Christian P. Larsen mainly focuses on Immunology, Transplantation, Immune system, T cell and Immunosuppression. His Immunology research incorporates elements of Cytotoxic T cell and CD40. His study in CD40 is interdisciplinary in nature, drawing from both Allograft rejection, Blockade, In vivo and Effector.
His Transplantation study combines topics from a wide range of disciplines, such as Regimen and Tolerance induction. His Immune system research integrates issues from Organ transplantation and Heterologous. His research integrates issues of Cellular immunity and Cell biology in his study of T cell.
Christian P. Larsen mostly deals with Immunology, Transplantation, Belatacept, T cell and CD28. His Immunology study integrates concerns from other disciplines, such as Cytotoxic T cell, CD40 and Blockade. The various areas that Christian P. Larsen examines in his Blockade study include Cancer research, CD154, Monoclonal antibody and In vivo.
His research in Transplantation intersects with topics in Bone marrow, Immune tolerance and Islet. His study in Belatacept is interdisciplinary in nature, drawing from both Regimen, Immunosuppression, Abatacept and Urology. His T cell research is multidisciplinary, relying on both Major histocompatibility complex, Cytokine, Priming and Virology.
The scientist’s investigation covers issues in Belatacept, Immunology, Transplantation, Immunosuppression and Kidney transplantation. His research in Belatacept intersects with topics in Calcineurin, Renal function, Regimen, Urology and Abatacept. His Immunology study deals with Cytotoxic T cell intersecting with Toxicity and Cell biology.
As a member of one scientific family, he mostly works in the field of Transplantation, focusing on Diabetes mellitus and, on occasion, Clinical endpoint. The Immunosuppression study combines topics in areas such as Clinical trial, Randomization, Tacrolimus, Kidney and Antibody. His studies deal with areas such as Blockade and Cytokine as well as T cell.
Immunology, Belatacept, Transplantation, Immunosuppression and Abatacept are his primary areas of study. His work focuses on many connections between Immunology and other disciplines, such as Cytotoxic T cell, that overlap with his field of interest in CD8 and Toxicity. His Belatacept study combines topics in areas such as CD28, Cell, Tacrolimus and Renal function.
His Transplantation study is concerned with the field of Internal medicine as a whole. His Immunosuppression research integrates issues from Clinical trial, Surgery, Antibody and Urology. His Abatacept study combines topics from a wide range of disciplines, such as Pharmacology and Sirolimus.
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Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways.
Christian P. Larsen;Eric T. Elwood;Diane Z. Alexander;Shannon C. Ritchie.
Nature (1996)
mTOR regulates memory CD8 T-cell differentiation
Koichi Araki;Alexandra P. Turner;Virginia Oliva Shaffer;Shivaprakash Gangappa.
Nature (2009)
Rapid cloning of high-affinity human monoclonal antibodies against influenza virus
Jens Wrammert;Kenneth Smith;Joe Miller;William A. Langley.
Nature (2008)
Costimulation blockade with belatacept in renal transplantation.
Flavio Vincenti;Christian Larsen;Antoine Durrbach;Thomas Wekerle.
The New England Journal of Medicine (2005)
4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses.
Walter W. Shuford;Kerry Klussman;Douglas D. Tritchler;Deryk T. Loo.
Journal of Experimental Medicine (1997)
A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study).
F. Vincenti;B. Charpentier;Y. Vanrenterghem;L. Rostaing.
American Journal of Transplantation (2010)
Migration and maturation of Langerhans cells in skin transplants and explants.
C P Larsen;R M Steinman;M Witmer-Pack;D F Hankins.
Journal of Experimental Medicine (1990)
Improvement in outcomes of clinical islet transplantation: 1999-2010.
Franca B. Barton;Michael R. Rickels;Rodolfo Alejandro;Bernhard J. Hering.
Diabetes Care (2012)
Heterologous immunity provides a potent barrier to transplantation tolerance.
Andrew B. Adams;Matthew A. Williams;Thomas R. Jones;Nozomu Shirasugi.
Journal of Clinical Investigation (2003)
Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties.
Christian P. Larsen;Thomas C. Pearson;Andrew B. Adams;Paul Tso.
American Journal of Transplantation (2005)
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