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Chemistry

D-Index
81
Citations
18825
World Ranking
3334
National Ranking
1099

Overview

David C. Muddiman is affiliated with North Carolina State University in the United States. Their research spans multiple scientific disciplines, with a primary focus on chemistry and biochemistry, genetics, and molecular biology. The scientist's work often crosses into specialized subfields such as spectroscopy, molecular biology, ecology, biomedical engineering, and biophysics.

The core areas of Muddiman's investigations include mass spectrometry techniques and applications, metabolomics and mass spectrometry studies, analytical chemistry and chromatography, glycosylation and glycoproteins research, advanced proteomics techniques and applications, isotope analysis in ecology, and spectroscopy techniques in biomedical and chemical research.

Frequent collaborators in their research efforts have included Kenneth P. Garrard, Alexandria L. Sohn, Kevan T. Knizner, Alena N. Joignant, and Russell R. Kibbe.

Muddiman has contributed extensively to the scientific literature, with notable papers such as:

  • The development and application of matrix assisted laser desorption electrospray ionization: The teenage years (2021), Mass Spectrometry Reviews
  • Effects of Prenatal Exposure to a Mixture of Organophosphate Flame Retardants on Placental Gene Expression and Serotonergic Innervation in the Fetal Rat Brain (2020), Toxicological Sciences
  • An adaptive teosinte mexicana introgression modulates phosphatidylcholine levels and is associated with maize flowering time (2022), Proceedings of the National Academy of Sciences
  • Next-Generation Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Source for Mass Spectrometry Imaging and High-Throughput Screening (2022), Journal of the American Society for Mass Spectrometry
  • Methods for Cryosectioning and Mass Spectrometry Imaging of Whole-Body Zebrafish (2020), Journal of the American Society for Mass Spectrometry

The scientist's work has been published predominantly in a set of recurring journals:

  • Journal of the American Society for Mass Spectrometry
  • Journal of Mass Spectrometry
  • Analytical and Bioanalytical Chemistry
  • Rapid Communications in Mass Spectrometry
  • Journal of Proteome Research

David C. Muddiman's research integrates advanced methodologies in mass spectrometry with applications spanning both chemical and biological systems. Their expertise includes development of novel ionization sources and mass spectrometry imaging techniques, as well as applications in metabolomics and proteomics.

Best Publications

  • Generation and Detection of Multiply-Charged Peptides and Proteins by Matrix-Assisted Laser Desorption Electrospray Ionization (MALDESI) Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

    Jason S. Sampson;Adam M. Hawkridge;David C. Muddiman

  • MSiReader: An Open-Source Interface to View and Analyze High Resolving Power MS Imaging Files on Matlab Platform

    Guillaume Robichaud;Kenneth P. Garrard;Jeremy A. Barry;David C. Muddiman

  • Performance Characteristics of a New Hybrid Quadrupole Time-of-Flight Tandem Mass Spectrometer (TripleTOF 5600)

    Genna L. Andrews;Brigitte L. Simons;J. Bryce Young;Adam M. Hawkridge

  • Absolute Quantification of the Model Biomarker Prostate-Specific Antigen in Serum by LC-MS/MS Using Protein Cleavage and Isotope Dilution Mass Spectrometry

    David R. Barnidge;Marcia K. Goodmanson;George G. Klee;David C. Muddiman

  • Quantitative mass spectral evidence for the absence of circulating brain natriuretic peptide (BNP-32) in severe human heart failure

    Adam M. Hawkridge;Denise M. Heublein;H. Robert Bergen;Alessandro Cataliotti

  • Improving wood properties for wood utilization through multi-omics integration in lignin biosynthesis

    Jack P. Wang;Megan L. Matthews;Cranos M. Williams;Rui Shi

  • MSiReader v1.0: Evolving Open-Source Mass Spectrometry Imaging Software for Targeted and Untargeted Analyses

    Mark T. Bokhart;Milad Nazari;Kenneth P. Garrard;Kenneth P. Garrard;David C. Muddiman

  • Coordination-driven self-assemblies with a carborane backbone.

