Robert S. Mittler

Robert S. Mittler publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Robert S. Mittler sits on this spectrum.

Robert S. Mittler D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Robert S. Mittler sits on this spectrum.

Overview

Best Publications

• Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

  Ignacio Melero;Walter W. Shuford;Stephanie Ashe Newby;Alejandro Aruffo

  1137
  Citations

• 4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses.

  Walter W. Shuford;Kerry Klussman;Douglas D. Tritchler;Deryk T. Loo

  977
  Citations

• Intracellular Trafficking of CTLA-4 and Focal Localization Towards Sites of TCR Engagement

  Peter S Linsley;Jeff Bradshaw;JoAnne Greene;Robert Peach

  835
  Citations

• Cutting edge: 4-1BB is a bona fide CD8 T cell survival signal.

  Chikara Takahashi;Robert S. Mittler;Anthony T. Vella

  592
  Citations

• Eradication of established tumors in mice by a combination antibody-based therapy.

  Tomoyasu Uno;Kazuyoshi Takeda;Kazuyoshi Takeda;Yuko Kojima;Hirohisa Yoshizawa

  379
  Citations

• AMPLIFICATION OF TUMOR IMMUNITY BY GENE TRANSFER OF THE CO-STIMULATORY 4-1BB LIGAND : SYNERGY WITH THE CD28 CO-STIMULATORY PATHWAY

  Ignacio Melero;Nathan Bach;Karl Erik Hellström;Alejandro Aruffo

  362
  Citations

• Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice

  James O. McNamara;Despina Kolonias;Fernando Pastor;Robert S. Mittler

  361
  Citations

• CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB × NZW F1 mice

  Juergen Foell;Simona Strahotin;Shawn P. O’Neil;Megan M. McCausland

  278
  Citations

• Correction: Corrigendum: Long-lived antigen-induced IgM plasma cells demonstrate somatic mutations and contribute to long-term protection

  Caitlin Bohannon;Ryan Powers;Lakshmipriyadarshini Satyabhama;Ang Cui

  227
  Citations

• ZAP-70 tyrosine kinase, CD45, and T cell receptor involvement in UV- and H2O2-induced T cell signal transduction.

  Gary L. Schieven;Robert S. Mittler;Steven G. Nadler;Jean M. Kirihara

  218
  Citations

• 4-1BB costimulation is required for protective anti-viral immunity after peptide vaccination.

  Joyce T. Tan;Jason K. Whitmire;Kaja Murali-Krishna;Rafi Ahmed

  203
  Citations

• Cytokine-mediated disruption of lymphocyte trafficking, hemopoiesis, and induction of lymphopenia, anemia, and thrombocytopenia in anti-CD137-treated mice.

  Liguo Niu;Simona Strahotin;Becker Hewes;Benyue Zhang

  194
  Citations

• CD134 Plus CD137 Dual Costimulation Induces Eomesodermin in CD4 T Cells To Program Cytotoxic Th1 Differentiation

  Harry Z. Qui;Adam T. Hagymasi;Suman Bandyopadhyay;Marie-Clare St. Rose

  190
  Citations

• Cutting Edge: Deficiency in the E3 Ubiquitin Ligase Cbl-b Results in a Multifunctional Defect in T Cell TGF-β Sensitivity In Vitro and In Vivo

  Elizabeth A. Wohlfert;Leonid Gorelik;Robert Mittler;Richard A. Flavell

  181
  Citations

• 4-1BB and OX40 Dual Costimulation Synergistically Stimulate Primary Specific CD8 T Cells for Robust Effector Function

  Seung-Joo Lee;Lara Myers;Guruprasaadh Muralimohan;Jie Dai

  175
  Citations

• In Vivo Triggering Through 4-1BB Enables Th-Independent Priming of CTL in the Presence of an Intact CD28 Costimulatory Pathway

  Linda Diehl;Geertje J. D. van Mierlo;Annemieke T. den Boer;Ellen van der Voort

  158
  Citations

• 4‐1BB co‐stimulation enhances human CD8+ T cell priming by augmenting the proliferation and survival of effector CD8+ T cells

  Diego Laderach;Mojgan Movassagh;Anthony Johnson;Robert S. Mittler

  152
  Citations

• Peptide-Specific CD8 T Regulatory Cells Use IFN-γ to Elaborate TGF-β-Based Suppression

  Lara Myers;Michael Croft;Byoung S. Kwon;Robert S. Mittler

  148
  Citations

• Vaccination with dendritic cells pulsed with apoptotic tumors in combination with anti-OX40 and anti-4-1BB monoclonal antibodies induces T cell-mediated protective immunity in Her-2/neu transgenic mice.

  Camilo Cuadros;Ana Lucia Dominguez;Pier-Luigi Lollini;Michael Croft

  137
  Citations

• Immunity to Pre-1950 H1N1 Influenza Viruses Confers Cross-Protection against the Pandemic Swine-Origin 2009 A (H1N1) Influenza Virus

  Ioanna Skountzou;Dimitrios G. Koutsonanos;Jin Hyang Kim;Ryan Powers

  136
  Citations