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Peter W. Schiller

Peter W. Schiller

D-Index & Metrics

Chemistry

D-Index
61
Citations
13056
World Ranking
9260
National Ranking
238

Research.com Recognitions

  • 2001 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1991 - Fellow of the Royal Society of Canada Academy of Science

Overview

Peter W. Schiller is affiliated with the University of Montreal in Canada. Their research primarily focuses on the fields of biochemistry, genetics, and molecular biology, with a significant emphasis on molecular biology as a subfield. Additional areas of specialization include pharmaceutical science, physiology, cellular and molecular neuroscience, and cell biology.

The scientist's work encompasses several main topics, notably advanced drug delivery systems, lipid membrane structure and behavior, pain mechanisms and treatments, neuropeptides and animal physiology, biotin and related studies, computational drug discovery methods, and RNA interference and gene delivery.

Recent published papers include: Mannosylated glycoliposomes for the delivery of a peptide kappa opioid receptor antagonist to the brain (2020, European Journal of Pharmaceutics and Biopharmaceutics); Improving the Utility of a Dynorphin Peptide Analogue Using Mannosylated Glycoliposomes (2021, International Journal of Molecular Sciences); Protective effect of a mitochondria-targeting peptide against paclitaxel-induced peripheral neuropathy (2022, Chemical Biology & Drug Design); Novel µ opioid antagonists derived from the µ opioid agonists endomorphin and [Dmt¹]DALDA (H-Dmt-D-Arg-Phe-Lys-NH₂) (2020, Chemical Biology & Drug Design); and Inhaltsverzeichnis (2021, CITplus).

Frequent coauthors include Mathangi Ramesh, Michela I. Simone, Joseph Audie, Jürgen Bajorath, and María Laura Bolognesi.

The primary venues for publication are Chemical Biology & Drug Design, the European Journal of Pharmaceutics and Biopharmaceutics, the International Journal of Molecular Sciences, CITplus, and Peptide Science.

The scientist has been recognized with fellowships including Fellow of the Royal Society of Canada (1991, Academy of Science) and Fellow of the American Association for the Advancement of Science (AAAS) in 2001.

Best Publications

  • Cell-permeable Peptide Antioxidants Targeted to Inner Mitochondrial Membrane inhibit Mitochondrial Swelling, Oxidative Cell Death, and Reperfusion Injury

    Kesheng Zhao;Guo-Min Zhao;Dunli Wu;Yi Soong

  • Differential stereochemical requirements of mu vs. delta opioid receptors for ligand binding and signal transduction: development of a class of potent and highly delta-selective peptide antagonists.

    P. W. Schiller;T. M.-D. Nguyen;G. Weltrowska;B. C. Wilkes

  • A Genetically Encoded Biosensor Reveals Location Bias of Opioid Drug Action

    Miriam Carolin Stoeber;Damien Jullié;Braden T Lobingier;Toon Laeremans

  • Localization of immunoreactive synthetic atrial natriuretic factor (ANF) in the heart of various animal species.

    C Chapeau;J Gutkowska;P W Schiller;R W Milne

  • SYNTHESIS AND PHARMACOLOGICAL CHARACTERIZATION IN VITRO OF CYCLIC ENKEPHALIN ANALOGS: EFFECT OF CONFORMATIONAL CONSTRAINTS ON OPIATE RECEPTOR SELECTIVITY

    J. Dimaio;T. M.-D. Nguyen;C. Lemieux;P. W. Schiller

  • MicroRNA-195 promotes palmitate-induced apoptosis in cardiomyocytes by down-regulating Sirt1

    Huaqing Zhu;Yixin Yang;Yixin Yang;Yanpeng Wang;Yanpeng Wang;Yanpeng Wang;Jianmin Li

  • An all D-amino acid opioid peptide with central analgesic activity from a combinatorial library

    CT Dooley;NN Chung;BC Wilkes;PW Schiller

  • The Opioid μ Agonist/δ Antagonist DIPP-NH2[Ψ] Produces a Potent Analgesic Effect, No Physical Dependence, and Less Tolerance than Morphine in Rats

    Peter W. Schiller;Marian E. Fundytus;Lisa Merovitz;Grazyna Weltrowska

  • Characterization of specific receptors for atrial natriuretic factor in bovine adrenal zona glomerulosa.

    A. De Léan;J. Gutkowska;N. McNicoll;P.W. Schiller

  • Bi- or multifunctional opioid peptide drugs.

    Peter W. Schiller

  • Structural basis for bifunctional peptide recognition at human δ-opioid receptor

    Gustavo Fenalti;Gustavo Fenalti;Nadia A. Zatsepin;Cecilia Betti;Patrick T. Giguere

  • Transcellular Transport of a Highly Polar 3+ Net Charge Opioid Tetrapeptide

    Kesheng Zhao;Guoxiong Luo;Guo-Min Zhao;Peter W. Schiller

  • Synthesis and in vitro opioid activity profiles of DALDA analogues

    Peter W Schiller;Thi M.-D Nguyen;Irena Berezowska;Sébastien Dupuis

  • Novel Therapies Targeting Inner Mitochondrial Membrane—From Discovery to Clinical Development

    Hazel H. Szeto;Peter W. Schiller

  • A cyclic enkephalin analog with high in vitro opiate activity.

    John Dimaio;Peter W. Schiller

  • Attenuation of morphine tolerance and dependence with the highly selective δ-opioid receptor antagonist TIPP[ψ]

    Marian E. Fundytus;Peter W. Schiller;Michelle Shapiro;Grazyna Weltrowska

  • TIPP[psi]: a highly potent and stable pseudopeptide delta opioid receptor antagonist with extraordinary delta selectivity.

    Peter W. Schiller;Grazyna Weltrowska;Thi M. D. Nguyen;Brian C. Wilkes

  • Bioluminescence Resonance Energy Transfer Assays Reveal Ligand-specific Conformational Changes within Preformed Signaling Complexes Containing δ-Opioid Receptors and Heterotrimeric G Proteins

    Nicolas Audet;Céline Galés;Élodie Archer-Lahlou;Marc Vallières

  • Unsulfated C-terminal 7-peptide of cholecystokinin: A new ligand of the opiate receptor

    Peter W. Schiller;Anthony Lipton;David F. Horrobin;Miklos Bodanszky

  • Conformational restriction of the phenylalanine residue in a cyclic opioid peptide analogue: effects on receptor selectivity and stereospecificity.

    P. W. Schiller;G. Weltrowska;T. M.-D. Nguyen;C. Lemieux

Frequent Co-Authors

Dirk Tourwé
Dirk Tourwé Vrije Universiteit Brussel
Hazel H. Szeto
Hazel H. Szeto Cornell University
Tony L. Yaksh
Tony L. Yaksh University of California, San Diego
Murray Goodman
Murray Goodman University of California, San Diego
Kim Q. Do
Kim Q. Do University of Lausanne
Yixin Lu
Yixin Lu National University of Singapore
Frank Porreca
Frank Porreca University of Arizona
Géza Tóth
Géza Tóth University of the Basque Country
Jolanta Gutkowska
Jolanta Gutkowska University of Montreal

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