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Molecular Biology

D-Index
73
Citations
15005
World Ranking
1294
National Ranking
665

Research.com Recognitions

  • 2015 - Fellow of the American Academy of Arts and Sciences
  • 2006 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Kenneth J. Marians is affiliated with Memorial Sloan Kettering Cancer Center in the United States. Their research primarily centers on the fields of Biochemistry, Genetics, and Molecular Biology, with significant contributions in Molecular Biology and Genetics. The scientist's work also touches on Plant Science and Molecular Medicine.

The main research topics covered in Kenneth J. Marians' publications include DNA Repair Mechanisms, Bacterial Genetics and Biotechnology, DNA and Nucleic Acid Chemistry, Cancer therapeutics and mechanisms, Advanced biosensing and bioanalysis techniques, RNA and protein synthesis mechanisms, and Chromosomal and Genetic Variations.

Frequent co-authors collaborating with Kenneth J. Marians are Soon Bahng, Jan-Gert Brüning, Rupesh Kumar, Sahil Batra, and Benjamin Allwein.

The scientist has published works in several journals, with key publication venues being:

  • Nucleic Acids Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biological Chemistry
  • Science
  • Proceedings of the National Academy of Sciences

Among recent papers, those authored or co-authored by Kenneth J. Marians include:

  • Replisome bypass of transcription complexes and R-loops, 2020, Nucleic Acids Research
  • Bypass of complex co-directional replication-transcription collisions by replisome skipping, 2021, Nucleic Acids Research
  • The MukB-topoisomerase IV interaction mutually suppresses their catalytic activities, 2021, Nucleic Acids Research
  • Two components of DNA replication-dependent LexA cleavage, 2020, Journal of Biological Chemistry
  • G-quadruplex-stalled eukaryotic replisome structure reveals helical inchworm DNA translocation, 2025, Science

Kenneth J. Marians has been recognized by peers through election as a Fellow of the American Academy of Arts and Sciences in 2015 and as a Fellow of the American Association for the Advancement of Science (AAAS) in 2006.

Best Publications

  • The importance of repairing stalled replication forks

    Michael M. Cox;Myron F. Goodman;Kenneth N. Kreuzer;David J. Sherratt

  • Replisome assembly and the direct restart of stalled replication forks.

    Ryan C Heller;Kenneth J Marians

  • Escherichia coli topoisomerase IV : purification, characterization, subunit structure, and subunit interactions

    Hong Peng;K. J. Marians

  • Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. I. Multiple effectors act to modulate Okazaki fragment size.

    C A Wu;E L Zechner;K J Marians

  • Identification of a potent decatenating enzyme from Escherichia coli.

    R J DiGate;K J Marians

  • Role of PriA in replication fork reactivation in Escherichia coli.

    Steven J. Sandler;Kenneth J. Marians

  • Rescuing Stalled or Damaged Replication Forks

    Joseph T.P. Yeeles;Jérôme Poli;Kenneth J. Marians;Philippe Pasero

  • The DNA replication protein PriA and the recombination protein RecG bind D-loops

    Peter McGlynn;Abdulwahab A Al-Deib;Joing Liu;Kenneth J Marians

  • Inactivation of the Escherichia coli priA DNA replication protein induces the SOS response.

    P Nurse;K H Zavitz;K J Marians

  • The Escherichia coli preprimosome and DNA B helicase can form replication forks that move at the same rate.

    M Mok;KJ Marians

  • Identification of a domain of Escherichia coli primase required for functional interaction with the DnaB helicase at the replication fork.

    K. Tougu;Hong Peng;K. J. Marians

  • The structure of supercoiled intermediates in DNA replication.

    Brian J Peter;Chris Ullsperger;Hiroshi Hiasa;Kenneth J Marians

  • Formation of Holliday junctions by regression of nascent DNA in intermediates containing stalled replication forks: RecG stimulates regression even when the DNA is negatively supercoiled

    Peter McGlynn;Robert G. Lloyd;Kenneth J. Marians

  • Decatenation activity of topoisomerase IV during oriC and pBR322 DNA replication in vitro.

    Hong Peng;Kenneth J. Marians

  • ATPase-deficient mutants of the Escherichia coli DNA replication protein PriA are capable of catalyzing the assembly of active primosomes.

    K H Zavitz;K J Marians

  • The Escherichia coli Replisome Is Inherently DNA Damage Tolerant

    Joseph T. P. Yeeles;Kenneth J. Marians

  • Lesion Bypass and the Reactivation of Stalled Replication Forks

    Kenneth J. Marians

  • Resolution of Converging Replication Forks by RecQ and Topoisomerase III

    Catherine Suski;Kenneth J. Marians

  • Decatenating activity of Escherichia coli DNA gyrase and topoisomerases I and III during oriC and pBR322 DNA replication in vitro.

    Hiroshi Hiasa;Russell J. DiGate;Kenneth J. Marians

  • Molecular cloning and DNA sequence analysis of Escherichia coli topB, the gene encoding topoisomerase III.

    R J DiGate;K J Marians

Frequent Co-Authors

Steven J. Sandler
Steven J. Sandler University of Massachusetts Amherst
Robert G. Lloyd
Robert G. Lloyd University of Nottingham
Myron F. Goodman
Myron F. Goodman University of Southern California
Kenneth N. Kreuzer
Kenneth N. Kreuzer Duke University
Michael M. Cox
Michael M. Cox University of Wisconsin–Madison
David J. Sherratt
David J. Sherratt University of Oxford
Claire Wyman
Claire Wyman Erasmus MC
Alvin J. Clark
Alvin J. Clark University of Arizona
Hediye Erdjument-Bromage
Hediye Erdjument-Bromage New York University
Stephen C. Kowalczykowski
Stephen C. Kowalczykowski University of California, Davis

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