Peter A. Edwards

Overview

Best Publications

• Atherosclerosis: basic mechanisms. Oxidation, inflammation, and genetics.

  Judith A. Berliner;Mohamad Navab;Alan M. Fogelman;Joy S. Frank

  2652
  Citations

• A PPARγ-LXR-ABCA1 Pathway in Macrophages Is Involved in Cholesterol Efflux and Atherogenesis

  Ajay Chawla;William A. Boisvert;Chih Hao Lee;Bryan A. Laffitte

  1704
  Citations

• Malondialdehyde alteration of low density lipoproteins leads to cholesteryl ester accumulation in human monocyte-macrophages

  Alan M. Fogelman;Ishaiahu Shechter;Janet Seager;Martha Hokom

  1224
  Citations

• Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXRα

  Asha Venkateswaran;Bryan A. Laffitte;Sean B. Joseph;Puiying A. Mak

  1179
  Citations

• Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor

  Heidi R. Kast;Bryan Goodwin;Paul T. Tarr;Stacey A. Jones

  1114
  Citations

• Pleiotropic Roles of Bile Acids in Metabolism

  Thomas Q. de Aguiar Vallim;Elizabeth J. Tarling;Peter A. Edwards

  1110
  Citations

• The Yin and Yang of Oxidation in the Development of the Fatty Streak: A Review Based on the 1994 George Lyman Duff Memorial Lecture

  M Navab;J A Berliner;A D Watson;S Y Hama

  1025
  Citations

• ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation.

  Matthew A. Kennedy;Gabriel C. Barrera;Kotoka Nakamura;Ángel Baldán

  1025
  Citations

• Trimethylamine-N-Oxide, a Metabolite Associated with Atherosclerosis, Exhibits Complex Genetic and Dietary Regulation

  Brian J. Bennett;Thomas Q. de Aguiar Vallim;Zeneng Wang;Diana M. Shih

  974
  Citations

• Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice

  Yanqiao Zhang;Florence Ying Lee;Gabriel Barrera;Hans Lee

  853
  Citations

• LXR Signaling Couples Sterol Metabolism to Proliferation in the Acquired Immune Response

  Steven J. Bensinger;Michelle N. Bradley;Sean B. Joseph;Noam Zelcer

  769
  Citations

• Apoptotic Cells Promote Their Own Clearance and Immune Tolerance through Activation of the Nuclear Receptor LXR

  Noelia A-Gonzalez;Steven J. Bensinger;Cynthia Hong;Susana Beceiro

  634
  Citations

• Sterols and Isoprenoids: Signaling Molecules Derived from the Cholesterol Biosynthetic Pathway

  Peter A. Edwards;Johan Ericsson

  593
  Citations

• Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols

  Asha Venkateswaran;Joyce J. Repa;Jean Marc A Lobaccaro;Amy Bronson

  473
  Citations

• BAREing it all: the adoption of LXR and FXR and their roles in lipid homeostasis.

  Peter A. Edwards;Heidi R. Kast;Andrew M. Anisfeld

  463
  Citations

• A Chemical, Genetic, and Structural Analysis of the Nuclear Bile Acid Receptor FXR

  Michael Downes;Mark A. Verdecia;A.J. Roecker;Robert Hughes

  451
  Citations

• Peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α) regulates triglyceride metabolism by activation of the nuclear receptor FXR

  Yanqiao Zhang;Lawrence W. Castellani;Christopher J. Sinal;Frank J. Gonzalez

  446
  Citations

• FXR, a multipurpose nuclear receptor.

  Florence Y. Lee;Hans Lee;Melissa L. Hubbert;Peter A. Edwards

  433
  Citations

• Regulation of gene expression by SREBP and SCAP.

  Peter A Edwards;David Tabor;Heidi R Kast;Asha Venkateswaran

  426
  Citations

• Farnesoid X-Activated Receptor Induces Apolipoprotein C-II Transcription: a Molecular Mechanism Linking Plasma Triglyceride Levels to Bile Acids

  Heidi Rachelle Kast;Catherine M. Nguyen;Christopher J. Sinal;Stacey A. Jones

  402
  Citations