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Chemistry

D-Index
53
Citations
8952
World Ranking
13194
National Ranking
3471

Research.com Recognitions

  • 2013 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Patrick A. Limbach is affiliated with the University of Cincinnati in the United States. Their research focuses primarily on the field of Biochemistry, Genetics, and Molecular Biology, with a substantial body of work concentrated in Molecular Biology, Cancer Research, Epidemiology, Oncology, and Biomedical Engineering.

The scientist has contributed extensively to topics related to RNA modifications and cancer, RNA and protein synthesis mechanisms, RNA research and splicing, cancer-related molecular mechanisms research, cancer-related gene regulation, genomics and phylogenetic studies, and peptidase inhibition and analysis.

Frequent co-authors collaborating with Patrick A. Limbach include:

  • Balasubrahmanyam Addepalli
  • Cassandra Herbert
  • Robert Ross
  • Melissa Kelley
  • Manasses Jora

Patrick A. Limbach has published in several well-known scientific venues, with multiple publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • Biomolecules
  • Nature Cell Biology
  • Proceedings of the National Academy of Sciences

Selected recent papers authored or co-authored by Patrick A. Limbach include:

  • Downregulation of the FTO m6A RNA demethylase promotes EMT-mediated progression of epithelial tumors and sensitivity to Wnt inhibitors, 2021, Nature Cancer
  • Instrumental analysis of RNA modifications, 2021, Critical Reviews in Biochemistry and Molecular Biology
  • Survey and Validation of tRNA Modifications and Their Corresponding Genes in Bacillus subtilis sp Subtilis Strain 168, 2020, Biomolecules
  • Preferential import of queuosine-modified tRNAs into Trypanosoma brucei mitochondrion is critical for organellar protein synthesis, 2021, Nucleic Acids Research
  • Dynamic queuosine changes in tRNA couple nutrient levels to codon choice in Trypanosoma brucei, 2021, Nucleic Acids Research

In 2013, Patrick A. Limbach was named a Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • Summary: the modified nucleosides of RNA

    Patrick A. Limbach;Pamela F. Crain;James A. McCloskey

  • The autofluorescence of plastic materials and chips measured under laser irradiation

    Aigars Piruska;Irena Nikcevic;Se Hwan Lee;Chong Ahn

  • Observation of the doubly charged, gas-phase fullerene anions C602- and C702-

    Patrick A. Limbach;Lutz Schweikhard;Kenneth A. Cowen;Mark T. McDermott

  • Indirect mass spectrometric methods for characterizing and sequencing oligonucleotides.

    Patrick A. Limbach

  • Molecular mass measurement of intact ribonucleic acids via electrospray ionization quadrupole mass spectrometry

    Patrick A. Limbach;Pamela F. Crain;James A. McCloskey

  • Experimental determination of the number of trapped ions, detection limit, and dynamic range in Fourier transform ion cyclotron resonance mass spectrometry

    Patrick A. Limbach;Peter B. Grosshans;Alan G. Marshall

  • Electron-transfer ionization in matrix-assisted laser desorption/ionization mass spectrometry

    Tracy Donovan McCarley;Robin L. McCarley;Patrick A. Limbach

  • Proteomic, Microarray, and Signature-Tagged Mutagenesis Analyses of Anaerobic Pseudomonas aeruginosa at pH 6.5, Likely Representing Chronic, Late-Stage Cystic Fibrosis Airway Conditions

    Mark D. Platt;Michael J. Schurr;Karin Sauer;Gustavo Vazquez

  • Agmatidine, a modified cytidine in the anticodon of archaeal tRNA Ile , base pairs with adenosine but not with guanosine

    Debabrata Mandal;Caroline Köhrer;Dan Su;Susan P. Russell

  • Characterization of oligonucleotides and nucleic acids by mass spectrometry

    Patrick A Limbach;Pamela F Crain;James A McCloskey

  • Mass spectrometry of modified RNAs: recent developments

    Collin Wetzel;Patrick A. Limbach

  • Mononucleotide gas-phase proton affinities as determined by the kinetic method

    Kari B. Green-Church;Patrick A. Limbach

  • Yeast Trm7 interacts with distinct proteins for critical modifications of the tRNAPhe anticodon loop.

    Michael P. Guy;Brandon M. Podyma;Melanie A. Preston;Hussam H. Shaheen

  • Mass spectrometry-based detection of transfer RNAs by their signature endonuclease digestion products.

    Mahmud Hossain;Patrick A. Limbach

  • Oligonucleotide analysis by hydrophilic interaction liquid chromatography-mass spectrometry in the absence of ion-pair reagents.

    Peter A. Lobue;Manasses Jora;Balasubrahmanyam Addepalli;Patrick A. Limbach

  • Sequence mapping of transfer RNA chemical modifications by liquid chromatography tandem mass spectrometry

    Robert Ross;Xiaoyu Cao;Ningxi Yu;Patrick A. Limbach

  • The identification and characterization of non-coding and coding RNAs and their modified nucleosides by mass spectrometry

    Kirk W Gaston;Patrick A Limbach

  • On-Line Sample Preconcentration Using Field-amplified Stacking Injection in Microchip Capillary Electrophoresis

    Maojun Gong;Kenneth R. Wehmeyer;Patrick A. Limbach;Francisco Arias

  • Influence of ionization energy on charge-transfer ionization in matrix-assisted laser desorption/ionization mass spectrometry

    Stephen F. Macha;Tracy D. McCarley;Patrick A. Limbach

  • Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry of polymers

    Stephen F Macha;Patrick A Limbach

  • Electrospray ionization mass spectrometry of metalloporphyrins.

    Victor E. Vandell;Patrick A. Limbach

Frequent Co-Authors

William R. Heineman
William R. Heineman University of Cincinnati
Alan G. Marshall
Alan G. Marshall Florida State University
Valérie de Crécy-Lagard
Valérie de Crécy-Lagard University of Florida
H. Brian Halsall
H. Brian Halsall University of Cincinnati
James A. McCloskey
James A. McCloskey University of Utah
Joseph A. Caruso
Joseph A. Caruso Wayne State University
Albert E. Dahlberg
Albert E. Dahlberg Brown University
Chong H. Ahn
Chong H. Ahn University of Cincinnati

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