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James A. McCloskey

James A. McCloskey

D-Index & Metrics

Chemistry

D-Index
78
Citations
17340
World Ranking
3900
National Ranking
1244

Research.com Recognitions

  • 2009 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

James A. McCloskey was affiliated with the University of Utah in the United States. Their research primarily focused on the field of Medicine, with extensive contributions to subfields including Hematology, Genetics, Public Health, Environmental and Occupational Health, Radiology, Nuclear Medicine and Imaging, and Molecular Biology.

They authored research covering various main topics throughout their career, such as:

  • Chronic Myeloid Leukemia Treatments
  • Chronic Lymphocytic Leukemia Research
  • Acute Lymphoblastic Leukemia research
  • Advanced MRI Techniques and Applications
  • Medical Imaging Techniques and Applications
  • Maritime Navigation and Safety
  • Maritime Transport Emissions and Efficiency

James A. McCloskey contributed to multiple publications across several venues, with the most frequent being:

  • Clinical Lymphoma Myeloma & Leukemia
  • International Journal of Naval Architecture and Ocean Engineering
  • Leukemia
  • Blood Neoplasia

Some of their recent published papers included:

  • "A methodology to define risk matrices - Application to inland water ways autonomous ships" (2022), published in International Journal of Naval Architecture and Ocean Engineering
  • "Patient-reported outcomes in Philadelphia chromosome-positive acute lymphoblastic leukemia patients treated with ponatinib or imatinib: results from the PhALLCON trial" (2025), published in Leukemia
  • "V-FAST: a phase 1b master trial to investigate CPX-351 combined with targeted agents in adults with newly diagnosed AML" (2025), published in Blood Neoplasia
  • "CML-047 Post Hoc Analysis of Responses to Ponatinib in Patients With Chronic-Phase Chronic Myeloid Leukemia (CP-CML) by Baseline BCR::ABL1 Level and Baseline Mutation Status in the OPTIC Trial" (2022), published in Clinical Lymphoma Myeloma & Leukemia
  • "Poster: CML-047 Post Hoc Analysis of Responses to Ponatinib in Patients With Chronic-Phase Chronic Myeloid Leukemia (CP-CML) by Baseline BCR::ABL1 Level and Baseline Mutation Status in the OPTIC Trial" (2022), published in Clinical Lymphoma Myeloma & Leukemia

The scientist collaborated frequently with other researchers, including:

  • Philippe Rousselot
  • Alexander Vorog
  • Ibrahim Aldoss
  • Pau Montesinos
  • Pankit Vachhani

James A. McCloskey received the Fellow of the American Association for the Advancement of Science (AAAS) award in 2009.

Best Publications

  • Summary: the modified nucleosides of RNA

    Patrick A. Limbach;Pamela F. Crain;James A. McCloskey

  • The RNA modification database

    Pamela F. Crain;James A. McCloskey

  • A novel method for the determination of posttranscriptional modification in RNA by mass spectrometry

    Jeffrey A. Kowalak;Steven C. Pomerantz;Pamela F. Crain;James A. McCloskey

  • Use of deuterium-labeled trimethylsilyl derivatives in mass spectrometry

    James A. McCloskey;Richard N. Stillwell;A. M. Lawson

  • Interpretation of oligonucleotide mass spectra for determination of sequence using electrospray ionization and tandem mass spectrometry.

    Jinsong Ni;Steven C. Pomerantz;Jef Rozenski;and Yizhou Zhang

  • Analysis of RNA hydrolyzates by liquid chromatography-mass spectrometry.

    Steven C. Pomerantz;James A. McCloskey

  • The role of posttranscriptional modification in stabilization of transfer RNA from hyperthermophiles.

    Jeffrey A. Kowalak;Joseph J. Dalluge;James A. McCloskey;Karl O. Stetter

  • Structure of the modified nucleoside Q isolated from Escherichia coli transfer ribonucleic acid. 7-(4,5-cis-Dihydroxy-1-cyclopenten-3-ylaminomethyl)-7-deazaguanosine.

    H Kasai;Z Oashi;F Harada;S Nishimura

  • Application of Mass Spectrometry to Structure Problems.1 VI. Nucleosides2

    K. Biemann;James A. McCloskey

  • Posttranscriptional modification of tRNA in thermophilic archaea (Archaebacteria).

    C. G. Edmonds;P. F. Crain;Ramesh Gupta;T. Hashizume

  • Mass Spectra of O-Isopropylidene Derivatives of Unsaturated Fatty Esters

    James A. McCloskey;Martha J. McClelland

  • Modified nucleosides in transfer RNA

    James A. McCloskey;Susumu Nishimura

  • An aminoacyl-tRNA synthetase that specifically activates pyrrolysine

    Carla Polycarpo;Alexandre Ambrogelly;Amélie Bérubé;SusAnn M. Winbush

  • Determination of oligonucleotide composition from mass spectrometrically measured molecular weight

    Steven C. Pomerantz;Jeffrey A. Kowalak;James A. McCloskey

  • Conformational Flexibility in RNA: The Role of Dihydrouridine

    Joseph J. Dalluge;Takeshi Hashizume;Alan E. Sopchik;James A. McCloskey

  • Mass spectrometry of nucleic acid components. Trimethylsilyl derivatives of nucleotides, nucleosides, and bases

    James A. McCloskey;A. M. Lawson;K. Tsuboyama;P. M. Krueger

  • Presence and location of modified nucleotides in Escherichia coli tmRNA: structural mimicry with tRNA acceptor branches

    Brice Felden;Kyoko Hanawa;John F. Atkins;Hyouta Himeno

  • The mechanism of adenosine to inosine conversion by the double-stranded RNA unwinding/modifying activity: a high-performance liquid chromatography-mass spectrometry analysis.

    Andrew G. Polson;Pamela F. Crain;Steven C. Pomerantz;James A. McCloskey

  • Posttranscriptional Modifications in 16S and 23S rRNAs of the Archaeal Hyperthermophile Sulfolobus solfataricus

    Kathleen R. Noon;Eveline Bruenger;James A. McCloskey

  • Chemical ionization mass spectrometry of nucleosides. Mechanisms of ion formation and estimations of proton affinity.

    M. S. Wilson;James A. McCloskey

  • Fast atom bombardment combined with tandem mass spectrometry for the determination of nucleosides

    Frank W. Crow;Kenneth B. Tomer;Michael L. Gross;James A. McCloskey

Frequent Co-Authors

Susumu Nishimura
Susumu Nishimura University of Tsukuba
Karl O. Stetter
Karl O. Stetter University of Regensburg
David L. Smith
David L. Smith University of Washington
Takuya Ueda
Takuya Ueda University of Tokyo
Leroy B. Townsend
Leroy B. Townsend University of Michigan–Ann Arbor
Tatsuo Miyazawa
Tatsuo Miyazawa University of Tokyo
Dieter Söll
Dieter Söll Yale University
Patrick A. Limbach
Patrick A. Limbach University of Cincinnati
Yoshiyuki Kuchino
Yoshiyuki Kuchino National Cancer Research Institute, UK

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