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Neuroscience

D-Index
50
Citations
9709
World Ranking
5722
National Ranking
2527

Overview

Hoon Chul Kang is affiliated with Boston Children's Hospital in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics, and Molecular Biology, with significant contributions across multiple subfields including Psychiatry and Mental Health, Genetics, Molecular Biology, Pediatrics, Perinatology and Child Health, and Neurology.

Their work focuses on a variety of topics, particularly in epilepsy research and treatment, genomics and rare diseases, as well as genetics and neurodevelopmental disorders. Additional research interests include pharmacological effects and toxicity studies, neuroscience and neuropharmacology research, fetal and pediatric neurological disorders, and diet and metabolism studies.

Notable recent publications demonstrate a breadth of investigation in neuroscience and genetics:

  • Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids, 2021, Nature Communications
  • Sequence-specific prediction of the efficiencies of adenine and cytosine base editors, 2020, Nature Biotechnology
  • Frequent SLC35A2 brain mosaicism in mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE), 2021, Acta Neuropathologica Communications
  • Comprehensive multi-omic profiling of somatic mutations in malformations of cortical development, 2023, Nature Genetics
  • Clinical Features, Neuropathology, and Surgical Outcome in Patients With Refractory Epilepsy and Brain Somatic Variants in the SLC35A2 Gene, 2022, Neurology

Frequent coauthors in their research include:

  • Heung Dong Kim (48 collaborations)
  • Se Hee Kim (46 collaborations)
  • Joon Soo Lee (45 collaborations)
  • Ara Ko (19 collaborations)
  • Hui Jin Shin (12 collaborations)

Hoon Chul Kang has published extensively in several academic venues, with multiple contributions to:

  • Annals of Child Neurology (13 publications)
  • Epilepsy Research (9 publications)
  • Journal of Clinical Neurology (6 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (4 publications)
  • Hematology Transfusion and Cell Therapy (4 publications)

Best Publications

  • Optimal clinical management of children receiving dietary therapies for epilepsy: Updated recommendations of the International Ketogenic Diet Study Group

    Eric H. Kossoff;Beth A. Zupec‐Kania;Stéphane Auvin;Karen R. Ballaban‐Gil

  • Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy

    Jae Seok Lim;Woo Il Kim;Hoon Chul Kang;Se Hoon Kim

  • Early- and Late-onset Complications of the Ketogenic Diet for Intractable Epilepsy

    Hoon Chul Kang;Da Eun Chung;Dong Wook Kim;Heung Dong Kim

  • Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids

    Ann-Na Cho;Yoonhee Jin;Yeonjoo An;Jin Kim

  • Safe and Effective Use of the Ketogenic Diet in Children with Epilepsy and Mitochondrial Respiratory Chain Complex Defects

    Hoon Chul Kang;Young Mock Lee;Heung Dong Kim;Joon Soo Lee

  • Efficacy and Safety of the Ketogenic Diet for Intractable Childhood Epilepsy : Korean Multicentric Experience

    Hoon Chul Kang;Yong Joo Kim;Dong Wook Kim;Heung Dong Kim

  • Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia

    Jae Seok Lim;Ramu Gopalappa;Se Hoon Kim;Suresh Ramakrishna

  • Efficacy and tolerability of the ketogenic diet according to lipid:nonlipid ratios--comparison of 3:1 with 4:1 diet.

    Joo Hee Seo;Young Mock Lee;Joon Soo Lee;Hoon Chul Kang

  • Efficacy of the classic ketogenic and the modified Atkins diets in refractory childhood epilepsy.

    Jeong A. Kim;Jung Rim Yoon;Eun Joo Lee;Joon Soo Lee

  • Benefits of the nonfasting ketogenic diet compared with the initial fasting ketogenic diet.

    Dong Wook Kim;Hoon Chul Kang;Jung Chae Park;Heung Dong Kim

  • Mitochondrial respiratory chain defects: Underlying etiology in various epileptic conditions

    Young Mock Lee;Hoon Chul Kang;Joon Soo Lee;Se Hoon Kim

  • 25-hydroxycholesterol contributes to cerebral inflammation of X-linked adrenoleukodystrophy through activation of the NLRP3 inflammasome

    Jiho Jang;Sangjun Park;Hye Jin Hur;Hyun Ju Cho

  • Use of a modified Atkins diet in intractable childhood epilepsy.

    Hoon Chul Kang;Hyun Sug Lee;Su Jeong You;Du Cheol Kang

  • Ketogenic diet for treatment of infantile spasms

    So Hee Eun;Hoon Chul Kang;Dong Wook Kim;Heung Dong Kim

  • Precise detection of low-level somatic mutation in resected epilepsy brain tissue

    Nam Suk Sim;Ara Ko;Woo Kyeong Kim;Se Hoon Kim

  • Neuroimaging in identifying focal cortical dysplasia and prognostic factors in pediatric and adolescent epilepsy surgery

    Yoon Hee Kim;Hoon Chul Kang;Dong Seok Kim;Se Hoon Kim

  • Resective pediatric epilepsy surgery in Lennox-Gastaut syndrome.

    Yun Jin Lee;Hoon Chul Kang;Joon Soo Lee;Shin Hye Kim

  • An AKT3-FOXG1-reelin network underlies defective migration in human focal malformations of cortical development

    Seung Tae Baek;Brett Copeland;Eun Jin Yun;Seok Kyu Kwon

  • Comparison of corpus callosotomy and vagus nerve stimulation in children with Lennox-Gastaut syndrome

    Su Jeong You;Hoon Chul Kang;Tae Sung Ko;Heung Dong Kim

  • BRAF somatic mutation contributes to intrinsic epileptogenicity in pediatric brain tumors

    Hyun Yong Koh;Se Hoon Kim;Jaeson Jang;Hyungguk Kim

  • Disease-specific induced pluripotent stem cells: a platform for human disease modeling and drug discovery

    Jiho Jang;Jeong Eun Yoo;Jeong Ah Lee;Dongjin R. Lee

Frequent Co-Authors

Heung Dong Kim
Heung Dong Kim Yonsei University Health System
Joseph G. Gleeson
Joseph G. Gleeson University of California, San Diego
Seung-Koo Lee
Seung-Koo Lee Yonsei University
Seung Woo Cho
Seung Woo Cho Yonsei University
Byung In Lee
Byung In Lee Inje University
Eleonora Aronica
Eleonora Aronica University of Amsterdam
Ingrid E. Scheffer
Ingrid E. Scheffer University of Melbourne
Eric H. Kossoff
Eric H. Kossoff Johns Hopkins University
Douglas R. Nordli
Douglas R. Nordli University of Chicago
Phil Hyu Lee
Phil Hyu Lee Yonsei University

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