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Chemistry

D-Index
60
Citations
13232
World Ranking
9677
National Ranking
2719

Research.com Recognitions

  • 1995 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Leroy B. Townsend is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily lies within the field of Neuroscience, specifically focusing on areas such as Cellular and Molecular Neuroscience, Genetics, Endocrinology, Diabetes and Metabolism, Molecular Biology, and Cognitive Neuroscience.

The scientific topics addressed in their work include:

  • Neurobiology and Insect Physiology Research
  • Genetic Syndromes and Imprinting
  • Growth Hormone and Insulin-like Growth Factors
  • Epigenetics and DNA Methylation
  • Neural dynamics and brain function
  • Olfactory and Sensory Function Studies
  • Marine and coastal ecosystems

They have contributed to various publications with a focus on neurodevelopmental and ecological subjects. Notable recent papers authored or co-authored by Leroy B. Townsend include:

  • Deficits in higher visual area representations in a mouse model of Angelman syndrome, 2020, Journal of Neurodevelopmental Disorders
  • Mesoscale functional architecture in medial posterior parietal cortex, 2023, bioRxiv (Cold Spring Harbor Laboratory)
  • A touchscreen based global motion perception task for mice, 2020, UNC Libraries
  • Stream-dependent development of higher visual cortical areas, 2020, UNC Libraries
  • Ecological role of a cosmopolitan testate rhizopod, Paulinella ovalis, in the microbial food web of a eutrophic estuary, 2024, Journal of Plankton Research

Townsend has published frequently in the following venues:

  • UNC Libraries
  • Journal of Neurodevelopmental Disorders
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Plankton Research

The researcher has collaborated regularly with several colleagues, including:

  • Spencer L. Smith (4 co-authored works)
  • Jeffrey N. Stirman (2 co-authored works)
  • Nathan S. Hall (2 co-authored works)
  • Kelly A. Jones (1 co-authored work)
  • Christopher R. Dorsett (1 co-authored work)

In recognition of their contributions to science, Leroy B. Townsend was named a Fellow of the American Association for the Advancement of Science (AAAS) in 1995.

Best Publications

  • Potent and Selective Inhibition of Human Cytomegalovirus Replication by 1263W94, a Benzimidazole l-Riboside with a Unique Mode of Action

    Karen K. Biron;Robert J. Harvey;Stanley C. Chamberlain;Steven S. Good

  • Inhibition of Human Cytomegalovirus DNA Maturation by a Benzimidazole Ribonucleoside Is Mediated through the UL89 Gene Product

    Mark R. Underwood;Robert J. Harvey;Sylvia C. Stanat;Mary Lou Hemphill

  • Carbon-13 magnetic resonance. XXVI. A quantitative determination of the tautomeric populations of certain purines.

    Marie T. Chenon;Ronald J. Pugmire;David M. Grant;Raymond P. Panzica

  • Design, synthesis, and antiviral activity of certain 2,5,6-trihalo-1-(beta-D-ribofuranosyl)benzimidazoles.

    Leroy B. Townsend;Rodrigo V. Devivar;Steven R. Turk;Steven R. Turk;M. Reza Nassiri

  • Resistance of Human Cytomegalovirus to Benzimidazole Ribonucleosides Maps to Two Open Reading Frames: UL89 and UL56

    Paula M. Krosky;Mark R. Underwood;Steven R. Turk;Kathryne W.-H. Feng

  • Carbon-13 magnetic resonance. XXV. Basic set of parameters for the investigation of tautomerism in purines established from carbon-13 magnetic resonance studies using certain purines and pyrrolo[2,3-d]pyrimidines

    Marie T. Chenon;Ronald J. Pugmire;David M. Grant;Raymond P. Panzica

  • In vitro activities of benzimidazole D- and L-ribonucleosides against herpesviruses.

    Stephanie L. Williams;Caroll B. Hartline;Nicole L. Kushner;Emma A. Harden

  • Inhibition of purine nucleoside phosphorylase by 8-aminoguanosine: selective toxicity for T lymphoblasts

    Irene S. Kazmers;Beverly S. Mitchell;Peter E. Dadonna;Linda L. Wotring

  • Synthesis and antiviral activity of novel erythrofuranosyl imidazo[1,2-a]pyridine C-nucleosides constructed via palladium coupling of iodoimidazo[1,2-a]pyridines and dihydrofuran.

