2009 - Fellow of the American Association for the Advancement of Science (AAAS)
The scientist’s investigation covers issues in Biochemistry, RNA, Transfer RNA, Mass spectrometry and Chromatography. His works in Hyperthermophile, Dihydrouridine, Nucleoside, RNase P and Pseudouridine are all subjects of inquiry into Biochemistry. James A. McCloskey has researched RNA in several fields, including Ribosomal RNA, Nucleic acid and Nucleotide.
In his study, which falls under the umbrella issue of Nucleic acid, Deamination is strongly linked to Adenosine. His Transfer RNA research focuses on Ribosome and how it relates to Methanococcus, Methanococcus maripaludis, Wybutosine and Methanococcales. He focuses mostly in the field of Mass spectrometry, narrowing it down to topics relating to Oligonucleotide and, in certain cases, Nucleic acid sequence and Ribonuclease T1.
James A. McCloskey spends much of his time researching Biochemistry, Mass spectrometry, Transfer RNA, Stereochemistry and Chromatography. His study in Biochemistry concentrates on RNA, Nucleoside, Ribosomal RNA, Escherichia coli and Nucleotide. James A. McCloskey has included themes like Hyperthermophile, Molecular mass and Ribose in his RNA study.
His studies deal with areas such as Nucleic acid, Organic chemistry and Oligonucleotide as well as Mass spectrometry. His studies in Transfer RNA integrate themes in fields like Thermophile and Cytidine. His Stereochemistry study combines topics in areas such as Guanosine and Adenosine.
His primary scientific interests are in Biochemistry, RNA, Transfer RNA, Oligonucleotide and Mass spectrometry. His RNA study integrates concerns from other disciplines, such as Hyperthermophile, Archaea, Ribosomal RNA and Escherichia coli. The Transfer RNA study combines topics in areas such as Amino acid and Nucleoside.
His research in Oligonucleotide intersects with topics in RNase P and Electrospray ionization. His Mass spectrometry study results in a more complete grasp of Chromatography. The various areas that James A. McCloskey examines in his Tandem mass spectrometry study include Mass spectrum and Stereochemistry, Pyrimidine.
James A. McCloskey mostly deals with Biochemistry, RNA, Transfer RNA, Hyperthermophile and Oligonucleotide. His research on Biochemistry focuses in particular on 23S ribosomal RNA. His work on Modified nucleosides as part of general RNA study is frequently linked to Database and Index, therefore connecting diverse disciplines of science.
His Transfer RNA study frequently intersects with other fields, such as Methanococcus maripaludis. His Oligonucleotide research is multidisciplinary, relying on both Capillary electrophoresis–mass spectrometry, Trans-translation, Mass spectrum, Mass spectrometry and Nucleic acid sequence. His Mass spectrometry study is associated with Chromatography.
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Summary: the modified nucleosides of RNA
Patrick A. Limbach;Pamela F. Crain;James A. McCloskey.
Nucleic Acids Research (1994)
The RNA modification database, RNAMDB: 2011 update
William A. Cantara;Pamela F. Crain;Jef Rozenski;James A. McCloskey.
Nucleic Acids Research (2011)
The RNA Modification Database: 1999 update
Jef Rozenski;Pamela F. Crain;James A. McCloskey.
Nucleic Acids Research (1999)
The RNA modification database
Pamela F. Crain;James A. McCloskey.
Nucleic Acids Research (1996)
Use of deuterium-labeled trimethylsilyl derivatives in mass spectrometry
James A. McCloskey;Richard N. Stillwell;A. M. Lawson.
Analytical Chemistry (1968)
Interpretation of oligonucleotide mass spectra for determination of sequence using electrospray ionization and tandem mass spectrometry
Jinsong Ni;Steven C. Pomerantz;Jef Rozenski;and Yizhou Zhang.
Analytical Chemistry (1996)
A novel method for the determination of posttranscriptional modification in RNA by mass spectrometry
Jeffrey A. Kowalak;Steven C. Pomerantz;Pamela F. Crain;James A. McCloskey.
Nucleic Acids Research (1993)
Analysis of RNA hydrolyzates by liquid chromatography-mass spectrometry.
Steven C. Pomerantz;James A. McCloskey.
Methods in Enzymology (1990)
The role of posttranscriptional modification in stabilization of transfer RNA from hyperthermophiles.
Jeffrey A. Kowalak;Joseph J. Dalluge;James A. McCloskey;Karl O. Stetter.
Biochemistry (1994)
Application of Mass Spectrometry to Structure Problems.1 VI. Nucleosides2
K. Biemann;James A. McCloskey.
Journal of the American Chemical Society (1962)
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