H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Immunology D-index 112 Citations 40,120 344 World Ranking 182 National Ranking 121
Medicine D-index 119 Citations 49,209 423 World Ranking 1613 National Ranking 968

Research.com Recognitions

Awards & Achievements

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Immune system
  • Gene

Mohamed H. Sayegh mainly investigates Immunology, Transplantation, T cell, Immune tolerance and Immune system. His work deals with themes such as Cytotoxic T cell and Blockade, which intersect with Immunology. His study in Cytotoxic T cell is interdisciplinary in nature, drawing from both Proinflammatory cytokine, Haematopoiesis, CD8 and Cytokine.

Within one scientific family, he focuses on topics pertaining to Programmed Cell Death 1 Ligand 2 Protein under Blockade, and may sometimes address concerns connected to Insulitis and Nod. His research investigates the connection between Transplantation and topics such as In vivo that intersect with issues in CD40. His T cell research integrates issues from Experimental autoimmune encephalomyelitis, B7-H1 Antigen, Macrophage and Immunotherapy.

His most cited work include:

  • Endothelial-to-mesenchymal transition contributes to cardiac fibrosis (1490 citations)
  • Identification of cells initiating human melanomas (1170 citations)
  • Oral Tolerance: Immunologic Mechanisms and Treatment of Animal and Human Organ-Specific Autoimmune Diseases by Oral Administration of Autoantigens (854 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Immunology, Transplantation, T cell, Immune system and Cell biology. Mohamed H. Sayegh focuses mostly in the field of Immunology, narrowing it down to matters related to Blockade and, in some cases, CD154. His Transplantation study deals with In vivo intersecting with In vitro.

Mohamed H. Sayegh works mostly in the field of T cell, limiting it down to topics relating to Cytotoxic T cell and, in certain cases, CD8, as a part of the same area of interest. His study ties his expertise on Immunotherapy together with the subject of Immune tolerance. His Internal medicine study frequently intersects with other fields, such as Endocrinology.

He most often published in these fields:

  • Immunology (66.61%)
  • Transplantation (43.19%)
  • T cell (25.58%)

What were the highlights of his more recent work (between 2008-2020)?

  • Immunology (66.61%)
  • Transplantation (43.19%)
  • T cell (25.58%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Immunology, Transplantation, T cell, Internal medicine and Immune system. The Immunology study which covers Cytotoxic T cell that intersects with Cancer research. The study incorporates disciplines such as Receptor, Immunosuppression and Cell biology, Effector in addition to Transplantation.

His research integrates issues of Molecular biology, Blockade, Immune tolerance and Alloimmunity in his study of T cell. His studies deal with areas such as Endocrinology and Cardiology as well as Internal medicine. The concepts of his Immune system study are interwoven with issues in Proinflammatory cytokine, Mesenchymal stem cell and Cytokine.

Between 2008 and 2020, his most popular works were:

  • Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice (329 citations)
  • Immunomodulatory function of bone marrow-derived mesenchymal stem cells in experimental autoimmune type 1 diabetes. (311 citations)
  • Costimulatory pathways in transplantation: challenges and new developments. (159 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Immune system
  • Gene

His primary areas of investigation include Immunology, Transplantation, T cell, Blockade and Cell biology. His Immunology research includes elements of Signal transduction, Mesenchymal stem cell and Heart transplantation. His study in Transplantation is interdisciplinary in nature, drawing from both Immunosuppression, Tolerance induction, Haematopoiesis and Islet.

Mohamed H. Sayegh usually deals with T cell and limits it to topics linked to Immune tolerance and Regulatory B cells, FOXP3 and IL-2 receptor. His Blockade study combines topics from a wide range of disciplines, such as Interleukin 17 and In vivo. His study looks at the relationship between Cell biology and fields such as Antigen, as well as how they intersect with chemical problems.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

Elisabeth M Zeisberg;Oleg Tarnavski;Michael Zeisberg;Adam L Dorfman.
Nature Medicine (2007)

1974 Citations

Identification of cells initiating human melanomas

Tobias Schatton;George F. Murphy;Natasha Y. Frank;Kazuhiro Yamaura.
Nature (2008)

1607 Citations

Tissue expression of PD-L1 mediates peripheral T cell tolerance

Mary E. Keir;Spencer C. Liang;Indira Guleria;Yvette E. Latchman.
Journal of Experimental Medicine (2006)

1131 Citations

Oral Tolerance: Immunologic Mechanisms and Treatment of Animal and Human Organ-Specific Autoimmune Diseases by Oral Administration of Autoantigens

H. L. Weiner;A. Friedman;A. Miller;S. J. Khoury.
Annual Review of Immunology (1994)

1117 Citations

Delayed graft function in kidney transplantation.

Norberto Perico;Dario Cattaneo;Mohamed H Sayegh;Giuseppe Remuzzi.
The Lancet (2004)

1028 Citations

The Programmed Death-1 (PD-1) Pathway Regulates Autoimmune Diabetes in Nonobese Diabetic (NOD) Mice

Mohammed Javeed I. Ansari;Alan D. Salama;Alan D. Salama;Tanuja Chitnis;Tanuja Chitnis;R. Neal Smith.
Journal of Experimental Medicine (2003)

811 Citations

The Role of T-Cell Costimulatory Activation Pathways in Transplant Rejection

Mohamed H. Sayegh;Laurence A. Turka.
The New England Journal of Medicine (1998)

719 Citations

Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance.

Andrew D. Wells;Xian Chang Li;Yongsheng Li;Matthew C. Walsh.
Nature Medicine (1999)

683 Citations

ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma.

Natasha Y. Frank;Armen Margaryan;Ying Huang;Tobias Schatton.
Cancer Research (2005)

675 Citations

CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2.

Mohamed H. Sayegh;Enver Akalin;Wayne W. Hancock;Mary E. Russell.
Journal of Experimental Medicine (1995)

630 Citations

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