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Microbiology

D-Index
57
Citations
7910
World Ranking
3646
National Ranking
1430

Overview

Melanie T. Cushion is affiliated with the University of Cincinnati Medical Center in the United States. Their research primarily focuses on medical fields, with significant expertise in epidemiology and infectious diseases, as well as contributions to organic chemistry, immunology, and molecular biology.

The scientist's work extensively addresses topics related to Pneumocystis jirovecii pneumonia detection and treatment, antifungal resistance and susceptibility, tuberculosis research and epidemiology, fungal infections and studies, synthesis and biological evaluation, pneumonia and respiratory infections, and HIV/AIDS drug development and treatment.

Frequent coauthors collaborating with Melanie T. Cushion include Alan Ashbaugh, Steven G. Sayson, Joseph A. Kovacs, Aleksey Porollo, and Ousmane H. Cissé.

Their publications appear often in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Antimicrobial Agents and Chemotherapy
  • mBio
  • Microbiology Spectrum
  • Frontiers in Microbiology

Selected recent papers authored or coauthored by Melanie T. Cushion include:

  • The Persistent Challenge of Pneumocystis Growth Outside the Mammalian Lung: Past and Future Approaches, 2021, Frontiers in Microbiology
  • The Long-Acting Echinocandin, Rezafungin, Prevents Pneumocystis Pneumonia and Eliminates Pneumocystis from the Lungs in Prophylaxis and Murine Treatment Models, 2021, Journal of Fungi
  • Efficacy of Rezafungin in Prophylactic Mouse Models of Invasive Candidiasis, Aspergillosis, and Pneumocystis Pneumonia, 2020, Antimicrobial Agents and Chemotherapy
  • Genomic insights into the host specific adaptation of the Pneumocystis genus, 2021, Communications Biology
  • Diversity and Complexity of the Large Surface Protein Family in the Compacted Genomes of Multiple Pneumocystis Species, 2020, mBio

Best Publications

  • Pneumocystis carinii: sequence from ribosomal RNA implies a close relationship with fungi.

    Saundra L. Stringer;James R. Stringer;Maria A. Blase;Peter D. Walzer

  • Echinocandin treatment of pneumocystis pneumonia in rodent models depletes cysts leaving trophic burdens that cannot transmit the infection.

    Melanie T. Cushion;Melanie T. Cushion;Michael J. Linke;Alan Ashbaugh;Alan Ashbaugh;Tom Sesterhenn;Tom Sesterhenn

  • Reliability of calcein acetoxy methyl ester and ethidium homodimer or propidium iodide for viability assessment of microbes

    Edna S. Kaneshiro;Michael A. Wyder;Yi-Ping Wu;Melanie T. Cushion

  • Pneumocystis and Trypanosoma cruzi: nomenclature and typifications.

    Scott A. Redhead;Melanie T. Cushion;Jacob K. Frenkel;James R. Stringer

  • Genetic stability and diversity of Pneumocystis carinii infecting rat colonies.

    M T Cushion;M Kaselis;S L Stringer;J R Stringer

  • Pneumocystis carinii karyotypes.

    Sung-Tae Hong;P. E. Steele;M. T. Cushion;P. D. Walzer

  • Properties of the major antigens of rat and human Pneumocystis carinii.

    M J Linke;M T Cushion;P D Walzer

  • Evidence for two genetic variants of Pneumocystis carinii coinfecting laboratory rats.

    M. T. Cushion;Jianxiong Zhang;M. Kaselis;D. Giuntoli

  • Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids

    Visesato Mor;Antonella Rella;Amir M. Farnoud;Ashutosh Singh

  • Molecular Genetic Distinction of Pneumocystis carinii from Rats and Humans

    J. R. Stringer;S. L. Stringer;Jianxiong Zhang;R. Baughman

  • Pneumocystis activates human alveolar macrophage NF-kappaB signaling through mannose receptors

    Jianmin Zhang;Jinping Zhu;Amy Imrich;Melanie Cushion

  • Negative regulatory role of mannose receptors on human alveolar macrophage proinflammatory cytokine release in vitro.

    Jianmin Zhang;Souvenir D. Tachado;Naimish Patel;Jinping Zhu

  • Growth and serial passage of Pneumocystis carinii in the A549 cell line.

    M T Cushion;P D Walzer

  • Pneumocystis oryctolagi sp. nov., an uncultured fungus causing pneumonia in rabbits at weaning: review of current knowledge, and description of a new taxon on genotypic, phylogenetic and phenotypic bases.

    Eduardo Dei-Cas;Magali Chabé;Raya Moukhlis;Isabelle Durand-Joly

  • Phylogenomic Analyses Support the Monophyly of Taphrinomycotina, including Schizosaccharomyces Fission Yeasts

    Yu Liu;Jessica W. Leigh;Henner Brinkmann;Melanie T. Cushion

  • The challenge of Pneumocystis carinii culture.

    Elaine Sloand;Barbara Laughon;Martine Armstrong;Marilyn S. Bartlett

  • New Nomenclature for the Genus Pneumocystis

    James R. Stringer;Melanie T. Cushion;Ann E. Wakefield

  • Analysis of the developmental stages of Pneumocystis carinii, in vitro.

    Cushion Mt;Ruffolo Jj;Walzer Pd

  • Biofilm Formation by Pneumocystis spp.

    Melanie T. Cushion;Margaret S. Collins;Michael J. Linke

  • Cdc42 and RhoB Activation Are Required for Mannose Receptor-mediated Phagocytosis by Human Alveolar Macrophages

    Jianmin Zhang;Jinping Zhu;Xia Bu;Melanie Cushion

  • The ste3 Pheromone Receptor Gene of Pneumocystis carinii Is Surrounded by a Cluster of Signal Transduction Genes

    A. George Smulian;A. George Smulian;Thomas Sesterhenn;Reiko Tanaka;Melanie T. Cushion;Melanie T. Cushion

Frequent Co-Authors

Peter D. Walzer
Peter D. Walzer University of Cincinnati
James R. Stringer
James R. Stringer University of Cincinnati
Joseph A. Kovacs
Joseph A. Kovacs National Institutes of Health
Louis M. Weiss
Louis M. Weiss Albert Einstein College of Medicine
Koen K. A. Van Rompay
Koen K. A. Van Rompay University of California, Davis
Vanessa M. Hirsch
Vanessa M. Hirsch National Institute of Allergy and Infectious Diseases
Christina A. Cuomo
Christina A. Cuomo Broad Institute
Marcio L. Rodrigues
Marcio L. Rodrigues Federal University of Rio de Janeiro
Jason M. Brenchley
Jason M. Brenchley National Institute of Allergy and Infectious Diseases
Nathan P. Wiederhold
Nathan P. Wiederhold The University of Texas Health Science Center at San Antonio

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