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Chemistry

D-Index
77
Citations
20038
World Ranking
4053
National Ranking
1285

Overview

Vicki H. Wysocki is affiliated with The Ohio State University in the United States. Their research spans multiple areas within biochemistry, genetics, and molecular biology, with a significant emphasis on chemistry.

The primary fields of study for Wysocki include Biochemistry, Genetics and Molecular Biology and Chemistry. More specifically, their subfields of research cover Molecular Biology, Spectroscopy, and Materials Chemistry, along with notable work related to Ecology and Computational Mechanics.

The key topics of their research involve Mass Spectrometry Techniques and Applications, RNA and protein synthesis mechanisms, Protein Structure and Dynamics, Enzyme Structure and Function, Advanced Proteomics Techniques and Applications, Analytical Chemistry and Chromatography, and Metabolomics and Mass Spectrometry Studies.

Wysocki has contributed widely to the scientific literature, publishing in a range of venues with frequent appearances in bioRxiv (Cold Spring Harbor Laboratory), Journal of the American Society for Mass Spectrometry, and Analytical Chemistry. Other notable venues include Proceedings of the National Academy of Sciences and Nucleic Acids Research.

Selected recent publications of Wysocki include:

  • De novo design of protein logic gates (2020, Science)
  • Rapid online buffer exchange for screening of proteins, protein complexes and cell lysates by native mass spectrometry (2020, Nature Protocols)
  • De novo design of transmembrane β barrels (2021, Science)
  • Native Mass Spectrometry: Recent Progress and Remaining Challenges (2022, Annual Review of Biophysics)
  • Variable-Temperature Electrospray Ionization for Temperature-Dependent Folding/Refolding Reactions of Proteins and Ligand Binding (2021, Analytical Chemistry)

Their collaborative network includes frequent co-authors such as Sophie R. Harvey, Andrew Norris, Florian Büsch, David Baker, and Dalton T. Snyder, reflecting ongoing partnerships in complex research projects.

Best Publications

  • Mobile and localized protons: a framework for understanding peptide dissociation

    Vicki H. Wysocki;George Tsaprailis;Lori L. Smith;Linda A. Breci

  • Influence of Peptide Composition, Gas-Phase Basicity, and Chemical Modification on Fragmentation Efficiency: Evidence for the Mobile Proton Model

    Ashok R. Dongré;Jennifer L. Jones;Árpád Somogyi,⊥,‡ and;Vicki H. Wysocki

  • How many human proteoforms are there

    Ruedi Aebersold;Jeffrey N. Agar;I. Jonathan Amster;Mark S. Baker

  • Interface Dipoles Arising from Self-Assembled Monolayers on Gold: UV−Photoemission Studies of Alkanethiols and Partially Fluorinated Alkanethiols

    Dana M. Alloway;Michael Hofmann;Michael Hofmann;Darrin L. Smith;Nadine E. Gruhn

  • Mass spectrometry of peptides and proteins.

    Vicki H. Wysocki;Katheryn A. Resing;Qingfen Zhang;Guilong Cheng

  • Influence of Secondary Structure on the Fragmentation of Protonated Peptides

    George Tsaprailis;Hari Nair;Árpád Somogyi;Vicki H. Wysocki

  • Cleavage N-Terminal to Proline: Analysis of a Database of Peptide Tandem Mass Spectra

    Linda A. Breci;David L. Tabb;John R. Yates;Vicki H. Wysocki

  • A Linguistic Comparison of Letters of Recommendation for Male and Female Chemistry and Biochemistry Job Applicants

    Toni Schmader;Jessica Whitehead;Vicki H. Wysocki

  • Surface-induced dissociation: an effective tool to probe structure, energetics and fragmentation mechanisms of protonated peptides.

    Ashok R. Dongré;Árpád Somogyi;Vicki H. Wysocki

  • Statistical characterization of ion trap tandem mass spectra from doubly charged tryptic peptides.

    David L. Tabb;Lori L. Smith;Linda A. Breci;Vicki H. Wysocki

  • Internal energy distributions of isolated ions after activation by various methods

    Vicki H. Wysocki;Hilkka I. Kenttämaa;R.Graham Cooks

  • Statistical characterization of the charge state and residue dependence of low-energy CID peptide dissociation patterns.

    Yingying Huang;Joseph M. Triscari;George C. Tseng;Ljiljana Pasa-Tolic

  • Fragmentation of protonated peptides: surface-induced dissociation in conjunction with a quantum mechanical approach.

    Ashley L. McCormack;Arpad. Somogyi;Ashok R. Dongre;Vicki H. Wysocki

  • Selective gas-phase cleavage at the peptide bond C-terminal to aspartic acid in fixed-charge derivatives of Asp-containing peptides.

    Chungang Gu;George Tsaprailis;Linda Breci;Vicki H. Wysocki

  • Small-Molecule Analysis with Silicon-Nanoparticle-Assisted Laser Desorption/Ionization Mass Spectrometry

    Xiujuan Wen;Shai Dagan;Vicki H. Wysocki

  • Reactions of ions with organic surfaces

    R. G. Cooks;T. Ast;T. Pradeep;V. H. Wysocki

  • Sequence Dependence of Peptide Fragmentation Efficiency Curves Determined by Electrospray Ionization/Surface-Induced Dissociation Mass Spectrometry

    Jennifer L. Jones;Ashok R. Dongre;Arpad Somogyi;Vicki H. Wysocki

  • Influence of basic residue content on fragment ion peak intensities in low-energy collision-induced dissociation spectra of peptides.

    David L. Tabb;Yingying Huang;Vicki H. Wysocki;John R. Yates

  • Programmable design of orthogonal protein heterodimers

    Zibo Chen;Scott E. Boyken;Mengxuan Jia;Florian Busch

  • Reductive Defluorination of Perfluorooctane Sulfonate

    Valeria Ochoa-Herrera;Reyes Sierra-Alvarez;Arpad Somogyi;Neil E. Jacobsen

  • Refining the model for selective cleavage at acidic residues in arginine-containing protonated peptides

    George Tsaprailis;Árpád Somogyi;Eugene N. Nikolaev;Vicki H. Wysocki

Frequent Co-Authors

David Baker
David Baker University of Washington
Ljiljana Paša-Tolić
Ljiljana Paša-Tolić Environmental Molecular Sciences Laboratory
Hilkka I. Kenttämaa
Hilkka I. Kenttämaa Purdue University West Lafayette
R. Graham Cooks
R. Graham Cooks Purdue University West Lafayette
John R. Yates
John R. Yates Scripps Research Institute
David L. Tabb
David L. Tabb Stellenbosch University
Alan G. Barbour
Alan G. Barbour University of California, Irvine
T. Randall Lee
T. Randall Lee University of Houston
Jacques Schrenzel
Jacques Schrenzel University of Geneva
Thalappil Pradeep
Thalappil Pradeep Indian Institute of Technology Madras

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