D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 61 Citations 11,691 138 World Ranking 2325 National Ranking 1150

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • DNA repair

Robert M. Brosh focuses on Helicase, DNA, Werner Syndrome Helicase, Molecular biology and Genetics. His Helicase research is multidisciplinary, incorporating perspectives in Genome instability, DNA repair and DNA replication. His DNA repair research is multidisciplinary, relying on both DNA damage and Proliferating cell nuclear antigen.

The DNA study combines topics in areas such as Gene and Bloom syndrome. The various areas that he examines in his Werner Syndrome Helicase study include Holliday junction, RecQ helicase and Cell biology. Robert M. Brosh has included themes like Promoter, Transcription factor II F, RNA polymerase II, Transcription factor II D and RNA polymerase II holoenzyme in his Molecular biology study.

His most cited work include:

  • The Bloom’s and Werner’s syndrome proteins are DNA structure-specific helicases (478 citations)
  • Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest. (353 citations)
  • FANCJ helicase defective in Fanconia anemia and breast cancer unwinds G-quadruplex DNA to defend genomic stability. (293 citations)

What are the main themes of his work throughout his whole career to date?

Robert M. Brosh mostly deals with Helicase, DNA repair, DNA, Genetics and Genome instability. His work carried out in the field of Helicase brings together such families of science as Molecular biology, DNA replication and Cell biology. His Molecular biology study combines topics in areas such as Cockayne syndrome, Werner Syndrome Helicase and Recombinant DNA.

Robert M. Brosh interconnects Mutation, DNA damage and Homologous recombination in the investigation of issues within DNA repair. His DNA research includes elements of RNA Helicase A, Replication protein A and Computational biology. His Genome instability research includes themes of Flap structure-specific endonuclease 1 and Bloom syndrome.

He most often published in these fields:

  • Helicase (71.60%)
  • DNA repair (54.32%)
  • DNA (50.00%)

What were the highlights of his more recent work (between 2015-2021)?

  • DNA (50.00%)
  • Helicase (71.60%)
  • Cell biology (24.69%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in DNA, Helicase, Cell biology, DNA repair and DNA replication. His studies deal with areas such as Computational biology, Transcription, Nucleic acid and Genome as well as DNA. Robert M. Brosh connects Helicase with Chromosome instability in his study.

His Cell biology research is multidisciplinary, incorporating elements of Homologous recombination, Cancer cell, Genome instability, Molecular biology and G-quadruplex. His DNA repair study incorporates themes from Nucleic acid metabolism, DNA damage and Werner syndrome. His work deals with themes such as Werner Syndrome Helicase and DNA synthesis, which intersect with DNA replication.

Between 2015 and 2021, his most popular works were:

  • G-quadruplexes and helicases. (213 citations)
  • A Long Noncoding RNA Regulates Sister Chromatid Cohesion (56 citations)
  • Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA. (38 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

Robert M. Brosh mainly focuses on DNA replication, DNA repair, DNA, Helicase and Cell biology. His DNA replication study is associated with Genetics. His study in the field of Werner Syndrome Helicase, G-quadruplex and RNA Helicase A also crosses realms of Guanine.

His biological study spans a wide range of topics, including HMG-box and DNA damage, Genome instability. The study incorporates disciplines such as Epigenetics, Gene and Fanconi anemia in addition to DNA damage. His work carried out in the field of DNA brings together such families of science as Replication protein A, Nucleic acid and Molecular biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The Bloom’s and Werner’s syndrome proteins are DNA structure-specific helicases

Payam Mohaghegh;Julia K. Karow;Robert M. Brosh;Vilhelm A. Bohr.
Nucleic Acids Research (2001)

734 Citations

Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest.

Angelos Constantinou;Madalena Tarsounas;Julia K Karow;Robert M Brosh.
EMBO Reports (2000)

448 Citations

Functional and physical interaction between WRN helicase and human replication protein A.

