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Neuroscience

D-Index
36
Citations
5000
World Ranking
9028
National Ranking
3814

Overview

Grace C. Rossi is a researcher affiliated with Long Island University in the United States. Their work spans multiple intersecting fields including Biochemistry, Genetics and Molecular Biology, Neuroscience, and Medicine, with a focus on molecular and cellular mechanisms related to receptor signaling and pain management.

The scientist's research encompasses a range of specialized topics such as Neuropeptides and Animal Physiology, Receptor Mechanisms and Signaling, Pharmacological Receptor Mechanisms and Effects, Pain Mechanisms and Treatments, Alkaloids synthesis and pharmacology, Cancer Genomics and Diagnostics, and Glioma Diagnosis and Treatment.

Frequent coauthors collaborating with Grace C. Rossi include Ying-Xian Pan, Richard J. Bodnar, Balázs R. Varga, Rajendra Uprety, and Barnali Paul.

Research contributions have been published in several academic venues including:

  • Cellular and Molecular Neurobiology
  • ACS Chemical Neuroscience
  • Journal of Pharmacology and Experimental Therapeutics
  • Neuro-Oncology

Representative recent papers authored or coauthored by Grace C. Rossi include:

  • Interactive Mechanisms of Supraspinal Sites of Opioid Analgesic Action: A Festschrift to Dr. Gavril W. Pasternak, 2020, Cellular and Molecular Neurobiology
  • Synthesis and Pharmacology of a Morphinan-Derived Dual Mu-Kappa Opioid Receptor Agonist Analgesic, 2025, ACS Chemical Neuroscience
  • Targeting Exon 7-associated 7TM C-Terminal Variants of the Mu Opioid Receptor Gene for Mitigating Adverse Effects of Mu Opioids Without Altering Analgesia in Pain Management, 2024, Journal of Pharmacology and Experimental Therapeutics
  • METB-05. CSF LIQUID BIOPSY: PAVING THE WAY FOR MINIMALLY INVASIVE BRAIN TUMOR SURVEILLANCE USING LOW-PASS WHOLE GENOME SEQUENCING, 2024, Neuro-Oncology

Their research addresses biochemical and pharmacological aspects of opioid receptors and pain mechanisms, as well as advancing diagnostic techniques in brain tumor surveillance. Molecular biology and cellular neuroscience form the core methodological approaches in their investigations.

Grace C. Rossi's profile highlights an interdisciplinary engagement with complex biological systems, notably integrating pharmacology with genetic and molecular techniques to explore therapeutic mechanisms and diagnostic innovations.

Best Publications

  • Identification and Characterization of Three New Alternatively Spliced μ-Opioid Receptor Isoforms

    Ying-Xian Pan;Jin Xu;Elizabeth Bolan;Catherine Abbadie

  • Pharmacological characterization of Endomorphin-1 and Endomorphin-2 in Mouse Brain

    Ira E. Goldberg;Grace C. Rossi;Sharon R. Letchworth;John P. Mathis

  • Antisense mapping the MOR-1 opioid receptor: evidence for alternative splicing and a novel morphine-6β-glucuronide receptor

    Grace C. Rossi;Grace C. Rossi;Ying Xin Pan;Ying Xin Pan;George P. Brown;George P. Brown;Gavril W. Pasternak;Gavril W. Pasternak

  • Novel receptor mechanisms for heroin and morphine-6β-glucuronide analgesia☆

    Grace C. Rossi;George P. Brown;George P. Brown;Liza Leventhal;Liza Leventhal;Ke Yang;Ke Yang

  • Spinal analgesic activity of orphanin FQ/nociceptin and its fragments

    Michael A King;Grace C Rossi;Albert H Chang;LaShone Williams

  • Cloning and functional characterization through antisense mapping of a kappa 3-related opioid receptor.

    Ying-Xian Pan;Jie Cheng;Jin Xu;G. Rossi

  • Antisense mapping of MOR-1 in rats: distinguishing between morphine and morphine-6beta-glucuronide antinociception.

    Grace C. Rossi;Liza Leventhal;Ying-Xin Pan;Jessica Cole

  • Naloxone sensitive orphanin FQ-induced analgesia in mice

    Grace C. Rossi;Liza Leventhal;Gavril W. Pasternak

  • Differential blockade of opioid analgesia by antisense oligodeoxynucleotides directed against various G protein alpha subunits.

    K M Standifer;G C Rossi;G W Pasternak

  • Pharmacological Characterization of Orphanin FQ/Nociceptin and its Fragments

    Grace C. Rossi;Liza Leventhal;Elizabeth Bolan;Gavril W. Pasternak

  • μ and δ opioid synergy between the periaqueductal gray and the rostro-ventral medulla

    Grace C. Rossi;Gavril W. Pasternak;Gavril W. Pasternak;Richard J. Bodnar

  • Blockade of morphine analgesia by an antisense oligodeoxynucleotide against the mu receptor

    Grace Rossi;Ying-Xian Pan;Ying-Xian Pan;Jie Cheng;Jie Cheng;Gavril W. Pasternak;Gavril W. Pasternak

  • Isolation and expression of a novel alternatively spliced mu opioid receptor isoform, MOR-1F.

    Ying Xian Pan;Jin Xu;Elizabeth Bolan;Albert Chang

  • Differential blockade of morphine and morphine-6β-glucuronide analgesia by antisense oligodeoxynucleotides directed against MOR-1 and G-protein α subunits in rats

    Grace C. Rossi;Kelly M. Standifer;Gavril W. Pasternak;Gavril W. Pasternak

  • Medullary μ and δ opioid receptors modulate mesencephalic morphine analgesia in rats

    Jacquiline M. Kiefel;Grace C. Rossi;Richard J. Bodnar;Richard J. Bodnar

  • Involvement of exon 11-associated variants of the mu opioid receptor MOR-1 in heroin, but not morphine, actions

    Ying Xian Pan;Jin Xu;Mingming Xu;Grace C. Rossi

  • 3-Methoxynaltrexone, a selective heroin/morphine-6β-glucuronide antagonist

    George P Brown;Ke Yang;Michael A King;Grace C Rossi

  • Synergistic brainstem interactions for morphine analgesia.

    Grace C. Rossi;Gavril W. Pasternak;Gavril W. Pasternak;Richard J. Bodnar;Richard J. Bodnar

  • Dynorphin A1–17-Induced Feeding: Pharmacological Characterization Using Selective Opioid Antagonists and Antisense Probes in Rats

    Robert M. Silva;Henya C. Grossman;Maria M. Hadjimarkou;Grace C. Rossi

  • Mediation of opioid analgesia by a truncated 6-transmembrane GPCR

    Zhigang Lu;Jin Xu;Grace C. Rossi;Susruta Majumdar

Frequent Co-Authors

Gavril W. Pasternak
Gavril W. Pasternak Memorial Sloan Kettering Cancer Center
Richard J. Bodnar
Richard J. Bodnar Queens College, CUNY
John E. Pintar
John E. Pintar Rutgers, The State University of New Jersey
James E. Zadina
James E. Zadina Tulane University
Jeffrey S. Mogil
Jeffrey S. Mogil McGill University

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