World's Best Scientists 2026 revealed!
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Biology and Biochemistry
Germany
2025

D-Index & Metrics

Immunology

D-Index
105
Citations
47231
World Ranking
583
National Ranking
347

Research.com Recognitions

  • 2025 - Research.com Biology and Biochemistry in Germany Leader Award

Overview

Alejandro Aruffo is affiliated with Bristol-Myers Squibb in Germany, where they engage in scientific research. Their professional work is positioned within this institution, contributing to the broader field of biomedical or pharmaceutical sciences typical of the affiliation.

Currently, there is no publicly available data listing specific research papers authored by Alejandro Aruffo, nor detailed information on their research topics or specific fields of study. Additionally, there is no information on frequent co-authors or typical publication venues associated with their work.

Due to the lack of detailed publication records and topic areas, it is not possible to outline particular subfields or thematic topics that define their scientific contributions. Moreover, no data is available regarding book publications or academic awards.

The absence of detailed records suggests either a limited public profile in academic publishing or that their work may primarily contribute through other channels such as industry research, internal development projects, or proprietary studies within Bristol-Myers Squibb.

Best Publications

  • CD44 is the principal cell surface receptor for hyaluronate.

    Alejandro Aruffo;Ivan Stamenkovic;Michael Melnick;Charles B. Underhill

  • Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways.

    Christian P. Larsen;Eric T. Elwood;Diane Z. Alexander;Shannon C. Ritchie

  • Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation.

    Peter S. Linsley;William Brady;Laura Grosmaire;Alejandro Aruffo

  • Recognition by ELAM-1 of the sialyl-Lex determinant on myeloid and tumor cells

    Gerd Walz;Alejandro Aruffo;Waldemar Kolanus;Michael Bevilacqua

  • Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure.

    Brian Seed;Alejandro Aruffo

  • Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system

    Alejandro Aruffo;Brian Seed

  • A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells

    Randolph J. Noelle;Meenakshi Roy;David M. Shepherd;Ivan Stamenkovic

  • Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

    Ignacio Melero;Walter W. Shuford;Stephanie Ashe Newby;Alejandro Aruffo

  • The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome

    Alejandro Aruffo;Alejandro Aruffo;Mary Farrington;Diane Hollenbaugh;Xu Li

  • 4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses.

    Walter W. Shuford;Kerry Klussman;Douglas D. Tritchler;Deryk T. Loo

  • The human T cell antigen gp39, a member of the TNF gene family, is a ligand for the CD40 receptor: expression of a soluble form of gp39 with B cell co-stimulatory activity.

    D. Hollenbaugh;L.S. Grosmaire;C.D. Kullas;N.J. Chalupny

  • The hematopoietic and epithelial forms of CD44 are distinct polypeptides with different adhesion potentials for hyaluronate-bearing cells.

    I. Stamenkovic;A. Aruffo;M. Amiot;B. Seed

  • IMMUNE REGULATION BY CD40 AND ITS LIGAND GP39

    Teresa M. Foy;Alejandro Aruffo;Jürgen Bajorath;Janet E. Buhlmann

  • Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40

    Fiona H. Durie;Roy A. Fava;Teresa M. Foy;Alejandro Aruffo

  • CD40-CD40 ligand interactions in experimental allergic encephalomyelitis and multiple sclerosis

    Koen Gerritse;Jon D. Laman;Randolph J. Noelle;Alejandro Aruffo

  • Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: implications for the regulation of apoptosis in neutrophils.

    W C Liles;P A Kiener;J A Ledbetter;A Aruffo

  • Heparin oligosaccharides bind L- and P-selectin and inhibit acute inflammation

    RM Nelson;O Cecconi;WG Roberts;A Aruffo

  • gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory.

    Teresa M. Foy;Jon D. Laman;Jeffrey A. Ledbetter;Alejandro Aruffo

  • Expression cloning of an adenylate cyclase-coupled calcitonin receptor.

    Herbert Y. Lin;Tonja L. Harris;Merilee S. Flannery;Alejandro Aruffo

  • Differential costimulatory effects of adhesion molecules B7, ICAM-1, LFA-3, and VCAM-1 on resting and antigen-primed CD4+ T lymphocytes.

    N K Damle;K Klussman;P S Linsley;A Aruffo

  • Expression of functional CD40 by vascular endothelial cells.

    Diane Hollenbaugh;Nicole Mischel-Petty;Caroline P. Edwards;Jan C. Simon

Frequent Co-Authors

Diane Hollenbaugh
Diane Hollenbaugh Bonum Therapeutics
Jeffrey A. Ledbetter
Jeffrey A. Ledbetter University of Washington
Jürgen Bajorath
Jürgen Bajorath University of Bonn
Peter S. Linsley
Peter S. Linsley Benaroya Research Institute
Hans D. Ochs
Hans D. Ochs University of Washington
Randolph J. Noelle
Randolph J. Noelle Dartmouth College
David Simmons
David Simmons Western Sydney University
Ivan Stamenkovic
Ivan Stamenkovic Harvard University
Shigeaki Nonoyama
Shigeaki Nonoyama National Defense Medical College
Brian Seed
Brian Seed Harvard University

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