D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 107 Citations 36,652 338 World Ranking 2720 National Ranking 1573

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Opioid

His main research concerns Pharmacology, Morphine, Receptor, Opioid and Analgesic. His Pharmacology research incorporates elements of Mechanism of action and Agonist, -Naloxone, μ-opioid receptor, Antagonist. His Morphine research is multidisciplinary, incorporating perspectives in NMDA receptor, Endocrinology, Drug tolerance and Enkephalin.

Gavril W. Pasternak interconnects Molecular biology and Alternative splicing, Exon in the investigation of issues within Receptor. His work deals with themes such as Anesthesia, Periaqueductal gray and Intensive care medicine, which intersect with Opioid. His Analgesic study incorporates themes from Central nervous system, Nortriptyline, Respiratory system, Reserpine and Spinal cord.

His most cited work include:

  • Clinical Guidelines for the Use of Chronic Opioid Therapy in Chronic Noncancer Pain (1675 citations)
  • Pharmacological mechanisms of opioid analgesics. (504 citations)
  • Strategies to Manage the Adverse Effects of Oral Morphine: An Evidence-Based Report (479 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Pharmacology, Receptor, Opioid, Morphine and Opioid receptor. He specializes in Pharmacology, namely Analgesic. His Receptor research incorporates themes from Molecular biology, Stereochemistry, Binding site and Mechanism of action.

The Opioid study combines topics in areas such as Agonist, Anesthesia and Endocrinology. His Morphine research integrates issues from Nociception, NMDA receptor, Enkephalin, Periaqueductal gray and Potency. His Opioid receptor study combines topics from a wide range of disciplines, such as Nociceptin receptor, Clone, Neuroscience and Naltrexone.

He most often published in these fields:

  • Pharmacology (72.31%)
  • Receptor (53.93%)
  • Opioid (50.83%)

What were the highlights of his more recent work (between 2012-2021)?

  • Pharmacology (72.31%)
  • Opioid (50.83%)
  • Receptor (53.93%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Pharmacology, Opioid, Receptor, μ-opioid receptor and Alternative splicing. Gavril W. Pasternak is interested in Morphine, which is a branch of Pharmacology. His Morphine study integrates concerns from other disciplines, such as In vivo, -Naloxone and Bioinformatics.

His work investigates the relationship between Opioid and topics such as Analgesic that intersect with problems in Physical dependence and Chronic pain. He usually deals with μ-opioid receptor and limits it to topics linked to Buprenorphine and Nociceptin receptor. His Alternative splicing research is multidisciplinary, incorporating elements of Molecular biology, RNA splicing and splice.

Between 2012 and 2021, his most popular works were:

  • Mu Opioids and Their Receptors: Evolution of a Concept (271 citations)
  • The Opiate Receptors (164 citations)
  • Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor (148 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

Gavril W. Pasternak mainly investigates Pharmacology, Opioid, Receptor, μ-opioid receptor and Alternative splicing. The various areas that Gavril W. Pasternak examines in his Pharmacology study include IBNtxA, δ-opioid receptor and Opiate. His Opioid study combines topics in areas such as Morphine, Analgesic and Dosing.

His work carried out in the field of Analgesic brings together such families of science as Chronic pain and Heroin. His work in G protein-coupled receptor and Opioid receptor is related to Receptor. His μ-opioid receptor research includes elements of Nociceptin receptor, Buprenorphine, Drug tolerance, Opioid analgesics and Functional selectivity.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Clinical Guidelines for the Use of Chronic Opioid Therapy in Chronic Noncancer Pain

Roger Chou;Gilbert J. Fanciullo;Perry G. Fine;Jeremy A. Adler.
The Journal of Pain (2009)

2406 Citations

Strategies to Manage the Adverse Effects of Oral Morphine: An Evidence-Based Report

Nathan Cherny;Carla Ripamonti;Jose Pereira;Carol Davis.
Journal of Clinical Oncology (2001)

746 Citations

Pharmacological mechanisms of opioid analgesics.

Gavril W. Pasternak.
Clinical Neuropharmacology (1993)

724 Citations

Opiate Agonists and Antagonists Discriminated by Receptor Binding in Brain

Candace B. Pert;Gavril Pasternak;Solomon H. Snyder.
Science (1973)

641 Citations

The Molecular and Behavioral Pharmacology of the Orphanin FQ/Nociceptin Peptide and Receptor Family

Jeffrey S. Mogil;Gavril W. Pasternak.
Pharmacological Reviews (2001)

513 Citations

Retention of Supraspinal Delta-like Analgesia and Loss of Morphine Tolerance in δ Opioid Receptor Knockout Mice

Yanxin Zhu;Michael A. King;Alwin G.P. Schuller;Joshua F. Nitsche.
Neuron (1999)

491 Citations

An endogenous morphine-like factor in mammalian brain.

Gavril W. Pasternak;Robert Goodman;Solomon H. Snyder.
Life Sciences (1975)

490 Citations

Minireview: Multiple MU opiate receptors

Gavril W. Pasternak;Paul J. Wood.
Life Sciences (1986)

486 Citations

Classification of multiple morphine and enkephalin binding sites in the central nervous system

Benjamen L. Wolozin;Gavril W. Pasternak.
Proceedings of the National Academy of Sciences of the United States of America (1981)

486 Citations

Pharmacological characterization of morphine-6 beta-glucuronide, a very potent morphine metabolite.

D Paul;K M Standifer;C E Inturrisi;G W Pasternak.
Journal of Pharmacology and Experimental Therapeutics (1989)

456 Citations

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