Herren Wu mostly deals with Molecular biology, Antibody, Monoclonal antibody, Immunology and Antigen. His Molecular biology study integrates concerns from other disciplines, such as Receptor, Biochemistry, Ligand, Antibody-dependent cell-mediated cytotoxicity and Immunoglobulin light chain. His studies in Receptor integrate themes in fields like Mutant, Growth inhibition, Binding site and Cell biology.
The various areas that Herren Wu examines in his Antibody study include Palivizumab and Virology. His research in Monoclonal antibody intersects with topics in Avidity, Affinity maturation and Genomic library. Herren Wu works mostly in the field of Antigen, limiting it down to concerns involving Computational biology and, occasionally, Peptide library, Complementarity determining region and Immunogenicity.
His scientific interests lie mostly in Antibody, Molecular biology, Monoclonal antibody, Immunology and Antigen. In his study, which falls under the umbrella issue of Antibody, Function is strongly linked to Nucleic acid. Herren Wu interconnects Biophysics, Antibody-dependent cell-mediated cytotoxicity, Immunoglobulin light chain, Cell biology and Phage display in the investigation of issues within Molecular biology.
His Monoclonal antibody research incorporates elements of Affinity maturation and Cytotoxicity. Herren Wu works mostly in the field of Immunology, limiting it down to topics relating to Receptor and, in certain cases, Immune system. His Antigen research includes elements of Complementarity determining region and Computational biology.
Herren Wu mainly investigates Antibody, Monoclonal antibody, Epitope, Cell biology and Biochemistry. His work deals with themes such as Molecular biology, Receptor, Antigen and Cytotoxicity, which intersect with Antibody. His Molecular biology research incorporates themes from Immunoglobulin light chain, Biophysics, Computational biology and Chinese hamster.
In his study, Schlafen family member 11 and Click chemistry is inextricably linked to Cancer cell, which falls within the broad field of Monoclonal antibody. The study incorporates disciplines such as Monoclonal, Internalization, Cancer research and Virology in addition to Epitope. His work in the fields of Cell biology, such as Effector, overlaps with other areas such as CXC chemokine receptors.
Herren Wu mainly focuses on Antibody, Biochemistry, Monoclonal antibody, Epitope and Epitope mapping. His work carried out in the field of Antibody brings together such families of science as Receptor, Computational biology, Molecular biology and Antigen. His biological study spans a wide range of topics, including Enzyme, Docking, Macromolecular docking and Effector.
His study looks at the relationship between Antigen and fields such as Immune system, as well as how they intersect with chemical problems. His Monoclonal antibody study is related to the wider topic of Immunology. The concepts of his Epitope mapping study are interwoven with issues in Paratope and Mechanism of action.
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Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE.
Jane Tian;Ana Maria Avalos;Su-Yau Mao;Bo Chen.
Nature Immunology (2007)
Humanization of a murine monoclonal antibody by simultaneous optimization of framework and CDR residues.
Herren Wu;Ying Nie;William D Huse;Jeffry D Watkins.
Journal of Molecular Biology (1999)
Properties of Human IgG1s Engineered for Enhanced Binding to the Neonatal Fc Receptor (FcRn)
William F. Dall'Acqua;Peter A. Kiener;Herren Wu.
Journal of Biological Chemistry (2006)
MEDI-563, a humanized anti-IL-5 receptor alpha mAb with enhanced antibody-dependent cell-mediated cytotoxicity function.
Roland Kolbeck;Alexander Kozhich;Masamichi Koike;Li Peng.
The Journal of Allergy and Clinical Immunology (2010)
Development of motavizumab, an ultra-potent antibody for the prevention of respiratory syncytial virus infection in the upper and lower respiratory tract.
Herren Wu;David S. Pfarr;Syd Johnson;Yambasu A. Brewah.
Journal of Molecular Biology (2007)
Increasing the Affinity of a Human IgG1 for the Neonatal Fc Receptor: Biological Consequences
William F. Dall’ Acqua;Robert M. Woods;E. Sally Ward;Susan R. Palaszynski.
Journal of Immunology (2002)
Stepwise in vitro affinity maturation of Vitaxin, an αvβ3-specific humanized mAb
Herren Wu;Gregory Beuerlein;Ying Nie;Heidi Smith.
Proceedings of the National Academy of Sciences of the United States of America (1998)
Ultra-potent antibodies against respiratory syncytial virus: effects of binding kinetics and binding valence on viral neutralization
Herren Wu;David S. Pfarr;Ying Tang;Ling-Ling An.
Journal of Molecular Biology (2005)
A Biparatopic HER2-Targeting Antibody-Drug Conjugate Induces Tumor Regression in Primary Models Refractory to or Ineligible for HER2-Targeted Therapy
John Y. Li;Samuel R. Perry;Vanessa Muniz-Medina;Xinzhong Wang.
Cancer Cell (2016)
Modulation of the effector functions of a human IgG1 through engineering of its hinge region.
William F. Dall’Acqua;Kimberly E. Cook;Melissa M. Damschroder;Robert M. Woods.
Journal of Immunology (2006)
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