    Hershel Jude;Hendrik Disteldorf;Sonja Fischer;Tim Wedge

  • Characterization of PCR products from bacilli using electrospray ionization FTICR mass spectrometry.

    David C. Muddiman;David S. Wunschel;Chuanliang Liu;Ljiljana Paša-Tolić

  • Transition-Metal-Mediated Rational Design and Self-Assembly of Chiral, Nanoscale Supramolecular Polyhedra with Unique T Symmetry†

    Peter J. Stang;Bogdan Olenyuk;David C. Muddiman;Richard D. Smith

  • Mass Spectrometry–Based Biomarker Discovery: Toward a Global Proteome Index of Individuality

    Adam M. Hawkridge;David C. Muddiman

  • Human Proteinpedia enables sharing of human protein data.

    Suresh Mathivanan;Suresh Mathivanan;Mukhtar Ahmed;Natalie G Ahn;Hainard Alexandre

  • Length and Base Composition of PCR-Amplified Nucleic Acids Using Mass Measurements from Electrospray Ionization Mass Spectrometry

    David C. Muddiman;Gordon A. Anderson;and Steven A. Hofstadler;Richard D. Smith

  • A New Family of Multiferrocene Complexes with Enhanced Control of Structure and Stoichiometry via Coordination-Driven Self-Assembly and Their Electrochemistry

    Hai Bo Yang;Koushik Ghosh;Yue Zhao;Brian H. Northrop

  • Charge-state reduction with improved signal intensity of oligonucleotides in electrospray ionization mass spectrometry

    David C. Muddiman;Xueheng Cheng;Harold R. Udseth;Richard D. Smith

  • Hemoglobinase Activity of the Lysine Gingipain Protease (Kgp) of Porphyromonas gingivalis W83

    Janina P. Lewis;Janet A. Dawson;James C. Hannis;David Muddiman

  • Complete Proteomic-Based Enzyme Reaction and Inhibition Kinetics Reveal How Monolignol Biosynthetic Enzyme Families Affect Metabolic Flux and Lignin in Populus trichocarpa

    Jack P. Wang;Jack P. Wang;Punith P. Naik;Hsi-Chuan Chen;Rui Shi

  • Epithelial ovarian cancer: disease etiology, treatment, detection, and investigational gene, metabolite, and protein biomarkers.

    Taufika Islam Williams;Kristina L. Toups;Diana A. Saggese;Kimberly R. Kalli

  • Membrane protein complexes catalyze both 4- and 3-hydroxylation of cinnamic acid derivatives in monolignol biosynthesis

    Hsi-Chuan Chen;Quanzi Li;Christopher M. Shuford;Jie Liu

  • IR-MALDESI Mass Spectrometry Imaging of Biological Tissue Sections Using Ice as a Matrix

    Guillaume Robichaud;Jeremy A. Barry;David C. Muddiman

  • Molecular Architecture via Coordination: Marriage of Crown Ethers and Calixarenes with Molecular Squares, Unique Tetranuclear Metallamacrocycles from Metallacrown Ether and Metallacalixarene Complexes via Self-Assembly

    Peter J. Stang;Danh H. Cao;Kuanchiang Chen;Gary M. Gray

  • A dual electrospray ionization source combined with hexapole accumulation to achieve high mass accuracy of biopolymers in Fourier transform ion cyclotron resonance mass spectrometry.

    James C. Hannis;David C. Muddiman

Frequent Co-Authors

Vincent L. Chiang
Vincent L. Chiang North Carolina State University
Ronald R. Sederoff
Ronald R. Sederoff North Carolina State University
Peter J. Stang
Peter J. Stang University of Utah
Richard D. Smith
Richard D. Smith Pacific Northwest National Laboratory
Ralph A. Dean
Ralph A. Dean North Carolina State University
Hai-Bo Yang
Hai-Bo Yang East China Normal University
Daniel L. Comins
Daniel L. Comins North Carolina State University
Angela D. M. Kashuba
Angela D. M. Kashuba University of North Carolina at Chapel Hill

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