Robert M. Brosh;David K. Orren;Jan O. Nehlin;Peter H. Ravn.
Journal of Biological Chemistry (1999)

405 Citations

Ku complex interacts with and stimulates the Werner protein

Marcus P. Cooper;Amrita Machwe;David K. Orren;Robert M. Brosh.
Genes & Development (2000)

405 Citations

Detection of G-quadruplex DNA in mammalian cells

Alexander Henderson;Yuliang Wu;Yu Chuan Huang;Elizabeth A. Chavez.
Nucleic Acids Research (2014)

374 Citations

FANCJ helicase defective in Fanconia anemia and breast cancer unwinds G-quadruplex DNA to defend genomic stability.

Yuliang Wu;Kazuo Shin-ya;Robert M. Brosh.
Molecular and Cellular Biology (2008)

362 Citations

Replication Protein A Physically Interacts with the Bloom's Syndrome Protein and Stimulates Its Helicase Activity

Robert M. Brosh;Ji-Liang Li;Mark K. Kenny;Julia K. Karow;Julia K. Karow.
Journal of Biological Chemistry (2000)

320 Citations

DNA helicases involved in DNA repair and their roles in cancer

Robert M. Brosh.
Nature Reviews Cancer (2013)

306 Citations

Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity.

Robert M. Brosh;Cayetano von Kobbe;Joshua A. Sommers;Parimal Karmakar.
The EMBO Journal (2001)

299 Citations

G-quadruplexes and helicases.

Oscar Mendoza;Anne Bourdoncle;Anne Bourdoncle;Jean-Baptiste Boulé;Jean-Baptiste Boulé;Robert M. Brosh.
Nucleic Acids Research (2016)

268 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Robert M. Brosh

Vilhelm A. Bohr

Vilhelm A. Bohr

National Institutes of Health

Publications: 159

Ian D. Hickson

Ian D. Hickson

University of Copenhagen

Publications: 59

Deborah L. Croteau

Deborah L. Croteau

National Institutes of Health

Publications: 38

Patrick Sung

Patrick Sung

The University of Texas Health Science Center at San Antonio

Publications: 31

David M. Wilson

David M. Wilson

Hasselt University

Publications: 28

John A. Tainer

John A. Tainer

The University of Texas MD Anderson Cancer Center

Publications: 25

Junko Oshima

Junko Oshima

University of Washington

Publications: 25

Alessandro Vindigni

Alessandro Vindigni

Washington University in St. Louis

Publications: 25

Shankar Balasubramanian

Shankar Balasubramanian

University of Cambridge

Publications: 23

Raymond J. Monnat

Raymond J. Monnat

University of Washington

Publications: 23

Jean-Louis Mergny

Jean-Louis Mergny

École Polytechnique

Publications: 22

Peter M. Lansdorp

Peter M. Lansdorp

University of British Columbia

Publications: 21

Yasuhiro Furuichi

Yasuhiro Furuichi

National Institute of Genetics

Publications: 21

Binghui Shen

Binghui Shen

City Of Hope National Medical Center

Publications: 20

Nancy Maizels

Nancy Maizels

University of Washington

Publications: 18

Stephen Neidle

Stephen Neidle

University College London

Publications: 17

Trending Scientists

Bran Selic

Bran Selic

Malina Software Corp.

Aaron J. Danner

Aaron J. Danner

National University of Singapore

Denise M. G. Freire

Denise M. G. Freire

Federal University of Rio de Janeiro

Raquel Osorio

Raquel Osorio

University of Granada

Yang Shen

Yang Shen

National Institute of Diabetes and Digestive and Kidney Diseases

Xing-Long Wu

Xing-Long Wu

Northeast Normal University

Hamilton O. Smith

Hamilton O. Smith

J. Craig Venter Institute

Jason T. Weir

Jason T. Weir

University of Toronto

Kevin L. O'Hara

Kevin L. O'Hara

University of California, Berkeley

Gary E. Lyons

Gary E. Lyons

University of Wisconsin–Madison

Carmen Buchrieser

Carmen Buchrieser

Institut Pasteur

Eric D. Galbraith

Eric D. Galbraith

McGill University

Charles M. Henderson

Charles M. Henderson

University of Calgary

David A. Shapiro

David A. Shapiro

University of Sheffield

Richard C. Mohs

Richard C. Mohs

Eli Lilly (United States)

Mark Beeson

Mark Beeson

University of Western Australia

Something went wrong. Please try again later.