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Christian P. Larsen

Christian P. Larsen

D-Index & Metrics

Immunology

D-Index
95
Citations
36057
World Ranking
890
National Ranking
494

Medicine

D-Index
95
Citations
36126
World Ranking
9999
National Ranking
5147

Overview

Christian P. Larsen is affiliated with Emory University in the United States and has focused primarily on medical research with significant contributions in transplantation, infectious diseases, and immunology. Their work spans various subfields, including transplantation, infectious diseases, immunology, epidemiology, and surgery.

The main areas of research addressed by Larsen include renal transplantation outcomes and treatments, cytomegalovirus and herpesvirus research, immune cell function and interaction, SARS-CoV-2 and COVID-19 research, T-cell and B-cell immunology, COVID-19 clinical research studies, and Pneumocystis jirovecii pneumonia detection and treatment.

Frequent coauthors collaborating with Larsen are:

  • Geeta Karadkhele
  • Haydn Kissick
  • I.R. Badell
  • Aileen C. Johnson
  • Stephanie M. Pouch

Common publication venues where Larsen has published multiple articles include:

  • American Journal of Transplantation
  • Open Forum Infectious Diseases
  • Clinical Transplantation
  • Transplant Infectious Disease
  • Transplantation Direct

Examples of notable recent papers authored by Larsen include:

  • CD8+ T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor, 2022, Immunity
  • Phase 3 trial of human islet-after-kidney transplantation in type 1 diabetes, 2020, American Journal of Transplantation
  • Fecal microbiota transplantation promotes reduction of antimicrobial resistance by strain replacement, 2023, Science Translational Medicine
  • CMV high-risk status and posttransplant outcomes in kidney transplant recipients treated with belatacept, 2020, American Journal of Transplantation
  • Association between primary graft function and 5-year outcomes of islet allogeneic transplantation in type 1 diabetes: a retrospective, multicentre, observational cohort study in 1210 patients from the Collaborative Islet Transplant Registry, 2023, The Lancet Diabetes & Endocrinology

Larsen's research contributions have demonstrated engagement with clinical trial design, infectious disease control in transplant recipients, immune cell functionality, and long-term transplantation outcomes. The focus on cytomegalovirus, immune responses, and transplantation reflects a comprehensive approach integrating immunology with clinical patient care.

Best Publications

  • Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways.

    Christian P. Larsen;Eric T. Elwood;Diane Z. Alexander;Shannon C. Ritchie

  • mTOR regulates memory CD8 T-cell differentiation

    Koichi Araki;Alexandra P. Turner;Virginia Oliva Shaffer;Shivaprakash Gangappa

  • Rapid cloning of high-affinity human monoclonal antibodies against influenza virus

    Jens Wrammert;Kenneth Smith;Joe Miller;William A. Langley

  • A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study).

    F. Vincenti;B. Charpentier;Y. Vanrenterghem;L. Rostaing

  • Costimulation blockade with belatacept in renal transplantation.

    Flavio Vincenti;Christian Larsen;Antoine Durrbach;Thomas Wekerle

  • 4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses.

    Walter W. Shuford;Kerry Klussman;Douglas D. Tritchler;Deryk T. Loo

  • Improvement in outcomes of clinical islet transplantation: 1999-2010.

    Franca B. Barton;Michael R. Rickels;Rodolfo Alejandro;Bernhard J. Hering

  • Rational Development of LEA29Y (belatacept), a High‐Affinity Variant of CTLA4‐Ig with Potent Immunosuppressive Properties

    Christian P. Larsen;Thomas C. Pearson;Andrew B. Adams;Paul Tso

  • Migration and maturation of Langerhans cells in skin transplants and explants.

    C P Larsen;R M Steinman;M Witmer-Pack;D F Hankins

  • Belatacept and Long-Term Outcomes in Kidney Transplantation.

    Flavio Vincenti;Lionel Rostaing;Joseph Grinyo;Kim Rice

  • Heterologous immunity provides a potent barrier to transplantation tolerance.

    Andrew B. Adams;Matthew A. Williams;Thomas R. Jones;Nozomu Shirasugi

  • Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia

    Bernhard J. Hering;William R. Clarke;Nancy D. Bridges;Thomas L. Eggerman

  • Migration of dendritic leukocytes from cardiac allografts into host spleens. A novel pathway for initiation of rejection.

    C P Larsen;P J Morris;J M Austyn

  • Dendritic cell loss from nonlymphoid tissues after systemic administration of lipopolysaccharide, tumor necrosis factor, and interleukin 1.

    Justin A. Roake;Abdul S. Rao;Peter J. Morris;Christian P. Larsen

  • Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways.

    Kenneth Cardona;Gregory S Korbutt;Zvonimir Milas;James Lyon

  • Regulation of immunostimulatory function and costimulatory molecule (B7-1 and B7-2) expression on murine dendritic cells.

    C P Larsen;S C Ritchie;R Hendrix;P S Linsley

  • Transplantation tolerance induced by CTLA4-Ig.

    Thomas C. Pearson;Diane Z. Alexander;Kevin J. Winn;Peter S. Linsley

  • CD40-gp39 interactions play a critical role during allograft rejection. Suppression of allograft rejection by blockade of the CD40-gp39 pathway

    Christian P. Larsen;Diane Z. Alexander;Diane Hollenbaugh;Eric T. Elwood

  • Three-year outcomes from BENEFIT, a randomized, active-controlled, parallel-group study in adult kidney transplant recipients.

    F. Vincenti;C. P. Larsen;J. Alberu;B. Bresnahan

  • Functional expression of the costimulatory molecule, B7/BB1, on murine dendritic cell populations

    C P Larsen;S C Ritchie;T C Pearson;P S Linsley

Frequent Co-Authors

Thomas C. Pearson
Thomas C. Pearson Emory University
Allan D. Kirk
Allan D. Kirk Duke University
Mandy L. Ford
Mandy L. Ford Emory University
Flavio Vincenti
Flavio Vincenti University of California, San Francisco
Rafi Ahmed
Rafi Ahmed Emory University
Peter S. Linsley
Peter S. Linsley Benaroya Research Institute
Keith A. Reimann
Keith A. Reimann Harvard Medical School
Diane Hollenbaugh
Diane Hollenbaugh Bonum Therapeutics
Josep M. Grinyó
Josep M. Grinyó University of Barcelona

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