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Medicine

D-Index
105
Citations
38498
World Ranking
6803
National Ranking
657

Overview

Helen J. Lachmann is affiliated with University College London in the United Kingdom. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a significant focus on areas such as Molecular Biology, Nephrology, Immunology, Rheumatology, and Genetics.

Their work addresses multiple topics, including:

  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Parathyroid Disorders and Treatments
  • Inflammasome and immune disorders
  • Neuroendocrine Tumor Research Advances
  • Medical Imaging and Pathology Studies
  • Autoimmune and Inflammatory Disorders Research
  • Peptidase Inhibition and Analysis

Helen J. Lachmann has contributed to recent publications in high-impact journals. Notable papers include:

  • "Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease," 2020, New England Journal of Medicine
  • "Familial Mediterranean fever, from pathogenesis to treatment: a contemporary review," 2020, TURKISH JOURNAL OF MEDICAL SCIENCES
  • "Impact of Earlier Diagnosis in Cardiac ATTR Amyloidosis Over the Course of 20 Years," 2022, Circulation
  • "Effect of Canakinumab vs Placebo on Survival Without Invasive Mechanical Ventilation in Patients Hospitalized With Severe COVID-19," 2021, JAMA
  • "Epidemiologic and Survival Trends in Amyloidosis, 1987-2019," 2020, New England Journal of Medicine

Frequent co-authors collaborating with Lachmann feature:

  • Philip N. Hawkins
  • Julian D. Gillmore
  • Ashutosh Wechalekar
  • Carol Whelan
  • Ana Martinez-Naharro

Their research outputs are often published in venues such as:

  • European Heart Journal
  • Circulation
  • European Journal of Heart Failure
  • British Journal of Haematology
  • Blood

Best Publications

  • Nonbiopsy Diagnosis of Cardiac Transthyretin Amyloidosis.

    Julian D. Gillmore;Mathew S. Maurer;Rodney H. Falk;Giampaolo Merlini

  • Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease.

    David B. Beck;Marcela A. Ferrada;Keith A. Sikora;Amanda K. Ombrello

  • Natural history and outcome in systemic AA amyloidosis.

    Helen J Lachmann;Hugh J B Goodman;Janet A Gilbertson;J Ruth Gallimore

  • Use of canakinumab in the cryopyrin-associated periodic syndrome.

    Helen J Lachmann;Isabelle Kone-Paut;Jasmin B Kuemmerle-Deschner;Kieron S Leslie

  • Misdiagnosis of hereditary amyloidosis as AL (primary) amyloidosis.

    Helen J Lachmann;David R Booth;Susanne E Booth;Alison Bybee

  • Spectrum of clinical features in Muckle‐Wells syndrome and response to anakinra

    Philip N. Hawkins;Helen J. Lachmann;Ebun Aganna;Michael F. McDermott

  • Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis

    M. B. Pepys;J. Herbert;W. L. Hutchinson;G. A. Tennent

  • The European Society for Immunodeficiencies (ESID) Registry Working Definitions for the Clinical Diagnosis of Inborn Errors of Immunity

    Markus G. Seidel;Gerhard Kindle;Benjamin Gathmann;Isabella Quinti

  • Prognostic Value of Late Gadolinium Enhancement Cardiovascular Magnetic Resonance in Cardiac Amyloidosis

    Marianna Fontana;Silvia Pica;Patricia Reant;Amna Abdel-Gadir

  • A new staging system for cardiac transthyretin amyloidosis

    Julian D Gillmore;Thibaud Damy;Marianna Fontana;Matthew Hutchinson

  • Interleukin-1-receptor antagonist in the Muckle-Wells syndrome.

    Philip N. Hawkins;Helen J. Lachmann;Michael F. McDermott

  • T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells

    Giuseppina Arbore;Erin E. West;Rosanne Spolski;Avril A. B. Robertson

  • Outcome in systemic AL amyloidosis in relation to changes in concentration of circulating free immunoglobulin light chains following chemotherapy.

    Helen J. Lachmann;Ruth Gallimore;Julian D. Gillmore;Hugh D. Carr-Smith

  • Classification criteria for autoinflammatory recurrent fevers

    Marco Gattorno;Michael Hofer;Silvia Federici;Federica Vanoni

  • Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis.

    Ebun Aganna;Fabio Martinon;Philip N. Hawkins;John B. Ross

  • Canakinumab for the Treatment of Autoinflammatory Recurrent Fever Syndromes

    Fabrizio De Benedetti;Marco Gattorno;Jordi Anton;Eldad Ben-Chetrit

  • Treatment of autoinflammatory diseases: results from the Eurofever Registry and a literature review

    Nienke Ter Haar;Helen Lachmann;Seza Özen;Pat Woo

  • The evaluation of monoclonal gammopathy of renal significance: a consensus report of the International Kidney and Monoclonal Gammopathy Research Group.

    Nelson Leung;Frank Bridoux;Vecihi Batuman;Aristeidis Chaidos

  • Clinical and subclinical inflammation in patients with familial Mediterranean fever and in heterozygous carriers of MEFV mutations

    H. J. Lachmann;B. Şengül;T. U. Yavuzşen;D. R. Booth

  • Native T1 mapping in transthyretin amyloidosis

    Marianna Fontana;Sanjay M. Banypersad;Thomas A. Treibel;Viviana Maestrini

Frequent Co-Authors

Julian D. Gillmore
Julian D. Gillmore University College London
Marco Gattorno
Marco Gattorno Istituto Giannina Gaslini
Philip N. Hawkins
Philip N. Hawkins University College London
Anna Simon
Anna Simon Christian Medical College & Hospital
Seza Ozen
Seza Ozen Hacettepe University
James C. Moon
James C. Moon University College London
Giampaolo Merlini
Giampaolo Merlini University of Pavia
Ahmet Gül
Ahmet Gül Istanbul University
Mark B. Pepys
Mark B. Pepys University College London
Claudia Kemper
Claudia Kemper National Institutes of Health

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