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Valakunja Nagaraja

Valakunja Nagaraja

D-Index & Metrics

Biology and Biochemistry

D-Index
42
Citations
7473
World Ranking
19473
National Ranking
97

Research.com Recognitions

  • 2012 - Fellow, The World Academy of Sciences

Overview

Valakunja Nagaraja is a researcher affiliated with the Indian Institute of Science in India. Their academic efforts are primarily situated within the fields of Biochemistry, Genetics and Molecular Biology, alongside Medicine. The research focuses notably on Molecular Biology, Molecular Medicine, Infectious Diseases, Epidemiology, and Genetics.

The central themes of their work encompass Antibiotic Resistance in Bacteria, Tuberculosis Research and Epidemiology, Epigenetics and DNA Methylation, Bacterial Genetics and Biotechnology, RNA modifications and cancer, Mycobacterium research and diagnosis, and RNA and protein synthesis mechanisms.

Key recent publications by Valakunja Nagaraja include:

  • Mycobacterium tuberculosis SufR responds to nitric oxide via its 4Fe-4S cluster and regulates Fe-S cluster biogenesis for persistence in mice (2021, Redox Biology)
  • Mycobacterium tuberculosis Calcium Pump CtpF Modulates the Autophagosome in an mTOR-Dependent Manner (2020, Frontiers in Cellular and Infection Microbiology)
  • Rv0802c is an acyltransferase that succinylates and acetylates Mycobacterium tuberculosis nucleoid-associated protein HU (2021, Microbiology)
  • The Mycobacterium tuberculosis methyltransferase Rv2067c manipulates host epigenetic programming to promote its own survival (2023, Nature Communications)
  • Intrinsic and Rho-dependent termination cooperate for efficient transcription termination at 3' untranslated regions (2022, Biochemical and Biophysical Research Communications)

The frequent co-authors collaborating with Nagaraja reflect ongoing research partnerships, and include:

  • Prakruti R. Singh
  • Arun Sai Kumar Peketi
  • Eswarappa Pradeep Bulagonda
  • Rajeev Jha
  • Shubha Udupa

Publication venues where Nagaraja has frequently contributed include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • Journal of Global Antimicrobial Resistance
  • Redox Biology
  • Microbiology

Nagaraja has been recognized as a Fellow of The World Academy of Sciences since 2012.

Best Publications

  • A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes

    Richard J. Roberts;Marlene Belfort;Timothy Bestor;Ashok S. Bhagwat

  • Diverse Functions of Restriction-Modification Systems in Addition to Cellular Defense

    Kommireddy Vasu;Valakunja Nagaraja;Valakunja Nagaraja

  • Synthesis and antimycobacterial evaluation of various 7-substituted ciprofloxacin derivatives

    Dharmarajan Sriram;Perumal Yogeeswari;Jafar Sadik Basha;Deshpande R. Radha

  • High levels of catalytic antibodies correlate with favorable outcome in sepsis.

    Sébastien Lacroix-Desmazes;Jagadeesh Bayry;Srini V. Kaveri;David Hayon-Sonsino

  • WebGeSTer DB—a transcription terminator database

    Anirban Mitra;Anil K. Kesarwani;Debnath Pal;Valakunja Nagaraja

  • Conserved economics of transcription termination in eubacteria

    Shyam Unniraman;Ranjana Prakash;Valakunja Nagaraja

  • Targeting Mycobacterium tuberculosis nucleoid-associated protein HU with structure-based inhibitors

    Tuhin Bhowmick;Soumitra Ghosh;Karuna Dixit;Varsha Ganesan

  • Alternate paradigm for intrinsic transcription termination in eubacteria.

    Shyam Unniraman;Ranjana Prakash;Valakunja Nagaraja;Valakunja Nagaraja

  • DNA topoisomerase I and DNA gyrase as targets for TB therapy.

    Valakunja Nagaraja;Adwait A. Godbole;Sara R. Henderson;Anthony Maxwell

  • Functional characterisation of mycobacterial DNA gyrase: an efficient decatenase

    U. H. Manjunatha;M. Dalal;M. Chatterji;D. R. Radha

  • Lysine acetylation of the Mycobacterium tuberculosis HU protein modulates its DNA binding and genome organization

    Soumitra Ghosh;Bhavna Padmanabhan;Chinmay Anand;Valakunja Nagaraja;Valakunja Nagaraja

  • Type II restriction endonuclease R.KpnI is a member of the HNH nuclease superfamily

    Matheshwaran Saravanan;Janusz M. Bujnicki;Iwona A. Cymerman;Desirazu Narasimha Rao

  • DNA Gyrase Genes in Mycobacterium tuberculosis: a Single Operon Driven by Multiple Promoters

    Shyam Unniraman;Monalisa Chatterji;Valakunja Nagaraja;Valakunja Nagaraja

  • Curcumin reduces the antimicrobial activity of ciprofloxacin against Salmonella Typhimurium and Salmonella Typhi

    Sandhya A. Marathe;Rupesh Kumar;Parthasarathi Ajitkumar;Valakunja Nagaraja

  • Synthesis and antimycobacterial activities of novel 6-nitroquinolone-3-carboxylic acids

    Palaniappan Senthilkumar;Murugesan Dinakaran;Perumal Yogeeswari;Dharmarajan Sriram

  • DNA translocation blockage, a general mechanism of cleavage site selection by type I restriction enzymes.

    Pavel Janscak;Maria P. MacWilliams;Ursula Sandmeier;Valakunja Nagaraja

  • A hybrid recognition sequence in a recombinant restriction enzyme and the evolution of DNA sequence specificity.

    Valakunja Nagaraja;John C. W. Shepherd;Thomas A. Bickle

  • Novel ofloxacin derivatives: synthesis, antimycobacterial and toxicological evaluation.

    Murugesan Dinakaran;Palaniappan Senthilkumar;Perumal Yogeeswari;Arnab China

  • HupB, a Nucleoid-Associated Protein of Mycobacterium tuberculosis, Is Modified by Serine/Threonine Protein Kinases In Vivo

    Meetu Gupta;Andaleeb Sajid;Kirti Sharma;Soumitra Ghosh

  • A nomenclature for restriction enzymes, DNA methyl transferases, homing endonucleases and their genes

    RJ Roberts;M Belford;T Bester;AS Bhagwat

Frequent Co-Authors

Perumal Yogeeswari
Perumal Yogeeswari Birla Institute of Technology and Science, Pilani
Dharmarajan Sriram
Dharmarajan Sriram Birla Institute of Technology and Science, Pilani
Thomas A. Bickle
Thomas A. Bickle University of Basel
Sébastien Lacroix-Desmazes
Sébastien Lacroix-Desmazes Sorbonne University
Sean Ekins
Sean Ekins University of Arizona
Anthony Maxwell
Anthony Maxwell John Innes Centre
Bhaskar D. Kulkarni
Bhaskar D. Kulkarni Council of Scientific and Industrial Research
Michel D. Kazatchkine
Michel D. Kazatchkine Université Paris Cité
Stewart T. Cole
Stewart T. Cole Institut Pasteur

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