health

Frequent co-authors collaborating with Kym F. Faull include:

  • Gazmend Elezi
  • Alexander J. Yoon
  • Michael E. Jung
  • Jonathan Tsang
  • Lorenz M. Urner

They have published multiple articles in the following venues more than once:

  • Journal of Biological Chemistry
  • Analytical Chemistry
  • Zenodo (CERN European Organization for Nuclear Research)
  • The Cambridge Structural Database

Best Publications

  • Protective effect of high density lipoprotein associated paraoxonase. Inhibition of the biological activity of minimally oxidized low density lipoprotein.

    A. D. Watson;J. A. Berliner;S. Y. Hama;B. N. La Du

  • Structural Identification by Mass Spectrometry of Oxidized Phospholipids in Minimally Oxidized Low Density Lipoprotein That Induce Monocyte/Endothelial Interactions and Evidence for Their Presence in Vivo

    Andrew D. Watson;Norbert Leitinger;Mohamad Navab;Kym F. Faull

  • Curcumin Structure-Function, Bioavailability, and Efficacy in Models of Neuroinflammation and Alzheimer's Disease

    Aynun N. Begum;Mychica R. Jones;Giselle P. Lim;Takashi Morihara

  • Purification and characterization of sortase, the transpeptidase that cleaves surface proteins of Staphylococcus aureus at the LPXTG motif

    Hung Ton-That;Gwen Liu;Sarkis K. Mazmanian;Kym F. Faull

  • Structure of the cell wall anchor of surface proteins in Staphylococcus aureus.

    Olaf Schneewind;Audree Fowler;Kym F. Faull

  • The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR

    Randall M. Chin;Xudong Fu;Melody Y. Pai;Laurent Vergnes

  • Epigenomic Profiling of Young and Aged HSCs Reveals Concerted Changes during Aging that Reinforce Self-Renewal

    Deqiang Sun;Min Luo;Mira Jeong;Benjamin Rodriguez

  • Combined serum paraoxonase knockout/apolipoprotein E knockout mice exhibit increased lipoprotein oxidation and atherosclerosis.

    Diana M. Shih;Yu-Rong Xia;Xu-Ping Wang;Elizabeth Miller

  • The proteomes of human parotid and submandibular/sublingual gland salivas collected as the ductal secretions

    Paul Denny;Fred K. Hagen;Markus Hardt;Lujian Liao

  • Anchoring of surface proteins to the cell wall of Staphylococcus aureus. Sortase catalyzed in vitro transpeptidation reaction using LPXTG peptide and NH(2)-Gly(3) substrates.

    Hung Ton-That;Sarkis K. Mazmanian;Kym F. Faull;Olaf Schneewind

  • Combined Deficiency of Tet1 and Tet2 Causes Epigenetic Abnormalities but Is Compatible with Postnatal Development

    Meelad M. Dawlaty;Achim Breiling;Thuc Le;Günter Raddatz

  • Tet1 is critical for neuronal activity-regulated gene expression and memory extinction

    Andrii Rudenko;Andrii Rudenko;Andrii Rudenko;Meelad M. Dawlaty;Jinsoo Seo;Jinsoo Seo;Jinsoo Seo;Albert W. Cheng

  • Characterization of serum biomarkers for detection of early stage ovarian cancer.

    Katherine R. Kozak;Feng Su;Julian P. Whitelegge;Kym Faull

  • Loss of Tet Enzymes Compromises Proper Differentiation of Embryonic Stem Cells

    Meelad M. Dawlaty;Achim Breiling;Thuc Le;M. Inmaculada Barrasa

  • A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas.

    Alice Soragni;Deanna M. Janzen;Lisa M. Johnson;Anne G. Lindgren

  • Determinants of bioactivity of oxidized phospholipids. Specific oxidized fatty acyl groups at the sn-2 position.

    Ganesamoorthy Subbanagounder;Norbert Leitinger;Dawn C. Schwenke;Jason W. Wong

  • A novel broad-spectrum antiviral targeting entry of enveloped viruses.

    Mike C. Wolf;Alexander N. Freiberg;Tinghu Zhang;Zeynep Akyol-Ataman

  • Structural identification of a novel pro-inflammatory epoxyisoprostane phospholipid in mildly oxidized low density lipoprotein

    Andrew D. Watson;Ganesamoorthy Subbanagounder;Derek S. Welsbie;Kym F. Faull

  • Pharmacologic effects in vivo in brain by vector-mediated peptide drug delivery

    Ulrich Bickel;Takayoshi Yoshikawa;Elliot M. Landaw;Kym F. Faull

  • Epoxyisoprostane and Epoxycyclopentenone Phospholipids Regulate Monocyte Chemotactic Protein-1 and Interleukin-8 Synthesis FORMATION OF THESE OXIDIZED PHOSPHOLIPIDS IN RESPONSE TO INTERLEUKIN-1β

    Ganesamoorthy Subbanagounder;Jason W. Wong;Hans Lee;Kym F. Faull

Frequent Co-Authors

Julian P. Whitelegge
Julian P. Whitelegge University of California, Los Angeles
Jack D. Barchas
Jack D. Barchas Cornell University
John G. Csernansky
John G. Csernansky Northwestern University
Olaf Schneewind
Olaf Schneewind University of Chicago
Michael E. Jung
Michael E. Jung University of California, Los Angeles
Richard L. Stevens
Richard L. Stevens Brigham and Women's Hospital
Vincent P. Zarcone
Vincent P. Zarcone Stanford University
Jonathan B. Angel
Jonathan B. Angel University of Ottawa
Kenneth L. Davis
Kenneth L. Davis Icahn School of Medicine at Mount Sinai
Alan J. Waring
Alan J. Waring University of California, Los Angeles

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