Her main research concerns Biochemistry, COQ7, Mutant, Mitochondrion and Saccharomyces cerevisiae. Biochemistry is a component of her Biosynthesis, Escherichia coli, Inner mitochondrial membrane, Peptide sequence and Oxidative phosphorylation studies. Her Oxidative phosphorylation research focuses on Oxidative stress and how it relates to Coenzyme Q10.
In her study, which falls under the umbrella issue of Mutant, Cellular respiration, Regulation of gene expression, Metabolism, ATP synthase and Protein subunit is strongly linked to Caenorhabditis elegans. Catherine F. Clarke works mostly in the field of Mitochondrion, limiting it down to topics relating to Reactive oxygen species and, in certain cases, Cofactor. In her study, Wild type is strongly linked to Mitochondrial respiratory chain, which falls under the umbrella field of Saccharomyces cerevisiae.
Catherine F. Clarke mainly investigates Biochemistry, Saccharomyces cerevisiae, Mutant, Yeast and Biosynthesis. Catherine F. Clarke performs multidisciplinary study in the fields of Biochemistry and COQ7 via her papers. Her Saccharomyces cerevisiae research incorporates elements of Genomic library, Inner mitochondrial membrane, Proton transport, Mitochondrial respiratory chain and Open reading frame.
Her Mutant study combines topics from a wide range of disciplines, such as Caenorhabditis elegans and Escherichia coli. Her studies in Yeast integrate themes in fields like Chaperone, Kinase, Respiratory electron transport chain and Phosphorylation. The study incorporates disciplines such as Antioxidant and Function in addition to Biosynthesis.
Her primary scientific interests are in Biochemistry, Yeast, Mutant, Saccharomyces cerevisiae and Biosynthesis. Her research links Function with Biochemistry. Catherine F. Clarke interconnects Mitochondrion, Respiratory electron transport chain, Mitochondrial respiratory chain, Benzoic acid and In vivo in the investigation of issues within Yeast.
Her Mutant research is classified as research in Gene. Her biological study spans a wide range of topics, including Proton transport, Cofactor and Point mutation. The concepts of her Biosynthesis study are interwoven with issues in Deamination and Escherichia coli.
Her primary areas of investigation include Biochemistry, Saccharomyces cerevisiae, Yeast, Biosynthesis and Mutant. Her study in Protein subunit, Metabolism, Lipid peroxidation, Polyunsaturated fatty acid and Alternative splicing is carried out as part of her Biochemistry studies. Her Inner mitochondrial membrane research extends to the thematically linked field of Saccharomyces cerevisiae.
Her work investigates the relationship between Yeast and topics such as Mitochondrion that intersect with problems in Gene, ERMES and Endoplasmic reticulum. The Biosynthesis study combines topics in areas such as Immunoprecipitation, Proteomics, Cofactor, Function and Open reading frame. She applies her multidisciplinary studies on Mutant and COQ7 in her research.
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Target identification using drug affinity responsive target stability (DARTS)
Brett Lomenick;Rui Hao;Nao Jonai;Randall M. Chin.
Proceedings of the National Academy of Sciences of the United States of America (2009)
The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR
Randall M. Chin;Xudong Fu;Melody Y. Pai;Laurent Vergnes.
Nature (2014)
COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness
Saskia F. Heeringa;Gil Chernin;Moumita Chaki;Weibin Zhou.
Journal of Clinical Investigation (2011)
Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q
Pamela L. Larsen;Catherine F. Clarke.
Science (2002)
ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption
Shazia Ashraf;Heon Yung Gee;Stephanie Woerner;Stephanie Woerner;Letian X. Xie.
Journal of Clinical Investigation (2013)
Endogenous synthesis of coenzyme Q in eukaryotes
UyenPhuong C. Tran;Catherine F. Clarke.
Mitochondrion (2007)
Conditional immortalization of freshly isolated human mammary fibroblasts and endothelial cells.
Michael J. O'Hare;Jacquelyn Bond;Catherine Clarke;Yasuhiro Takeuchi.
Proceedings of the National Academy of Sciences of the United States of America (2001)
A dietary source of coenzyme Q is essential for growth of long-lived Caenorhabditis elegans clk-1 mutants.
Tanya Jonassen;Pamela L. Larsen;Pamela L. Larsen;Catherine F. Clarke.
Proceedings of the National Academy of Sciences of the United States of America (2001)
The COQ7 Gene Encodes a Protein in Saccharomyces cerevisiae Necessary for Ubiquinone Biosynthesis (
B. Noelle Marbois;Catherine F. Clarke.
Journal of Biological Chemistry (1996)
Enhanced sensitivity of ubiquinone-deficient mutants of Saccharomyces cerevisiae to products of autoxidized polyunsaturated fatty acids
Thai Q. Do;Jeffery R. Schultz;Catherine F. Clarke.
Proceedings of the National Academy of Sciences of the United States of America (1996)
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