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Jan Pravsgaard Christensen

Jan Pravsgaard Christensen

D-Index & Metrics

Immunology

D-Index
51
Citations
9700
World Ranking
4146
National Ranking
42

Overview

Jan Pravsgaard Christensen is affiliated with the University of Copenhagen in Denmark and has a significant body of work in medicine, particularly focusing on immunology and microbiology. Their research primarily addresses subfields such as immunology, infectious diseases, molecular biology, epidemiology, and neurology.

Their main research topics include immune cell function and interaction, immunotherapy and immune responses, T-cell and B-cell immunology, neuroinflammation and neurodegeneration mechanisms, SARS-CoV-2 and COVID-19 research, influenza virus research studies, and vaccines and immunoinformatics approaches.

Jan Pravsgaard Christensen has published extensively in several academic journals. The most frequent publication venues include Frontiers in Immunology, The Journal of Immunology, bioRxiv (Cold Spring Harbor Laboratory), Journal of Immunological Methods, and eLife.

The scientist has collaborated with various co-authors, some of the most frequent being Allan Randrup Thomsen, Ida Uddbäck, Jacob E. Kohlmeier, Søren Buus, and Anette Stryhn.

Recent papers by Jan Pravsgaard Christensen illustrate the scope of their research:

  • Cytotoxic CD8+ T cells in cancer and cancer immunotherapy, 2020, British Journal of Cancer
  • Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity, 2021, Nature Communications
  • Long-term maintenance of lung resident memory T cells is mediated by persistent antigen, 2020, Mucosal Immunology
  • Prevention of respiratory virus transmission by resident memory CD8+ T cells, 2023, Nature
  • MHC class II invariant chain-adjuvanted viral vectored vaccines enhances T cell responses in humans, 2020, Science Translational Medicine

Best Publications

  • Cytotoxic CD8 + T cells in cancer and cancer immunotherapy

    Hans Raskov;Adile Orhan;Jan Pravsgaard Christensen;Ismail Gögenur

  • Accessing complexity: the dynamics of virus-specific T cell responses.

    Peter C. Doherty;Jan P. Christensen

  • A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin

    Kristoffer L. Egerod;Maja S. Engelstoft;Kaare V. Grunddal;Mark K. Nøhr

  • In vivo proliferation of naïve and memory influenza-specific CD8+ T cells

    Kirsten J. Flynn;Janice M. Riberdy;Jan P. Christensen;John D. Altman

  • Exhaustion of CTL memory and recrudescence of viremia in lymphocytic choriomeningitis virus-infected MHC class II-deficient mice and B cell-deficient mice.

    A R Thomsen;J Johansen;O Marker;J P Christensen

  • Diminished Primary and Secondary Influenza Virus-Specific CD8+ T-Cell Responses in CD4-Depleted Ig−/− Mice

    Janice M. Riberdy;Jan P. Christensen;Kristen Branum;Peter C. Doherty

  • The importance of lytic and nonlytic immune responses in viral infections

    Dominik Wodarz;Jan Pravsgaard Christensen;Allan Randrup Thomsen

  • Dissecting the host response to a gamma-herpesvirus.

    Peter C. Doherty;Jan P. Christensen;Gabrielle T. Belz;Philip G. Stevenson

  • CD4(+) T cell-mediated control of a gamma-herpesvirus in B cell-deficient mice is mediated by IFN-gamma.

    Jan P. Christensen;Rhonda D. Cardin;Kristen C. Branum;Peter C. Doherty

  • CXCL10 Is the Key Ligand for CXCR3 on CD8+ Effector T Cells Involved in Immune Surveillance of the Lymphocytic Choriomeningitis Virus-Infected Central Nervous System

    Jeanette Erbo Christensen;Carina de Lemos;Torben Moos;Jan Pravsgaard Christensen

  • Profound Protection against Respiratory Challenge with a Lethal H7N7 Influenza A Virus by Increasing the Magnitude of CD8+ T-Cell Memory

    Jan P. Christensen;Peter C. Doherty;Kristen C. Branum;Janice M. Riberdy

  • Persistent Virus Infection despite Chronic Cytotoxic T-Lymphocyte Activation in Gamma Interferon-Deficient Mice Infected with Lymphocytic Choriomeningitis Virus

    Christina Bartholdy;Jan Pravsgaard Christensen;Dominik Wodarz;Allan Randrup Thomsen

  • CXCR3 Directs Antigen-Specific Effector CD4+ T Cell Migration to the Lung During Parainfluenza Virus Infection

    Jacob E. Kohlmeier;Tres Cookenham;Shannon C. Miller;Alan D. Roberts

  • Changes in cell adhesion molecule expression on T cells associated with systemic virus infection.

    E C Andersson;J P Christensen;O Marker;A R Thomsen

  • A cationic vaccine adjuvant based on a saturated quaternary ammonium lipid have different in vivo distribution kinetics and display a distinct CD4 T cell-inducing capacity compared to its unsaturated analog.

    Dennis Christensen;Malou Henriksen-Lacey;Arun T. Kamath;Thomas Lindenstrøm

  • Molecular pharmacological phenotyping of EBI2. An orphan seven-transmembrane receptor with constitutive activity.

    Mette M. Rosenkilde;Tau Benned-Jensen;Helene Andersen;Peter J. Holst

  • Immunological control of a murine gammaherpesvirus independent of CD8+ T cells.

    P G Stevenson;R D Cardin;J P Christensen;P C Doherty

  • CD11b expression as a marker to distinguish between recently activated effector CD8(+) T cells and memory cells.

    Unknown

  • Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity.

    Cyrielle Fougeroux;Louise Goksøyr;Manja Idorn;Vladislav Soroka

  • Cooperation of B cells and T cells is required for survival of mice infected with vesicular stomatitis virus.

    Allan Randrup Thomsen;Anneline Nansen;Camilla Andersen;Jørn Johansen

  • The role of CC chemokine receptor 5 in antiviral immunity.

    Anneline Nansen;Jan Pravsgaard Christensen;Susanne Ørding Andreasen;Christina Bartholdy

  • Compromised virus control and augmented perforin-mediated immunopathology in IFN-gamma-deficient mice infected with lymphocytic choriomeningitis virus.

    Anneline Nansen;Teis Jensen;Jan Pravsgaard Christensen;Susanne Ørding Andreasen

Frequent Co-Authors

Allan Randrup Thomsen
Allan Randrup Thomsen University of Copenhagen
Peter C. Doherty
Peter C. Doherty University of Melbourne
Peter E. Andersen
Peter E. Andersen Technical University of Denmark
Søren Buus
Søren Buus University of Copenhagen
Dominik Wodarz
Dominik Wodarz University of California, Irvine
Niels Ødum
Niels Ødum University of Copenhagen
Torben Moos
Torben Moos Aalborg University
Gabrielle T. Belz
Gabrielle T. Belz University of Queensland
Thue W. Schwartz
Thue W. Schwartz University of Copenhagen
Philip G. Stevenson
Philip G. Stevenson University of Queensland

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