D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 56 Citations 8,668 118 World Ranking 10136 National Ranking 4437

Research.com Recognitions

Awards & Achievements

1984 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • DNA
  • Gene
  • Enzyme

Charles S. McHenry mainly focuses on Molecular biology, DNA polymerase III holoenzyme, Polymerase, DNA polymerase and Biochemistry. He combines subjects such as Prokaryotic DNA replication, Replisome, Escherichia coli, Cell biology and Primase with his study of Molecular biology. His Polymerase study integrates concerns from other disciplines, such as DNA polymerase II and Protein subunit.

The study incorporates disciplines such as Okazaki fragments, RNA polymerase III and DNA clamp in addition to DNA polymerase II. His specific area of interest is DNA polymerase, where Charles S. McHenry studies Processivity. In general Biochemistry, his work in Gene and Binding site is often linked to Fluorodeoxyuridylate linking many areas of study.

His most cited work include:

  • Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate. (528 citations)
  • Coupling of a Replicative Polymerase and Helicase: A τ–DnaB Interaction Mediates Rapid Replication Fork Movement (311 citations)
  • The gamma subunit of DNA polymerase III holoenzyme of Escherichia coli is produced by ribosomal frameshifting. (205 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include DNA polymerase III holoenzyme, Molecular biology, DNA polymerase, Polymerase and Biochemistry. His study in Molecular biology is interdisciplinary in nature, drawing from both Nucleic acid sequence, Gene, Escherichia coli, Coding strand and Prokaryotic DNA replication. His DNA polymerase study combines topics in areas such as RNA polymerase III, Specificity factor, Binding site and DNA replication.

Charles S. McHenry has included themes like Okazaki fragments and Amino acid in his Polymerase study. His Exonuclease, ATP synthase alpha/beta subunits, Enzyme and Operon study in the realm of Biochemistry interacts with subjects such as Fluorescence spectrometry. His studies examine the connections between DNA clamp and genetics, as well as such issues in DNA polymerase II, with regards to DNA polymerase I and DNA polymerase mu.

He most often published in these fields:

  • DNA polymerase III holoenzyme (53.72%)
  • Molecular biology (52.89%)
  • DNA polymerase (51.24%)

What were the highlights of his more recent work (between 2006-2016)?

  • DNA replication (27.27%)
  • Polymerase (48.76%)
  • DNA polymerase (51.24%)

In recent papers he was focusing on the following fields of study:

DNA replication, Polymerase, DNA polymerase, Processivity and Molecular biology are his primary areas of study. His Polymerase study improves the overall literature in Biochemistry. DNA polymerase is a subfield of DNA that Charles S. McHenry investigates.

His biological study spans a wide range of topics, including dnaX, RNA polymerase III and DNA clamp. His research in DNA clamp intersects with topics in DNA polymerase delta and DNA polymerase II. The various areas that Charles S. McHenry examines in his Molecular biology study include Okazaki fragments and Thermophile.

Between 2006 and 2016, his most popular works were:

  • DNA Replicases from a Bacterial Perspective (120 citations)
  • Reconstitution of the B. subtilis Replisome with 13 Proteins Including Two Distinct Replicases (81 citations)
  • Multiple C-terminal tails within a single E. coli SSB homotetramer coordinate DNA replication and repair. (49 citations)

In his most recent research, the most cited papers focused on:

  • DNA
  • Gene
  • Enzyme

Charles S. McHenry spends much of his time researching DNA replication, DNA clamp, Processivity, DNA polymerase delta and DNA polymerase. His DNA replication research integrates issues from Binding domain and Cell biology. His research integrates issues of Molecular biology and DNA polymerase II in his study of DNA clamp.

His study looks at the relationship between DNA polymerase delta and topics such as Biophysics, which overlap with Transcription bubble and Coding strand. His study with DNA polymerase involves better knowledge in Biochemistry. Charles S. McHenry is interested in Polymerase, which is a field of Biochemistry.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate.

Daniel V. Santi;Charles S. McHenry;Hans Sommer.
Biochemistry (1974)

840 Citations

Coupling of a Replicative Polymerase and Helicase: A τ–DnaB Interaction Mediates Rapid Replication Fork Movement

Sungsub Kim;H.Garry Dallmann;Charles S McHenry;Kenneth J Marians;Kenneth J Marians.
Cell (1996)

410 Citations

The gamma subunit of DNA polymerase III holoenzyme of Escherichia coli is produced by ribosomal frameshifting.

Ann M. Flower;Charles S. McHenry.
Proceedings of the National Academy of Sciences of the United States of America (1990)

340 Citations

DNA polymerase III holoenzyme of Escherichia coli.

Charles S. McHenry.
Annual Review of Biochemistry (1988)

302 Citations

Human immunodeficiency virus nucleocapsid protein accelerates strand transfer of the terminally redundant sequences involved in reverse transcription.

Ji Chang You;C. S. Mchenry.
Journal of Biological Chemistry (1994)

267 Citations

Size classes of products synthesized processively by DNA polymerase III and DNA polymerase III holoenzyme of Escherichia coli.

P J Fay;K O Johanson;C S McHenry;R A Bambara.
Journal of Biological Chemistry (1981)

247 Citations

5-Fluoro-2'-deoxyuridylate: covalent complex with thymidylate synthetase.

Daniel V. Santi;Charles S. McHenry.
Proceedings of the National Academy of Sciences of the United States of America (1972)

219 Citations

The χψ Subunits of DNA Polymerase III Holoenzyme Bind to Single-stranded DNA-binding Protein (SSB) and Facilitate Replication of an SSB-coated Template

Bradley P. Glover;Charles S. McHenry.
Journal of Biological Chemistry (1998)

215 Citations

Chromosomal replicases as asymmetric dimers: studies of subunit arrangement and functional consequences

Charles S. McHenry.
Molecular Microbiology (2003)

196 Citations

DNA Replicases from a Bacterial Perspective

Charles S. McHenry.
Annual Review of Biochemistry (2011)

194 Citations

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