World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
27086
World Ranking
3295
National Ranking
1669

Chemistry

D-Index
79
Citations
24008
World Ranking
3581
National Ranking
1158

Daniel V. Santi publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Daniel V. Santi sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 387 publications — 89th percentile

89% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Daniel V. Santi D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Daniel V. Santi sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 84 D-Index — 84th percentile

84% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Daniel V. Santi is affiliated with the University of California, San Francisco in the United States. Their research primarily spans the fields of medicine as well as biochemistry, genetics, and molecular biology. Their work concentrates on several subfields, including molecular biology, oncology, immunology, biomedical engineering, and biomaterials.

Their publication record includes papers focused on cancer therapeutics, drug delivery systems, immunotherapy, and DNA repair mechanisms. Recent papers include:

  • Does sacituzumab-govitecan act as a conventional antibody drug conjugate (ADC), a prodrug of SN-38 or both?, 2021, Annals of Translational Medicine

Daniel V. Santi has collaborated frequently with other researchers with whom they have coauthored multiple publications. Some of their most frequent collaborators are Gary W. Ashley, John A. Hangasky, Shaun D. Fontaine, Eric L. Schneider, and Niranjan Meher.

The scientist's work appears regularly in several journals where they have contributed multiple publications. The top venues featuring their research include:

  • Cancer Research
  • Engineering Reports
  • Frontiers in Immunology
  • Molecular Cancer Therapeutics
  • Bioconjugate Chemistry

Daniel V. Santi's research topics cover a range of areas with a focus on therapeutic approaches and mechanisms in oncology and immunology. These topics include:

  • Cancer therapeutics and mechanisms
  • Nanoparticle-Based Drug Delivery
  • CAR-T cell therapy research
  • PARP inhibition in cancer therapy
  • DNA Repair Mechanisms
  • Immune Cell Function and Interaction
  • Nanoplatforms for cancer theranostics

Their work in the biomedical engineering and biomaterials subfields has supported investigations into improved drug delivery systems and novel therapeutic platforms. The focus on molecular biology and oncology topics indicates an interdisciplinary approach toward understanding cancer biology and treatment strategies.

Best Publications

  • Peptoids: a modular approach to drug discovery.

    R J Simon;R S Kania;R N Zuckermann;V D Huebner

  • The Catalytic Mechanism and Structure of Thymidylate Synthase

    Christopher W. Carreras;Daniel V. Santi

  • Ribosomal RNA sequence shows Pneumocystis carinii to be a member of the Fungi

    Jeffrey C. Edman;Joseph A. Kovacs;Henry Masur;Daniel V. Santi

  • Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate.

    Daniel V. Santi;Charles S. McHenry;Hans Sommer

  • Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosine

    Daniel V. Santi;Anne Norment;Charles E. Garrett

  • On the mechanism of inhibition of DNA-cytosine methyltransferases by cytosine analogs.

    Daniel V. Santi;Charles E. Garrett;Philip J. Barr

  • Kinetic and catalytic mechanism of HhaI methyltransferase.

    John C. Wu;Daniel V. Santi

  • Long-term stabilization of maleimide-thiol conjugates.

    Shaun D. Fontaine;Ralph Reid;Louise Robinson;Gary W. Ashley

  • Hydrogel drug delivery system with predictable and tunable drug release and degradation rates

    Gary W. Ashley;Jeff Henise;Ralph Reid;Daniel V. Santi

  • A Model of Structure and Catalysis for Ketoreductase Domains in Modular Polyketide Synthases

    Ralph Reid;Misty Piagentini;Eduardo Rodriguez;Gary Ashley

  • Structure-based discovery of inhibitors of thymidylate synthase

    Brian K. Shoichet;Robert M. Stroud;Daniel V. Santi;Irwin D. Kuntz

  • ANTIFOLATE-RESISTANT MUTANTS OF PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE

    Worachart Sirawaraporn;Tanajit Sathitkul;Rachada Sirawaraporn;Yongyuth Yuthavong

  • Atomic structure of thymidylate synthase: target for rational drug design

    Larry W. Hardy;Janet S. Finer-Moore;William R. Montfort;Melvin O. Jones

  • Combinatorial polyketide biosynthesis by de novo design and rearrangement of modular polyketide synthase genes

    Hugo G Menzella;Ralph Reid;John R Carney;Sunil S Chandran

  • A rapid and sensitive high pressure liquid chromatography assay for deoxyribonucleoside triphosphates in cell extracts.

    Charles Garrett;Daniel V. Santi

  • Production of a polyketide natural product in nonpolyketide-producing prokaryotic and eukaryotic hosts

    James T. Kealey;Lu Liu;Daniel V. Santi;Mary C. Betlach

  • Total synthesis of long DNA sequences: Synthesis of a contiguous 32-kb polyketide synthase gene cluster

    Sarah J. Kodumal;Kedar G. Patel;Ralph Reid;Hugo G. Menzella

  • Unstable DNA amplifications in methotrexate-resistant Leishmania consist of extrachromosomal circles which relocalize during stabilization.

    Stephen M. Beverley;Jeffrey A. Coderre;Daniel V. Santi;Robert T. Schimke

  • Overproduction of a bifunctional thymidylate synthetase-dihydrofolate reductase and DNA amplification in methotrexate-resistant Leishmania tropica.

    Jeffrey A. Coderre;Stephen M. Beverley;Robert T. Schimke;Daniel V. Santi

  • Synthesis of methyl halides from biomass using engineered microbes.

    Travis S. Bayer;Daniel M. Widmaier;Karsten Temme;Ethan A. Mirsky

Frequent Co-Authors

Robert M. Stroud
Robert M. Stroud University of California, San Francisco
Chaitan Khosla
Chaitan Khosla Stanford University
Philip J. Barr
Philip J. Barr BayMedica, Inc.
Padmanabhan Balaram
Padmanabhan Balaram Indian Institute of Science
Akira Matsuda
Akira Matsuda Juntendo University
Peter V. Danenberg
Peter V. Danenberg University of Southern California
Ronald N. Zuckermann
Ronald N. Zuckermann Lawrence Berkeley National Laboratory
Irwin D. Kuntz
Irwin D. Kuntz University of California, San Francisco
Brian K. Shoichet
Brian K. Shoichet University of California, San Francisco
Leonard Katz
Leonard Katz Haskins Laboratories

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