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Genetics

D-Index
66
Citations
15755
World Ranking
2615
National Ranking
120

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Henri Grosjean is affiliated with the Centre national de la recherche scientifique (CNRS) in France. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with additional work in environmental science. The molecular biology subfield forms a core part of their studies.

The scientist's main research topics include:

  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • Genomics and phylogenetic studies
  • Parasitic infections and diagnostics
  • Bacteriophages and microbial interactions
  • Microbial community ecology and physiology
  • Peptidase inhibition and analysis

Henri Grosjean has published extensively in multiple scientific journals. Frequent publication venues include:

  • RNA (3 publications)
  • Genes (1 publication)
  • Nucleic Acids Research (1 publication)
  • Biomolecules (1 publication)
  • Preprints.org (1 publication)

Some recent papers authored or coauthored by Grosjean are:

  • "Comparative patterns of modified nucleotides in individual tRNA species from a mesophilic and two thermophilic archaea," 2020, RNA
  • "Post-Transcriptional Modifications of Conserved Nucleotides in the T-Loop of tRNA: A Tale of Functional Convergent Evolution," 2021, Genes
  • "The hyperthermophilic partners Nanoarchaeum and Ignicoccus stabilize their tRNA T-loops via different but structurally equivalent modifications," 2020, Nucleic Acids Research
  • "Reductive Evolution and Diversification of C5-Uracil Methylation in the Nucleic Acids of Mollicutes," 2020, Biomolecules
  • "Identification of Up47 in three thermophilic archaea, one mesophilic archaeon, and one hyperthermophilic bacterium," 2023, RNA

Frequent coauthors working with Grosjean include:

  • Louis Droogmans
  • Philippe Wolff
  • Éric Westhof
  • Simon Rose
  • Stephen Douthwaite

Grosjean has also been recognized as a member of the European Molecular Biology Organization (EMBO), reflecting engagement with the scientific community.

Best Publications

  • Preferential codon usage in prokaryotic genes: the optimal codon-anticodon interaction energy and the selective codon usage in efficiently expressed genes.

    Henri Grosjean;Walter Fiers

  • MODOMICS: a database of RNA modification pathways—2013 update

    Magdalena A. Machnicka;Kaja Milanowska;Okan Osman Oglou;Elzbieta Purta

  • tRNomics: analysis of tRNA genes from 50 genomes of Eukarya, Archaea, and Bacteria reveals anticodon-sparing strategies and domain-specific features.

    Christian Marck;Henri Grosjean

  • Modification And Editing Of Rna

    Henri Grosjean;Rob Benne

  • On the physical basis for ambiguity in genetic coding interactions

    H J Grosjean;S de Henau;D M Crothers

  • MODOMICS: a database of RNA modification pathways

    Stanislaw Dunin-Horkawicz;Anna Czerwoniec;Michal J. Gajda;Marcin Feder

  • Deciphering synonymous codons in the three domains of life: co-evolution with specific tRNA modification enzymes.

    Henri Grosjean;Valérie de Crécy-Lagard;Christian Marck

  • Relaxation of a transfer RNA specificity by removal of modified nucleotides.

    Véronique Perret;Angela Garcia;Henri Grosjean;Jean-Pierre Ebel

  • Studies of the complex between transfer RNAs with complementary anticodons. I. Origins of enhanced affinity between complementary triplets.

    H. Grosjean;D.G. Söll;D.M. Crothers

  • MODOMICS: a database of RNA modification pathways. 2008 update

    Anna Czerwoniec;Stanislaw Dunin-Horkawicz;Elzbieta Purta;Katarzyna H. Kaminska

  • Pseudouridine Mapping in the Saccharomyces cerevisiae Spliceosomal U Small Nuclear RNAs (snRNAs) Reveals that Pseudouridine Synthase Pus1p Exhibits a Dual Substrate Specificity for U2 snRNA and tRNA

    Séverine Massenet;Yuri Motorin;Denis L. J. Lafontaine;Eduard C. Hurt

  • Queuosine modification of the wobble base in tRNAHis influences ‘in vivo’ decoding properties.

    F Meier;B Suter;H Grosjean;G Keith

  • Multisite-specific tRNA:m5C-methyltransferase (Trm4) in yeast Saccharomyces cerevisiae: identification of the gene and substrate specificity of the enzyme.

    Yuri Motorin;Henri Grosjean

  • Trm7p catalyses the formation of two 2'-O-methylriboses in yeast tRNA anticodon loop.

    Lionel Pintard;François Lecointe;Janusz M. Bujnicki;Claire Bonnerot

  • The yeast gene YNL292w encodes a pseudouridine synthase (Pus4) catalyzing the formation of psi55 in both mitochondrial and cytoplasmic tRNAs.

    H F Becker;Y Motorin;R J Planta;H Grosjean

  • Tad1p, a yeast tRNA‐specific adenosine deaminase, is related to the mammalian pre‐mRNA editing enzymes ADAR1 and ADAR2

    André Gerber;Henri Grosjean;Thorsten Melcher;Walter Keller

  • Posttranscriptionally modified nucleosides in transfer RNA: their locations and frequencies.

    H. Grosjean;M. Sprinzl;S. Steinberg

  • Distribution and frequencies of post-transcriptional modifications in tRNAs

    Magdalena A Machnicka;Anna Olchowik;Henri Grosjean;Janusz M Bujnicki

  • Conformation in solution of yeast tRNA(Asp) transcripts deprived of modified nucleotides.

    Véronique Perret;A Garcia;J Puglisi;H Grosjean

  • Characterization of Yeast Protein Deg1 as Pseudouridine Synthase (Pus3) Catalyzing the Formation of Ψ38 and Ψ39 in tRNA Anticodon Loop

    François Lecointe;George Simos;Anke Sauer;Eduard C. Hurt

Frequent Co-Authors

Gérard Keith
Gérard Keith Centre national de la recherche scientifique, CNRS
Robert Cedergren
Robert Cedergren University of Montreal
Richard Giegé
Richard Giegé Centre national de la recherche scientifique, CNRS
Valérie de Crécy-Lagard
Valérie de Crécy-Lagard University of Florida
Guy Dirheimer
Guy Dirheimer Centre national de la recherche scientifique, CNRS
Céline Brochier-Armanet
Céline Brochier-Armanet Claude Bernard University Lyon 1
Catherine Florentz
Catherine Florentz University of Strasbourg
Jean Armengaud
Jean Armengaud Atomic Energy and Alternative Energies Commission
George Simos
George Simos University Of Thessaly

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