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Molecular Biology

D-Index
82
Citations
18325
World Ranking
945
National Ranking
502

Overview

Robert A. Bambara is affiliated with the University of Rochester in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with notable work in molecular biology as a subfield. The scientist's work encompasses several major topics including DNA and nucleic acid chemistry, DNA repair mechanisms, advanced biosensing and bioanalysis techniques, RNA interference and gene delivery, genomics and chromatin dynamics, and cancer therapeutics and mechanisms.

Among recent publications attributed to Robert A. Bambara are:

  • G-quadruplex ligands targeting telomeres do not inhibit HIV promoter activity and cooperate with latency reversing agents in killing latently infected cells, 2020, published in Cell Cycle
  • DNA Polymerase Delta Exhibits Altered Catalytic Properties on Lysine Acetylation, 2023, published in Genes
  • Mechanism of Stimulation of Human DNA Ligase I by the Rad9-Rad1-Hus1 Checkpoint Complex, 2021, published in UNC Libraries
  • Long Patch Base Excision Repair Proceeds via Coordinated Stimulation of the Multienzyme DNA Repair Complex, 2020, published in UNC Libraries

Frequent co-authors collaborating with Bambara include:

  • Lata Balakrishnan (collaborated on 2 publications)
  • Laura A. Lindsey-Boltz (2 publications)
  • Aziz Sancar (2 publications)
  • Dorota Piekna-Przybylska (1 publication)
  • Sanjay B. Maggirwar (1 publication)

Most publications featuring Robert A. Bambara have appeared in the following venues:

  • UNC Libraries (2 publications)
  • Cell Cycle (1 publication)
  • Genes (1 publication)

The research contributions are centered on the mechanisms underlying DNA repair and nucleic acid chemistry, which includes examining enzymatic activities such as those of DNA polymerase and DNA ligase. Some work also involves exploring interactions relevant to cancer and viral latency, as well as advancing biosensing techniques for biochemical research applications.

Best Publications

  • Enzymes and Reactions at the Eukaryotic DNA Replication Fork

    Robert A. Bambara;Richard S. Murante;Leigh A. Henricksen

  • Flap Endonuclease 1: A Central Component of DNA Metabolism

    Yuan Liu;Hui-I Kao;Robert A. Bambara

  • DNA sequence analysis: a general, simple and rapid method for sequencing large oligodeoxyribonucleotide fragments by mapping

    Ernest Jay;Robert Bambara;R. Padmanabhan;Ray Wu

  • Macrophage Tropism of HIV-1 Depends on Efficient Cellular dNTP Utilization by Reverse Transcriptase

    Tracy L. Diamond;Mikhail Roshal;Varuni K. Jamburuthugoda;Holly M. Reynolds

  • Calf 5' to 3' exo/endonuclease must slide from a 5' end of the substrate to perform structure-specific cleavage.

    Richard S. Murante;Lynn Rust;Robert A. Bambara

  • Flap Endonuclease 1

    Lata Balakrishnan;Robert A. Bambara

  • Ataxia Telangiectasia Mutated (ATM) and ATM and Rad3-related Protein Exhibit Selective Target Specificities in Response to Different Forms of DNA Damage

    Christopher E. Helt;William A. Cliby;Peter C. Keng;Robert A. Bambara

  • Sequence Requirements for Estrogen Receptor Binding to Estrogen Response Elements

    Mark D. Driscoll;G. Sathya;Mesut Muyan;Carolyn M. Klinge

  • Enzymatic completion of mammalian lagging-strand DNA replication.

    John Turchi;Lin Huang;Richard S. Murante;Yong Kim;Yong Kim

  • Size classes of products synthesized processively by DNA polymerase III and DNA polymerase III holoenzyme of Escherichia coli.

    P J Fay;K O Johanson;C S McHenry;R A Bambara

  • Mechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1.

    Samson Tom;Leigh A. Henricksen;Robert A. Bambara

  • Single-Chain Estrogen Receptors (ERs) Reveal that the ERα/β Heterodimer Emulates Functions of the ERα Dimer in Genomic Estrogen Signaling Pathways

    Xiaodong Li;Jing Huang;Ping Yi;Robert A. Bambara

  • Polymerization and RNase H activities of the reverse transcriptases from avian myeloblastosis, human immunodeficiency, and Moloney murine leukemia viruses are functionally uncoupled.

    J J DeStefano;R G Buiser;L M Mallaber;T W Myers

  • The calf 5'- to 3'-exonuclease is also an endonuclease with both activities dependent on primers annealed upstream of the point of cleavage

    Richard S. Murante;Lin Huang;John J. Turchi;Robert A. Bambara

  • Cleavage specificity of Saccharomyces cerevisiae flap endonuclease 1 suggests a double-flap structure as the cellular substrate.

    Hui-I Kao;Leigh A. Henricksen;Yuan Liu;Robert A. Bambara

  • Purification and characterization of two new high molecular weight forms of DNA polymerase delta.

    James J. Crute;Alan F. Wahl;Robert A. Bambara

  • Requirement for proliferating cell nuclear antigen expression during stages of the Chinese hamster ovary cell cycle.

    Yin Chang Liu;Robert L. Marraccino;Peter C. Keng;Robert A. Bambara

  • Influence of human immunodeficiency virus nucleocapsid protein on synthesis and strand transfer by the reverse transcriptase in vitro.

    Lorna Rodrguez-Rodrguez;Zenta Tsuchihashi;Gloria M. Fuentes;Robert A. Bambara

  • Strand transfer events during HIV-1 reverse transcription

    Vandana Purohit Basu;Min Song;Lu Gao;Sean T. Rigby

  • Requirements for strand transfer between internal regions of heteropolymer templates by human immunodeficiency virus reverse transcriptase.

    J J DeStefano;L M Mallaber;L Rodriguez-Rodriguez;P J Fay

Frequent Co-Authors

Philip J. Fay
Philip J. Fay University of Rochester
Russell Hilf
Russell Hilf University of Rochester
Carolyn M. Klinge
Carolyn M. Klinge University of Louisville
Judith L. Campbell
Judith L. Campbell California Institute of Technology
Bernard P. Roques
Bernard P. Roques Université Paris Cité
Baek Kim
Baek Kim Emory University
Peter C. Keng
Peter C. Keng University of Rochester
Stephen Dewhurst
Stephen Dewhurst University of Rochester
Vicente Planelles
Vicente Planelles University of Utah
Ray Wu
Ray Wu Cornell University

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