Catherine F. Clarke

Overview

Best Publications

• Target identification using drug affinity responsive target stability (DARTS)

  Brett Lomenick;Rui Hao;Nao Jonai;Randall M. Chin

  1119
  Citations

• The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR

  Randall M. Chin;Xudong Fu;Melody Y. Pai;Laurent Vergnes

  671
  Citations

• COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness

  Saskia F. Heeringa;Gil Chernin;Moumita Chaki;Weibin Zhou

  442
  Citations

• ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption

  Shazia Ashraf;Heon Yung Gee;Stephanie Woerner;Stephanie Woerner;Letian X. Xie

  369
  Citations

• Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q

  Pamela L. Larsen;Catherine F. Clarke

  355
  Citations

• Endogenous synthesis of coenzyme Q in eukaryotes

  UyenPhuong C. Tran;Catherine F. Clarke

  341
  Citations

• Conditional immortalization of freshly isolated human mammary fibroblasts and endothelial cells.

  Michael J. O'Hare;Jacquelyn Bond;Catherine Clarke;Yasuhiro Takeuchi

  294
  Citations

• A dietary source of coenzyme Q is essential for growth of long-lived Caenorhabditis elegans clk-1 mutants.

  Tanya Jonassen;Pamela L. Larsen;Pamela L. Larsen;Catherine F. Clarke

  292
  Citations

• The COQ7 Gene Encodes a Protein in Saccharomyces cerevisiae Necessary for Ubiquinone Biosynthesis (

  B. Noelle Marbois;Catherine F. Clarke

  253
  Citations

• Enhanced sensitivity of ubiquinone-deficient mutants of Saccharomyces cerevisiae to products of autoxidized polyunsaturated fatty acids

  Thai Q. Do;Jeffery R. Schultz;Catherine F. Clarke

  224
  Citations

• A regulated response to impaired respiration slows behavioral rates and increases lifespan in Caenorhabditis elegans.

  David Cristina;Michael Cary;Adam Lunceford;Catherine Clarke

  211
  Citations

• Paraoxonase 2 deficiency alters mitochondrial function and exacerbates the development of atherosclerosis.

  Asokan Devarajan;Noam Bourquard;Susan Hama;Mohamad Navab

  204
  Citations

• A C-methyltransferase involved in both ubiquinone and menaquinone biosynthesis: isolation and identification of the Escherichia coli ubiE gene.

  P T Lee;A Y Hsu;H T Ha;C F Clarke

  186
  Citations

• Molecular cloning and sequence of a cholesterol-repressible enzyme related to prenyltransferase in the isoprene biosynthetic pathway.

  C F Clarke;R D Tanaka;K Svenson;M Wamsley

  178
  Citations

• A defect in coenzyme Q biosynthesis is responsible for the respiratory deficiency in Saccharomyces cerevisiae abc1 mutants.

  Thai Q. Do;Adam Y. Hsu;Tanya Jonassen;Peter T. Lee

  176
  Citations

• Yeast clk-1 homologue (Coq7/Cat5) is a mitochondrial protein in coenzyme Q synthesis

  Tanya Jonassen;Markus Proft;Francisca Randez-Gil;Jeffery R. Schultz

  172
  Citations

• Identification of Escherichia coli ubiB, a Gene Required for the First Monooxygenase Step in Ubiquinone Biosynthesis

  Wayne W. Poon;Diana E. Davis;Huan T. Ha;Tanya Jonassen

  163
  Citations

• Complementation of coq3 mutant yeast by mitochondrial targeting of the Escherichia coli UbiG polypeptide: evidence that UbiG catalyzes both O-methylation steps in ubiquinone biosynthesis.

  Adam Y. Hsu;Wayne W. Poon;Jennifer A. Shepherd;David C. Myles

  162
  Citations

• Expression of the human atypical kinase ADCK3 rescues coenzyme Q biosynthesis and phosphorylation of Coq polypeptides in yeast coq8 mutants.

  Letian X. Xie;Edward J. Hsieh;Shota Watanabe;Christopher M. Allan

  151
  Citations

• Lipidomic analysis and electron transport chain activities in C57BL/6J mouse brain mitochondria.

  Michael A. Kiebish;Xianlin Han;Hua Cheng;Adam Lunceford

  145
  Citations