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Biology and Biochemistry
Denmark
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
110
Citations
40815
World Ranking
974
National Ranking
9

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Denmark Leader Award
  • 2025 - Research.com Biology and Biochemistry in Denmark Leader Award
  • 2023 - Research.com Biology and Biochemistry in Denmark Leader Award
  • 2022 - Research.com Biology and Biochemistry in Denmark Leader Award

Overview

Thue W. Schwartz is affiliated with the University of Copenhagen in Denmark. Their research primarily spans the fields of Medicine as well as Biochemistry, Genetics and Molecular Biology, with a focus on several subfields including Molecular Biology, Physiology, Epidemiology, Cellular and Molecular Neuroscience, and Endocrinology, Diabetes and Metabolism.

The topics addressed in their body of work include:

  • Receptor Mechanisms and Signaling
  • Diet and metabolism studies
  • Adipose Tissue and Metabolism
  • Neuropeptides and Animal Physiology
  • Adipokines, Inflammation, and Metabolic Diseases
  • Diabetes Treatment and Management
  • Regulation of Appetite and Obesity

Among the recent papers authored or co-authored by Schwartz are:

  • "snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis," 2020, Nature
  • "Microbiome-derived ethanol in nonalcoholic fatty liver disease," 2022, Nature Medicine
  • "Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling," 2021, Cell Reports
  • "Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis," 2021, Cell
  • "L-Cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling," 2020, Diabetes

Frequently, Schwartz collaborates with several researchers, including:

  • Mette Trauelsen
  • Thomas M. Frimurer
  • Oksana Dmytriyeva
  • Fredrik Bäckhed
  • Jacob E. Petersen

The principal publication venues for Schwartz's work feature several journals, notably:

  • Molecular Metabolism
  • Nature
  • Cell Reports
  • Diabetes
  • Cell Metabolism

This profile reflects a research portfolio that encompasses molecular biology and metabolic studies with a particular focus on receptors, signaling pathways, and physiological regulation related to metabolism and diabetes. Schwartz's publications consistently contribute to understanding complex biochemical and physiological mechanisms in these domains.

Best Publications

  • Glucagon-like peptide 1 (GLP-1)

    T.D. Müller;B. Finan;S.R. Bloom;D. D'Alessio

  • XVI. International Union of Pharmacology Recommendations for the Nomenclature of Neuropeptide Y, Peptide YY, and Pancreatic Polypeptide Receptors

    Martin C. Michel;Annette Beck-Sickinger;Helen Cox;Henri N. Doods

  • Potent Inhibition of HIV-1 Infectivity in Macrophages and Lymphocytes by a Novel CCR5 Antagonist

    Graham Simmons;Paul R. Clapham;Laurent Picard;Robin E. Offord

  • Truncated glucagon-like peptide I, an insulin-releasing hormone from the distal gut

    J.J. Holst;C. Ørskov;O. Vagn Nielsen;T.W. Schwartz

  • High constitutive signaling of the ghrelin receptor--identification of a potent inverse agonist.

    Birgitte Holst;Adam Cygankiewicz;Tine Halkjær Jensen;Michael Ankersen

  • A broad-spectrum chemokine antagonist encoded by Kaposi's sarcoma-associated herpesvirus

    Thomas N. Kledal;Mette M. Rosenkilde;Florence Coulin;Graham Simmons

  • Somatostatin cell processes as pathways for paracrine secretion

    LI Larsson;N Goltermann;L de Magistris;JF Rehfeld

  • Pancreatic polypeptide: a hormone under vagal control.

    Thue W. Schwartz

  • GPCR-Mediated Signaling of Metabolites

    Anna Sofie Husted;Mette Trauelsen;Olga Rudenko;Siv A. Hjorth

  • Vagal, Cholinergic Regulation of Pancreatic Polypeptide Secretion

    T. W. Schwartz;J. J. Holst;J. Fahrenkrug;S. Lindkær Jensen

  • GPR41/FFAR3 and GPR43/FFAR2 as Cosensors for Short-Chain Fatty Acids in Enteroendocrine Cells vs FFAR3 in Enteric Neurons and FFAR2 in Enteric Leukocytes

    Mark K. Nøhr;Maria H. Pedersen;Andreas Gille;Kristoffer L. Egerod

  • GPR39 Signaling Is Stimulated by Zinc Ions But Not by Obestatin

    Birgitte Holst;Kristoffer L. Egerod;Enrico Schild;Steve P. Vickers

  • MOLECULAR MECHANISM OF 7TM RECEPTOR ACTIVATION—A GLOBAL TOGGLE SWITCH MODEL

    Thue W Schwartz;Thomas M Frimurer;Birgitte Holst;Mette M Rosenkilde

  • Phorbol Esters and SDF-1 Induce Rapid Endocytosis and Down Modulation of the Chemokine Receptor CXCR4

    Natalie Signoret;Joanne Oldridge;Annegret Pelchen-Matthews;Per J. Klasse

  • [Leu31, Pro34]neuropeptide Y: a specific Y1 receptor agonist

    Jannie Fuhlendorff;Ulrik Gether;Lars Aakerlund;Nils Langeland-Johansen

  • International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein–Coupled Receptors

    Jörg Hamann;Gabriela Aust;Demet Araç;Felix B. Engel

  • Ligand binding and micro-switches in 7TM receptor structures

    Rie Nygaard;Thomas M. Frimurer;Birgitte Holst;Mette M. Rosenkilde

  • PANCREATIC SOMATOSTATINOMA: Clinical Features and Physiological Implications

    L.-I. Larsson;J.J. Holst;C. Kühl;G. Lundqvist

  • Locating ligand-binding sites in 7TM receptors by protein engineering.

    Thue W Schwartz

  • Molecular interactions of cyclam and bicyclam non-peptide antagonists with the CXCR4 chemokine receptor.

    Lars Ole Gerlach;Renato T. Skerlj;Gary J. Bridger;Thue W. Schwartz

Frequent Co-Authors

Mette M. Rosenkilde
Mette M. Rosenkilde University of Copenhagen
Jens J. Holst
Jens J. Holst University of Copenhagen
Ulrik Gether
Ulrik Gether University of Copenhagen
Jens F. Rehfeld
Jens F. Rehfeld University of Copenhagen
Annette G. Beck-Sickinger
Annette G. Beck-Sickinger Leipzig University
Torben Hansen
Torben Hansen University of Copenhagen
Fredrik Bäckhed
Fredrik Bäckhed University of Gothenburg
Oluf Pedersen
Oluf Pedersen University of Copenhagen
Gary J. Bridger
Gary J. Bridger Liminal BioSciences (Canada)
Fiona M. Gribble
Fiona M. Gribble University of Cambridge

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