His main research concerns Pharmacology, Morphine, Receptor, Opioid and Analgesic. His Pharmacology research incorporates elements of Mechanism of action and Agonist, -Naloxone, μ-opioid receptor, Antagonist. His Morphine research is multidisciplinary, incorporating perspectives in NMDA receptor, Endocrinology, Drug tolerance and Enkephalin.
Gavril W. Pasternak interconnects Molecular biology and Alternative splicing, Exon in the investigation of issues within Receptor. His work deals with themes such as Anesthesia, Periaqueductal gray and Intensive care medicine, which intersect with Opioid. His Analgesic study incorporates themes from Central nervous system, Nortriptyline, Respiratory system, Reserpine and Spinal cord.
His primary scientific interests are in Pharmacology, Receptor, Opioid, Morphine and Opioid receptor. He specializes in Pharmacology, namely Analgesic. His Receptor research incorporates themes from Molecular biology, Stereochemistry, Binding site and Mechanism of action.
The Opioid study combines topics in areas such as Agonist, Anesthesia and Endocrinology. His Morphine research integrates issues from Nociception, NMDA receptor, Enkephalin, Periaqueductal gray and Potency. His Opioid receptor study combines topics from a wide range of disciplines, such as Nociceptin receptor, Clone, Neuroscience and Naltrexone.
His primary areas of investigation include Pharmacology, Opioid, Receptor, μ-opioid receptor and Alternative splicing. Gavril W. Pasternak is interested in Morphine, which is a branch of Pharmacology. His Morphine study integrates concerns from other disciplines, such as In vivo, -Naloxone and Bioinformatics.
His work investigates the relationship between Opioid and topics such as Analgesic that intersect with problems in Physical dependence and Chronic pain. He usually deals with μ-opioid receptor and limits it to topics linked to Buprenorphine and Nociceptin receptor. His Alternative splicing research is multidisciplinary, incorporating elements of Molecular biology, RNA splicing and splice.
Gavril W. Pasternak mainly investigates Pharmacology, Opioid, Receptor, μ-opioid receptor and Alternative splicing. The various areas that Gavril W. Pasternak examines in his Pharmacology study include IBNtxA, δ-opioid receptor and Opiate. His Opioid study combines topics in areas such as Morphine, Analgesic and Dosing.
His work carried out in the field of Analgesic brings together such families of science as Chronic pain and Heroin. His work in G protein-coupled receptor and Opioid receptor is related to Receptor. His μ-opioid receptor research includes elements of Nociceptin receptor, Buprenorphine, Drug tolerance, Opioid analgesics and Functional selectivity.
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Clinical Guidelines for the Use of Chronic Opioid Therapy in Chronic Noncancer Pain
Roger Chou;Gilbert J. Fanciullo;Perry G. Fine;Jeremy A. Adler.
The Journal of Pain (2009)
Strategies to Manage the Adverse Effects of Oral Morphine: An Evidence-Based Report
Nathan Cherny;Carla Ripamonti;Jose Pereira;Carol Davis.
Journal of Clinical Oncology (2001)
Pharmacological mechanisms of opioid analgesics.
Gavril W. Pasternak.
Clinical Neuropharmacology (1993)
Opiate Agonists and Antagonists Discriminated by Receptor Binding in Brain
Candace B. Pert;Gavril Pasternak;Solomon H. Snyder.
The Molecular and Behavioral Pharmacology of the Orphanin FQ/Nociceptin Peptide and Receptor Family
Jeffrey S. Mogil;Gavril W. Pasternak.
Pharmacological Reviews (2001)
Retention of Supraspinal Delta-like Analgesia and Loss of Morphine Tolerance in δ Opioid Receptor Knockout Mice
Yanxin Zhu;Michael A. King;Alwin G.P. Schuller;Joshua F. Nitsche.
An endogenous morphine-like factor in mammalian brain.
Gavril W. Pasternak;Robert Goodman;Solomon H. Snyder.
Life Sciences (1975)
Minireview: Multiple MU opiate receptors
Gavril W. Pasternak;Paul J. Wood.
Life Sciences (1986)
Classification of multiple morphine and enkephalin binding sites in the central nervous system
Benjamen L. Wolozin;Gavril W. Pasternak.
Proceedings of the National Academy of Sciences of the United States of America (1981)
Pharmacological characterization of morphine-6 beta-glucuronide, a very potent morphine metabolite.
D Paul;K M Standifer;C E Inturrisi;G W Pasternak.
Journal of Pharmacology and Experimental Therapeutics (1989)
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