    Kristjan S. Gudmundsson;John D. Williams;John C. Drach;Leroy B. Townsend

  • Pyrrolopyrimidine nucleosides. 3. The total synthesis of toyocamycin, sangivamycin, tubercidin, and related derivatives.

    Richard L. Tolman;Roland K. Robins;Leroy B. Townsend

  • Synthesis of 2,4-disubstituted thiazoles and selenazoles as potential antitumor and antifilarial agents: 1. Methyl 4-(isothiocyanatomethyl)thiazole-2-carbamates, -selenazole-2- carbamates, and related derivatives.

    Yatendra Kumar;Rachel Green;Katherine Z. Borysko;Dean S. Wise

  • Pyrrolo[2,3-d]pyrimidine nucleosides as inhibitors of human cytomegalovirus.

    S R Turk;C Shipman;R Nassiri;G Genzlinger

  • Synthesis, antiproliferative, and antiviral activity of certain 4-substituted and 4,5-disubstituted 7-[(1,3-dihydroxy-2-propoxy)methyl]pyrrolo[2,3-d]pyrimidines.

    J S Pudlo;M R Nassiri;E R Kern;L L Wotring

  • PURINE NUCLEOSIDES. VI. FURTHER METHYLATION STUDIES OF NATURALLY OCCURRING PURINE NUCLEOSIDES.

    Arthur D. Broom;Leroy B. Townsend;Jesse W. Jones;Roland K. Robins

  • The synthesis and chemistry of certain anthelmintic benzimidazoles

    Leroy B. Townsend;Dean S. Wise

  • Preclinical and toxicology studies of 1263W94, a potent and selective inhibitor of human cytomegalovirus replication.

    George W. Koszalka;Nelson W. Johnson;Steven S. Good;Leslie Boyd

  • PYRAZOLOPYRIMIDINE NUCLEOSIDES. 12. SYNTHESIS AND BIOLOGICAL ACTIVITY OF CERTAIN PYRAZOLO(3,4-D)PYRIMIDINE NUCLEOSIDES RELATED TO ADENOSINE

    G. A. Bhat;J.-L. G. Montero;R. P. Panzica;L. L. Wotring

  • Design, synthesis, and biological evaluation of tricyclic nucleosides (dimensional probes) as analogues of certain antiviral polyhalogenated benzimidazole ribonucleosides.

    Zhijian Zhu;Blaise Lippa;John C. Drach;Leroy B. Townsend

  • Structure of the nucleoside antibiotics formycin, formyein B and laurusin

    Roland K. Robins;Leroy B. Townsend;Frederick Cassidy;John F. Gerster

  • Benzimidazole Ribonucleosides: Design, Synthesis, and Antiviral Activity of Certain 2-(Alkylthio)- and 2-(Benzylthio)-5,6-dichloro-1-(.beta.-D-ribofuranosyl)benzimidazoles

    Rodrigo V. Devivar;Etsuko Kawashima;Ganapathi R. Revankar;Julie M. Breitenbach

  • Mass spectrometry of nucleic acid constituents. Trimethylsilyl derivatives of nucleosides

    Henrianna Pang;Karl H. Schram;David L. Smith;S. P. Gupta

Frequent Co-Authors

Roland K. Robins
Roland K. Robins University of Utah
Eric E. Swayze
Eric E. Swayze Ionis Pharmaceuticals (United States)
Ronald J. Pugmire
Ronald J. Pugmire University of Utah
David M. Grant
David M. Grant University of Nottingham
James A. McCloskey
James A. McCloskey University of Utah
John W. McCall
John W. McCall University of Georgia
Donna S. Shewach
Donna S. Shewach University of Michigan–Ann Arbor
Fung-Lung Chung
Fung-Lung Chung Georgetown University
Jan Balzarini
Jan Balzarini KU Leuven
Robert W. Buckheit
Robert W. Buckheit ImQuest BioSciences (United States)

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