H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 103 Citations 81,541 256 World Ranking 608 National Ranking 393

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Immune system

Peter S. Linsley mainly investigates Cell biology, T cell, CD28, Immunology and Molecular biology. His research integrates issues of Cell, Receptor, RNA interference, microRNA and Gene silencing in his study of Cell biology. Peter S. Linsley has included themes like B-cell receptor and CD80, CD40 in his T cell study.

His CD28 research includes themes of T lymphocyte and Antigen presentation. His Molecular biology research focuses on Transfection and how it connects with Vector, Recombinant DNA, Phenotype and Cell growth. His research in Antigen-presenting cell tackles topics such as IL-2 receptor which are related to areas like Interleukin 21.

His most cited work include:

  • Gene expression profiling predicts clinical outcome of breast cancer (8278 citations)
  • Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs (4052 citations)
  • A microRNA component of the p53 tumour suppressor network (2244 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Molecular biology, T cell, Antigen, Immunology and CD28. Peter S. Linsley combines subjects such as Cytotoxic T cell, Receptor and Cell biology with his study of T cell. His study in Cell biology is interdisciplinary in nature, drawing from both Gene silencing, microRNA, RNA interference and Transfection.

The Antigen study which covers Monoclonal antibody that intersects with Lung. His biological study spans a wide range of topics, including In vivo, Blockade and Transplantation. His studies deal with areas such as T lymphocyte, CD80, CD40, Major histocompatibility complex and Antigen presentation as well as CD28.

He most often published in these fields:

  • Molecular biology (30.21%)
  • T cell (30.51%)
  • Antigen (27.19%)

What were the highlights of his more recent work (between 2004-2020)?

  • microRNA (5.74%)
  • RNA interference (6.65%)
  • Small interfering RNA (6.65%)

In recent papers he was focusing on the following fields of study:

MicroRNA, RNA interference, Small interfering RNA, Gene silencing and Cell biology are his primary areas of study. The concepts of his microRNA study are interwoven with issues in Cancer research, Phenotype, Carcinogenesis, Messenger RNA and Cell cycle. His research investigates the link between RNA interference and topics such as Genetic screen that cross with problems in Suicide gene.

His Trans-acting siRNA study in the realm of Small interfering RNA interacts with subjects such as Midbody. His work deals with themes such as Endoreduplication, Molecular biology and Gene expression profiling, which intersect with Cell biology. Specifically, his work in Antigen is concerned with the study of CD28.

Between 2004 and 2020, his most popular works were:

  • Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs (4052 citations)
  • A microRNA component of the p53 tumour suppressor network (2244 citations)
  • CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms (1178 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Peter S. Linsley mainly focuses on microRNA, Cell biology, RNA interference, Gene silencing and Small interfering RNA. His microRNA research integrates issues from Cancer research, Gene expression, Carcinogenesis, Downregulation and upregulation and Cell cycle. His research in Cell biology intersects with topics in Myeloid, Transfection, Molecular biology, Messenger RNA and Autoimmunity.

His Molecular biology study incorporates themes from CD3 and Phosphorylation. His Gene silencing study necessitates a more in-depth grasp of Genetics. His studies in Small interfering RNA integrate themes in fields like Small hairpin RNA, RNA silencing and Bioinformatics.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Gene expression profiling predicts clinical outcome of breast cancer

Laura J. van 't Veer;Hongyue Dai;Marc J. van de Vijver;Yudong D. He.
Nature (2002)

10936 Citations

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

Lee P. Lim;Nelson C. Lau;Philip Garrett-Engele;Andrew Grimson.
Nature (2005)

5497 Citations

A microRNA component of the p53 tumour suppressor network

Lin He;Xingyue He;Xingyue He;Lee P. Lim;Elisa de Stanchina;Elisa de Stanchina.
Nature (2007)

3088 Citations

Expression profiling reveals off-target gene regulation by RNAi

Aimee L Jackson;Steven R Bartz;Janell Schelter;Sumire V Kobayashi.
Nature Biotechnology (2003)

2839 Citations

CTLA-4 can function as a negative regulator of T cell activation

Theresa L. Walunas;Deborah J. Lenschow;Christina Y. Bakker;Peter S. Linsley.
Immunity (1994)

2196 Citations

CTLA-4 is a second receptor for the B cell activation antigen B7.

Peter S. Linsley;William Brady;Mark Urnes;Laura S. Grosmaire.
Journal of Experimental Medicine (1991)

1957 Citations

Genetics of gene expression surveyed in maize, mouse and man

Eric E. Schadt;Stephanie A. Monks;Thomas A. Drake;Aldons J. Lusis.
Nature (2003)

1815 Citations

Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways.

Christian P. Larsen;Eric T. Elwood;Diane Z. Alexander;Shannon C. Ritchie.
Nature (1996)

1675 Citations

The role of the CD28 receptor during T cell responses to antigen.

Peter S. Linsley;Jeffrey A. Ledbetter.
Annual Review of Immunology (1993)

1642 Citations

CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms

Richard V. Parry;Jens M. Chemnitz;Kenneth A. Frauwirth;Anthony R. Lanfranco.
Molecular and Cellular Biology (2005)

1641 Citations

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